Palio 2024

Meeting summary and key questions: The rapid advancement of artificial intelligence (AI), machine learning (ML), and new digital technologies has catalyzed groundbreaking transformations across diverse industries, and the realm of vaccine development is no exception. This Palio 2024 edition will delve into the multifaceted roles of AI, ML, and new technologies in shaping the landscape of vaccine research and development, exploring innovative approaches, and addressing pertinent challenges. We will explore how AI/ML can contribute to: • Understanding diseases, epidemiology, and pathogenesis • Optimizing antigen identification, design, and product development • Improving the efficiency of clinical trials, safety assessment, and pharmacovigilance • Improving vaccine production processes and supply • Maximizing vaccine distributive justice in LMIC • Achieving health-related sustainable development goals • Improving vaccine communication and countering vaccine hesitancy