# NCCN Guidelines® vs IOTOX Algorithm

The clearest difference is rating: IOTOX Algorithm at 5.0 against NCCN Guidelines®'s 3.6. NCCN Guidelines®'s advantage is ratings volume (24 vs 1) and device support (3 vs 1). On price, update cadence, ads and in-app purchases there is nothing between them.

Both are free to download. Neither carries in-app purchases, so what you see is what you pay.

IOTOX Algorithm holds the better App Store score, 5.0 against 3.6. That said, the two scores are not equally well evidenced: NCCN Guidelines® has 24 ratings behind it against 1, so its average is the more settled of the two.

NCCN Guidelines® ships an update every 2 months, IOTOX Algorithm every 6 weeks. The most recent releases landed on October 4, 2026 and September 30, 2026 respectively.

## The numbers

| Metric | NCCN Guidelines® | IOTOX Algorithm |
| --- | --- | --- |
| Price | Free | Free |
| Rating | [3.6 (24 ratings)](https://appshunter.io/ios/app/nccn-guidelines/id775500217/reviews) | **[5.0 (1 ratings)](https://appshunter.io/ios/app/iotox-algorithm/id6744123485/reviews)** |
| Number of ratings | **24** | 1 |
| Positive reviews | 12.5% of reviews | — |
| In-app purchases | No | No |
| Ads | No | No |
| Update frequency | Every 2 months | **Every 6 weeks** |
| Monetization | Free | Free |
| Size | 118 MB | 7 MB |
| Requires iOS | **13.1** | 18.0 |
| Devices | **iPhone, iPad, iPod** | iPhone |
| Age rating | 17+ | 17+ |
| Developer | [National Comprehensive Cancer Network®](https://appshunter.io/developer/1168594705) | [MD Anderson Cancer Center](https://appshunter.io/developer/618340093) |

## What reviewers say

### NCCN Guidelines®

[App page](https://appshunter.io/ios/app/nccn-guidelines/id775500217)

This app provides healthcare professionals with convenient access to comprehensive clinical practice guidelines for oncology. It aims to improve the quality and effectiveness of cancer care by offering evidence-based recommendations for diagnosis, treatment, and supportive services.

**Highlights:** Virtual Library of NCCN Guidelines, Oncology clinical practice guidelines, Evidence-based recommendations, Supports cancer care decision-making, Covers 97% of US cancer cases

**Features:** Vision Pro support

**In-app purchases:** none


### IOTOX Algorithm

[App page](https://appshunter.io/ios/app/iotox-algorithm/id6744123485)

This app provides clinical management algorithms for evaluating, diagnosing, and treating toxicities associated with cancer immunotherapies. It guides physicians on best practices for managing side effects that can arise during cancer treatment.

**Highlights:** Clinical management algorithms, Evaluation of toxicities, Diagnosis of side effects, Treatment of immunotherapy toxicities, Best practices for patient care

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases:** none


## Frequently asked questions

### Is NCCN Guidelines® free?

NCCN Guidelines® is free to download, with no in-app purchases.

### Is IOTOX Algorithm free?

IOTOX Algorithm is free to download, with no in-app purchases.

### Which has better reviews, NCCN Guidelines® or IOTOX Algorithm?

IOTOX Algorithm is rated higher. NCCN Guidelines® averages 3.6 out of 5 from 24 ratings, while IOTOX Algorithm averages 5.0 from 1 ratings.

### Do NCCN Guidelines® or IOTOX Algorithm have ads?

Neither NCCN Guidelines® nor IOTOX Algorithm shows ads.

### Which is updated more often, NCCN Guidelines® or IOTOX Algorithm?

NCCN Guidelines® ships an update every 2 months, and IOTOX Algorithm every 6 weeks. Most recently, NCCN Guidelines® was updated on October 4, 2026 and IOTOX Algorithm on September 30, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*