# Sanford Guide Antimicrobial vs Respiratory Notes

The clearest difference is rating: Sanford Guide Antimicrobial at 4.8 against Respiratory Notes's 4.0. Sanford Guide Antimicrobial also leads on ads (none vs shown) and update cadence (every 2 weeks vs every 6 months). Respiratory Notes's advantage is monetization model (free with in-app purchases vs subscription) and iOS requirement (13.0 vs 15.0). On price, in-app purchases and device support there is nothing between them.

Both are free to download. Sanford Guide Antimicrobial sells 3 in-app purchases, starting at $4.99 per year and Respiratory Notes sells 1 in-app purchase, starting at $39.99 per year. Whichever you choose, the download price is not the number that matters.

Sanford Guide Antimicrobial holds the better App Store score, 4.8 against 4.0. That said, the two scores are not equally well evidenced: Sanford Guide Antimicrobial has 1.9K ratings behind it against 4, so its average is the more settled of the two.

Sanford Guide Antimicrobial ships an update every 2 weeks, Respiratory Notes every 6 months. The most recent releases landed on November 6, 2026 and October 30, 2026 respectively.

## The numbers

| Metric | Sanford Guide Antimicrobial | Respiratory Notes |
| --- | --- | --- |
| Price | Free | Free |
| Rating | **[4.8 (1.9K ratings)](https://appshunter.io/ios/app/sanford-guide-antimicrobial/id863196620/reviews)** | [4.0 (4 ratings)](https://appshunter.io/ios/app/respiratory-notes/id6569241898/reviews) |
| Number of ratings | **1.9K** | 4 |
| Positive reviews | 88.4% of reviews | — |
| In-app purchases | Yes | Yes |
| Ads | **No** | Yes |
| Update frequency | **Every 2 weeks** | Every 6 months |
| Monetization | Subscription | **Free with in-app purchases** |
| Best chart rank | **#5** | — |
| Size | 46 MB | 47 MB |
| Requires iOS | 15.0 | **13.0** |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Age rating | 17+ | 17+ |
| Developer | [Antimicrobial Therapy, Inc.](https://appshunter.io/developer/443442554) | [Skyscape Medpresso Inc](https://appshunter.io/developer/818609416) |

## What reviewers say

### Sanford Guide Antimicrobial

[App page](https://appshunter.io/ios/app/sanford-guide-antimicrobial/id863196620)

**Currently charting:** #5 Top Grossing · Medical (US App Store)

Provides clinicians with concise, evidence-based answers for infectious disease treatment decisions. Features interactive tools like spectra charts and calculators, updated frequently by an expert editorial team.

**Highlights:** Clinically actionable answers, Institutionally diverse editorial team, Constant updates, Interactive antibacterial spectra chart, Drug-drug interaction checker, Trustworthy calculators for dosing

**Features:** Vision Pro support

**In-app purchases (3)**

| Purchase | Price | Billing |
| --- | --- | --- |
| U.S. Vaccine Guidelines | $4.99 | per year |
| Sanford Guide | $39.99 | per year |
| Sanford Guide All Access | $79.99 | per year |

**What reviewers like**

- 👍 Easy to use
- 🚀 Quick access to information
- 💡 Helpful charts and tables
- 🔍 Comprehensive coverage of infections and treatments
- 📚 Up-to-date content and frequent updates

**What reviewers complain about**

- 🐛 Occasional crashes or freezing
- ⏱️ Slow search function
- 💰 Expensive subscription model
- 🔒 Login issues and subscription verification problems

**Reported bugs**

- App freezing or closing unexpectedly
- Login and subscription verification problems
- Corrupted passwords and inability to reset

**Requested features**

- Side-by-side antibiotic susceptibility comparison
- Offline access to content
- Improved navigation and UI


### Respiratory Notes

[App page](https://appshunter.io/ios/app/respiratory-notes/id6569241898)

This app provides a comprehensive, procedure-based reference for respiratory therapy information. It includes illustrations, forms, and algorithms to aid in study and practice, with content organized around protocols and new pulmonary disease tabs. An in-app purchase unlocks all content, and a subscription offers continuous updates.

**Highlights:** Procedure-based format, Supporting illustrations and tables, Fill-in-the-blank forms, Algorithms based on AARC Guidelines, SmartSearch technology, Offline content access

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases (1)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Respiratory Notes | $39.99 | per year |


## Frequently asked questions

### Is Sanford Guide Antimicrobial free?

Sanford Guide Antimicrobial is free to download, with in-app purchases available.

### Is Respiratory Notes free?

Respiratory Notes is free to download, with in-app purchases available.

### Which has better reviews, Sanford Guide Antimicrobial or Respiratory Notes?

Sanford Guide Antimicrobial is rated higher. Sanford Guide Antimicrobial averages 4.8 out of 5 from 1.9K ratings, while Respiratory Notes averages 4.0 from 4 ratings.

### Do Sanford Guide Antimicrobial or Respiratory Notes have ads?

Respiratory Notes shows ads; Sanford Guide Antimicrobial does not.

### Which is updated more often, Sanford Guide Antimicrobial or Respiratory Notes?

Sanford Guide Antimicrobial ships an update every 2 weeks, and Respiratory Notes every 6 months. Most recently, Sanford Guide Antimicrobial was updated on November 6, 2026 and Respiratory Notes on October 30, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*