PneumoRecs VaxAdvisor vs BoneCalc

This is the PneumoRecs VaxAdvisor App created by the Centers for Disease Control and Prevention (CDC) in collaboration with the Georgia Tech Research Institute. PneumoRecs VaxAdvisor provides patient-specific pneumococcal vaccination guidance consistent with the pneumococcal vaccination recommendations of the Advisory Committee on Immunization Practices. Vaccination providers enter a patient’s age and respond to prompts about the patient’s pneumococcal vaccination history and underlying medical conditions. The app then displays patient-specific pneumococcal vaccination recommendations consistent with the recommended U.S. immunization schedule.

The BoneCalc app is designed for the calculation of Z-scores and percentiles for bone mineral content (BMC) and areal bone mineral density (aBMD) for children under 20 years of age, as measured by dual-energy X-ray absorptiometry (DXA), for the following sites: whole-body subtotal (total-body-less-head), total hip, femoral neck, lumbar spine, distal ⅓ radius and ultradistal radius. Separate race-specific (Black and non-Black) and race-neutral calculations are available by age and sex. Height-Z–adjusted Z-scores for these measures are also calculated. The BMC and aBMD data are derived from the CHOP Bone Mineral Density in Childhood Study: race-specific for ages 5–20 [Zemel B et al., J Clin Endocrinol Metab 2011;96(10):3160–3169]; race-specific for ages 1–5 [Kalkwarf HJ et al., J Clin Endocrinol Metab 2022;107(9):e3887–e3900]; and race-neutral ages 5–20 [Zemel BS et al., J Clin Endocrinol Metab 2025;110(11):3034–3048]. Calculations are also available for lumbar-spine bone mineral apparent density (BMAD) for children 5–20 years of age: race-specific [Kindler JM et al. J Clin Endocrinol Metab 2019;104(4):1283–1292] and race-neutral [Zemel BS et al., J Clin Endocrinol Metab 2025;110(11):3034–3048].