Ankyras vs VentSim

Ankyras makes the intracranial aneurysm treatment planning easier, accessible and more interactive. Intended use: Ankyras is a medical software intended to assist healthcare professionals in the selection of a proper braided stent device for the treatment of intracranial aneurysms. • Login for full access: Registered users can log in to access their case list and saved simulations. (Note: Medical images cannot be viewed on the mobile app.) • Access without login: Unregistered users can still open shared simulations without logging in. Shared cases can be accessed directly via a “View Case” email link. • Open shared simulations – You will receive an email when another user share a simulation with you. In the mail, click View case: Ankyras app will directly open the case. • Vessel morphology – Explore and quantify the vessel morphology to assess the fit of the desired braided device in the patients’ anatomy. • See, move and change FD devices – easily simulate the different devices and adjust their position if needed along the vessel. • Share simulations – Click the left corner menu button and share the simulation with others to facilitate case discussion. Ankyras includes both a free-registration version and a user-registration version with complete case processing features. You can get registered in www.ankyrasonline.com from a laptop or PC to get access to all simulation processing functionalities. The Ankyras support team will be in contact with you and facilitate the indications and instructions to start preparing your own simulations. Ankyras is a Medical Device manufactured by Mentice Spain S.L. and distributed by Mentice subsidiaries and partners in approved markets. Mentice Spain S.L. (SRN: ES-MF-000036826) is ISO 13485 certified with number MD 784027. Ankyras is CE marked under MDR (MDR 784032) and holds UKCA certification (UKCA 784033). It is 510(k) cleared by the FDA (K230006) and notified to ANVISA (registration number 81118630030). Ankyras v6.0-CE UDI-DI: 8437025622023. NB 2797 All operators must read the complete Instructions for Use before operating the ANKYRAS. The product should be used only by qualified and trained personnel. ANKYRAS is intended for exclusive use by professional users. The software is intended to assist healthcare professionals in the planning of endovascular treatment with flow diverters and cannot fully substitute their clinical judgement. The software should only be used in combination with equipment with the minimum system requirements listed. If the minimum system requirements are not met the system may not work as expected. For more information, please refer to the eIFU, available here: https://www.mentice.com/ankyras/ifu

VentSim is a fully functioning, high fidelity, physiologically faithful mechanical ventilator simulator. It was developed by Dr. Roger Stedman for iOS using the Swift programming language. Its purpose is an educational tool for critical care doctors, nurses, therapists, and anaesthetists – essentially anyone that has an interest in the provision of safe, effective care of the mechanically ventilated patient. VentSim uses a mathematical model of the human respiratory system (volumes, resistance and compliance) which are well established models published in the literature [link]. These have been codified with an interface developed which allows you to manipulate parameters to simulate different patient scenarios (everything from a neonate through to an adult with severe COPD and emphysema). VentSim allows you to apply ventilator settings to your respiratory system model and then generates pressure, volume and flow signals that are displayed on your iOS device. Using VentSim On launch VentSim takes you straight into the simulator view – this is your central navigation point for the app. Set up your simulated patient Tap the ‘Patient’ button on the right side of the navigator bar. This brings up the ‘Patient Settings’ view: The controls will slide in from the right, allowing you to still see some of the simulator view as you make adjustments. Select your type of patient - and then adjust weight and relative lung volume size. You will see calculated lung volumes. Select linear or dynamic compliance If linear is selected adjust the ‘Compliance Slider’ (mls/cmH2O). Alternatively - explore the dynamic compliance model and try different compliance models. Adjust the Time constant, this will adjust airway resistance according to the size and compliance of your patient. Return to the simulator view by tapping the right arrow in the navigator bar. Adjust your ventilator settings Select the ‘Ventilator’ button to the left of the navigator bar. This brings up the ‘Ventilator Settings’ view: Select your ventilator rate (bpm) and I:E ratio using the sliders. You have a choice of three ventilator modes; Pressure Control, Volume Control and Flow Control. You are able to adjust appropriate input values for each of these (Inspiratory pressure, tidal volume or inspiratory flow) as well as apply PEEP and in volume control mode add an end inspiratory pause. Return to the simulator view to view the impact your settings have had on your patients respiratory parameters. Optimise the simulator view If you are finding that due to screen size information is hidden (as is the case with the iPhone SE) try turning your device on its side into landscape mode. The simulator view in landscape mode on an iPhone SE Each simulator graph view has a gear icon in the top right hand corner, tap this to bring up the view settings panel. This allows you to change the background color, plot color, speed of animation, animation type (default is the wrap fade mode) and plot style (line or solid). Graph Plot View settings popover You will notice that as you change your settings the graph plots will automatically re-scale to an optimum screen fit. The axis labels will adjust accordingly. The panel data is updated at the end of each respiratory cycle. Other Features The ‘i’ (information) button on the navigator bar opens a mini-browser which navigates automatically to this page. The down pointing chevron button on the navigator opens a menu with which to access other features of the simulator which allows you to switch on and off each individual view and also add in the spirometer loop view and also the compliance view. Have fun! Please feedback to: ventsim@rogerstedman.com ventsim@rogerstedman.com