# Mosby's Drug Reference vs Drug Interaction Checker +

The clearest difference is monetization model: Mosby's Drug Reference at free with in-app purchases against Drug Interaction Checker +'s subscription. Mosby's Drug Reference also leads on rating (4.6 vs 4.1) and ratings volume (235 vs 67). Drug Interaction Checker +'s advantage is update cadence (every 4 days vs every 9 months) and review sentiment (50% vs 32%). On price, ads, in-app purchases and device support there is nothing between them.

Both are free to download. Mosby's Drug Reference sells 1 in-app purchase, starting at $45.99 per year and Drug Interaction Checker + sells 3 in-app purchases, starting at $4.99 per month. Whichever you choose, the download price is not the number that matters.

Mosby's Drug Reference holds the better App Store score, 4.6 against 4.1. Both are backed by a comparable volume of ratings — 235 and 67 respectively. Written reviews complicate that: 32% of Mosby's Drug Reference's written reviews are positive against 50% of Drug Interaction Checker +'s, so the app with the better star average is not the one people write more warmly about.

Mosby's Drug Reference ships an update every 9 months, Drug Interaction Checker + every 4 days. Both last shipped on October 24, 2026.

## The numbers

| Metric | Mosby's Drug Reference | Drug Interaction Checker + |
| --- | --- | --- |
| Price | Free | Free |
| Rating | **[4.6 (235 ratings)](https://appshunter.io/ios/app/mosbys-drug-reference/id959042883/reviews)** | [4.1 (67 ratings)](https://appshunter.io/ios/app/drug-interaction-checker-plus/id1313254656/reviews) |
| Number of ratings | **235** | 67 |
| Positive reviews | 31.8% of reviews | **50.0% of reviews** |
| In-app purchases | Yes | Yes |
| Ads | No | No |
| Update frequency | Every 9 months | **Every 4 days** |
| Monetization | **Free with in-app purchases** | Subscription |
| Size | 9 MB | 10 MB |
| Requires iOS | 15.0 | **11.0** |
| Devices | **iPhone, iPad, iPod, Mac** | iPhone, iPad, iPod |
| Age rating | 17+ | 17+ |
| Developer | [Unbound Medicine, Inc.](https://appshunter.io/developer/300420400) | [HYDL](https://appshunter.io/developer/1459757393) |

## What reviewers say

### Mosby's Drug Reference

[App page](https://appshunter.io/ios/app/mosbys-drug-reference/id959042883)

This app provides healthcare professionals with comprehensive drug information, including actions, usage, dosage, interactions, and side effects. It emphasizes patient safety with Black Box Warnings, Safety Alerts, and information on life-threatening side effects. Features include custom notes, highlights, and quick search functionality.

**Highlights:** Over 5,000 drug listings, Black Box Warnings and Safety Alerts, Drug action, usage, dosage, interactions, side effects, Custom notes and highlights, Full text search, Appendix of recent FDA-approvals

**Features:** Vision Pro support

**In-app purchases (1)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Mosby's Drug Reference | $45.99 | per year |

**What reviewers like**

- 👍 Great reference for nursing students
- 👍 Reliable resource for medication information
- 👍 Invaluable for looking up drugs quickly
- 👍 Helpful for answering patient questions
- 👍 Easy and best to use mobile drug reference

**What reviewers complain about**

- 😞 Routinely does not have drugs
- 😞 Not for Canadian market
- 😞 Not categorized and searchable
- 😞 Cannot customize info display
- 😞 Most patients' meds weren't there

**Reported bugs**

- Every time I search norco or hydrocodone hydrochlorothiazide comes up

**Requested features**

- Version for people in the dental field
- Create an app version for dental drug reference
- Separate favorites list for users and spouses


### Drug Interaction Checker +

[App page](https://appshunter.io/ios/app/drug-interaction-checker-plus/id1313254656)

This app provides a comprehensive guide to medications, allowing users to check drug interactions, identify pills, and find drug alternatives. It offers detailed information on dosages, pharmacology, and adverse events for patients and healthcare professionals.

**Highlights:** Drug interaction checker, Pill identifier, Drug alternatives, Dosage and pharmacology information, Adverse event details, Search approved drugs by indication

**Features:** macOS Compatibility, Vision Pro support

**In-app purchases (3)**

| Purchase | Price | Billing |
| --- | --- | --- |
| Drug Interaction Checker | $4.99 | per month |
| All Access: Drug Reference | $9.99 | per month |
| Basic: Annual | $49.99 | per year |


## Frequently asked questions

### Is Mosby's Drug Reference free?

Mosby's Drug Reference is free to download, with in-app purchases available.

### Is Drug Interaction Checker + free?

Drug Interaction Checker + is free to download, with in-app purchases available.

### Which has better reviews, Mosby's Drug Reference or Drug Interaction Checker +?

Mosby's Drug Reference is rated higher. Mosby's Drug Reference averages 4.6 out of 5 from 235 ratings, while Drug Interaction Checker + averages 4.1 from 67 ratings.

### Do Mosby's Drug Reference or Drug Interaction Checker + have ads?

Neither Mosby's Drug Reference nor Drug Interaction Checker + shows ads.

### Which is updated more often, Mosby's Drug Reference or Drug Interaction Checker +?

Mosby's Drug Reference ships an update every 9 months, and Drug Interaction Checker + every 4 days. Most recently, Mosby's Drug Reference was updated on October 24, 2026 and Drug Interaction Checker + on October 24, 2026.

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*Compared by [AppsHunter](https://appshunter.io/) from daily US App Store data. Review summaries are generated from verbatim App Store reviews.*