Use this Almost Every Day
This app is very useful for the clinical pharmacist responsible for kinetic dosing. It is quick, simple to use and works well. Have found this provides more accurate predictions for geriatric patients, in comparison to other kinetics calculators tried in the past.
Love it
I like this app it's simple and to the points. Pretty handy when your on the floor. You don't have too many options to confuse you but you can still adjust VD to your liking. I'm surprised this app is not reviewed or used that much.
Very helpful
This has been the most useful app for doing pharmacokinetics that I found. It does the calculations for aminoglycosides, vancomycin and high dose extended interval dosing. I have been using it for over five years. It's efficient, no frills interface is quick and can save a lot of time. Highly recommended!
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OK but needs work
There is no report feature. At least condense the results and relevant data on a single screen that can be air-printed or sent to the device camera roll. As others noted, there are slim pickings for iPhone kinetics apps. This app is a worthy effort but it needs some improvement.
RxCalc
I have been a clinical pharmacist for 19-years. For the last 8-10 years, I have been using ClinRx on my palm. Unfortunately, ClinRx is not available for I-Pod/I-Phone. I misplaced my palm and was looking for an alternate program. I had seen a review from a professor at UC San Francisco praising RxCalc. I purchased this program based on that review. I found it less than useless. I plugged in the data for a large, relatively young patient with a high vancomycin trough. The data for the single level vancomycin trough provided data that was completely inaccurate. I tried again with similar data. Again, the resultant data was exactly opposite of what someone who is familiar with pharmacokinetics would expect. Example: 1500mg every 8 hours with a reported trough of 28 at 1/2 hour prior to next dose in a 128kg patient recommends a NEW dose of 1750mg every 8 hours for a goal trough of 18. If the trough is already higher than desired, why would you want to increase the dose? The original data on an actual patient provided a Tau of approximately 3 hours when the actual Tau should have been 12-18 hours.
I would not recommend this program, especially if the person purchasing the program does not have enough experience to recognize when the data being provided is not accurate.
I would not recommend this program, especially if the person purchasing the program does not have enough experience to recognize when the data being provided is not accurate.
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Response from developer
Hello. We finally have the ability to reply to our reviews and I'd love to hear any feedback you would like to provide. Do you happen to know the model ClinRx is using? RxCalc is based on the Creighton model. There are many to choose from and we'd love to know the model you prefer. Please send any feedback you'd like to provide to support@applecorelabs.com. Thanks for taking the time to write a review.
its ok
I found that when using 2 levels to calculate phamacokinetics that the VD is way off from any equations I have seen. Also it does not extrapolate a Cmin and Cmax. This program is useful for calculating first doses. I hope this can be fixed in the next update since this is the only kinetic program I could find for the apple.
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Response from developer
Hello. RxCalc is based on the Creighton model. There are many to choose from and we'd love to know the model you prefer. Please send any feedback you'd like to provide to support@applecorelabs.com. We love hearing from users of RxCalc. Thanks for taking the time to write a review.
RxCalc is Quite Useful
As already mentioned, there may be some underdosing initially. Perhaps, one tends to expect too much when the equations predict a serum level of 13.7 mcg/ml and then the actual measured level turns out to be ONLY 12.1 mcg/ml and, therefore, is incorrect!. Mathematical equations, by their nature, are very exact. Yet they are applied in the same manner to the many differences among our patients. When I use any pharmacokinetic dosing model in an empirical fashion I am simply looking to be in the correct ball park once I have an actual level with which to work. RxCalc helps me do this without spending a lot of time and effort coming up with a regimen that will most likely be changed after the first serum level is measured and reported. Not having many options is no reason not to use RxCalc. This is an iPhone app after all, not software to run on the hospital's mainframe! However, I am disappointed that when adjusting dosing based on measured levels I must have both a peak and a trough. Most of the time I only have a trough and am unable to use RxCalc to assist in adjusting the dosing. I have been assured by Apple Core Labs that making the entry of a peak level optional is currently being tested and should be expected in the next RxCalc release.
Robert Martin, PharmD
Robert Martin, PharmD
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Needs transparency
Like others I found this program to significantly underdose patients. The Ke value calculated to about half that of accepted methods. The equation for Ke should be made transparent. The program should also offer multiple methods of kinetic dosing.
Severely underdoses!!
This program really underdoses all my patients. It predicts troughs of 20 and 25 with normal doses. I used it just the other day and it predicted a trough of 26.4 and I got an actual trough of 14.7--no changes clinically with the patient. This program is crap. Good thing it only cost 99 cents!
Garbage
Does not work. Interface is clunky and gives me error messages when I put in values. I don't believe for a minute the positive reviews are real. Cannot use product nor would you want to trust calculations (if you can get them from the app!) in a clinical setting. If it smells like garbage, works like garbage, and looks like garbage, it probably is.
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Handy kinetics app
I've been using this app for a week or so, comparing results to a program I've used on my Palm for several years. The two calculate very similar results, and I find myself using RxCalc more and more. There are a couple of tweaks that would be helpful (entering height in centimeters rather than inches, adjustable volume of distribution), but so far this has been a great app.
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No like
The interface is rigid and clunky. Wouldn't let me get a ballpark on levels without filling in every single box, including height (140-age/SCr...I can get clearance that quickly in my head for the avg pt since 70kg is avg wt...just give me the option of putting in the CrCl myself and save me several minutes fighting with your funky screens...and while you're at it, take some constructive feedback to make a better product instead of posting bogus 5 star reviews). Rather put pen to paper. Never tried the ag calcs but to be honest will probably delete and never use. Bye bye 6 bucks.
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Great kinetics app!
I have been using this for a couple of weeks for both new starts and follow ups and think it is great. I was using a desk top program and it is so much more conveinent to have this on my phone. I'm not sure what the previous reviewer was complaining about. Of course you have to enter all the patient information in order to get any dosing information. You can't even figure something as basic as creatinine clearance without the patient's height and weight! Also, all kinetics programs that I have used give you sort of an odd dose and frequency. The program gives you the exact dose and frequency needed to get you exactly the levels you asked for and then you have to use your clinical judgement and plug in some numbers into the program to find a more reasonable dose. In any case, I am finding this to be a great app!
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Handy, kinetics right at my fingertips!
I've been using this ap on a daily basis since the first release. It's a simple to use, concise ap that lets me blow through my new starts and make adjustments on the fly. Very convenient not to have to log in to our PC based kinetics application, which is cumbersome and clunky. (do it by hand, you say? Forget about it! I haven't it done one by "hand" since I HAD to, in school). A few minor things I'd like to see with the next upgrade, but mostly to do with personal preference. Definately a solid little ap that's easy and convenient to use. Great little timesaver.
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Kinetics Slayer!
This is the kinetics calculator I have been waiting for! Well done to say the least. And at $5.99 it is a pure bargain! I put it through the paces and have been very pleased with its capabilities thus far. Screens are easy to navigate and there is plenty of dosing/serum level manipulation. A great start for some much needed pharmacy apps. Strong work Apple Core. Thanks!
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