Captisol AR vs Medplace

Captisol is a beta-cyclodextrin with an average of 7 sulfobutylether (SBE) substitutions per molecule that was rationally designed to improve the solubility, stability, bioavailability and dosing of biologically active compounds. Ollomol AR for Captisol was designed to visualize in 3D-AR a number of Captisol-based supramolecular complexes. It allows viewing in an immersive way the movement of the structures at atomic resolution, explicitly considering all the classical degrees of freedom. The movies were generated by Molecular Dynamics simulations using the GROMACS software and the GROMOS force field with a specific parameterization for Captisol (considering a structure with four SBE groups positioned on the C6-OH of alternating glucose rings and three additional SBE groups placed on the C3-OH of the remaining glucose rings of the cyclodextrin).

Medplace takes the hassle out of obtaining and sharing top medical expertise. From peer reviews to case reviews and beyond, Medplace is the platform that seamlessly curates and connects the best practicing doctors and nurses to organizations that need them. Join the Movement to Make Healthcare Better Better healthcare hinges on better access to expertise. That’s why we created Medplace – to unlock the expertise of the best clinicians in the country and extend your impact across the industry. Medplace attracts thousands of top medical specialists and healthcare professional applicants, but we only accept a small percentage that meets our rigorous criteria.