Comparison

iTIVA Anesthesia Plus vs Regional Anesthesia Reference

Price, ratings, monetisation and update history for both apps, side by side — with what reviewers say about each.

Head to head
About

iTIVA Anesthesia Plus

This app simulates drug concentrations in plasma and optimizes infusion schemes for medical professionals. It offers a comprehensive drug library, target-controlled infusion simulation, and MAC age calculation. Users can explore drug interactions, share cases, and export data.

Highlights
  • Accurate drug concentration estimation
  • Target Controlled Infusion (TCI) simulation
  • Comprehensive drug library (28 drugs)
  • Explore drug interactions (70 PK, 10 PD models)
  • MAC Age Calculation
  • Intraoperative milestones & case sharing
  • Save and run multiple simulations
  • Excel data export
Features
Read full description

Introducing iTIVA: Your Ultimate Pharmacokinetic / Pharmacodynamic Simulation App Are you a medical professional looking to enhance precision and efficiency in drug administration while expanding your knowledge in pharmacokinetics? Look no further than iTIVA, the leading pharmacokinetic/pharmacodynamic simulation application designed to revolutionize the way you estimate drug concentrations in plasma and optimize infusion schemes! Key Features: • Accurate Drug Concentration Estimation: Harness the power of cutting-edge mathematical models to estimate drug concentrations in plasma. iTIVA offers an extensive library of 28 drugs and 70 pharmacokinetic models, empowering you to control anesthesia IV drugs like an expert. • Target Controlled Infusion (TCI) Simulation: Take control of TCI pumps like never before! iTIVA simulates TCI pump behavior, allowing you to calculate infusion schemes to attain and maintain desired target concentrations in plasma or effect site. It's like having a reliable assistant right at your fingertips. • Comprehensive Drug Library: From Remifentanil, Propofol to Heparin and beyond, iTIVA boasts an impressive range of 28 drugs to cater to your unique needs. (Remifentanil, Fentanyl, Sufentanil, Alfentanil, Hydromorphone, Morphine, Ketamine, Procaine, Lidocaine, Propofol, Etomidate, Dexmedetomidine, Midazolam, Remimazolam, Thiopental, Atracurium, Cisatracurium, Rocuronium, Vecuronium, Sugammadex, Tranexamic, Magnesium sulfate, Diazepam, Heparin and Protamine) • Explore Drug Interactions: With 70 pharmacokinetic models and 10 pharmacodynamic models at your disposal, iTIVA facilitates in-depth exploration of drug interactions. • MAC Age Calculation: Quickly determine end-tidal (Et) concentration for Isoflurane, Sevoflurane, and Desflurane using the Mapleson equation. No more guesswork – iTIVA streamlines the process for you. • Intraoperative Milestones & Case Sharing: Record crucial intraoperative milestones and effortlessly share cases with colleagues using QR codes. Collaboration has never been this seamless! • Save and Run Multiple Simulations: Save your simulation cases for future review or run multiple simulations simultaneously. iTIVA adapts to your workflow and maximizes efficiency. • Excel Data Export: All recorded information can be conveniently exported as an Excel file. Stay organized and analyze your data with ease. iTIVA's yearly subscription is available for US$9,99/year.  • The subscription will be charged to iTunes Account at confirmation of purchase • Subscription automatically renews unless auto-renew is turned off at least 24-hours before the end of the current period • The account will be charged for renewal within 24-hours before the end of the current period, and identify the cost of the renewal • Subscriptions may be managed by the user and auto-renewal may be turned off by going to the user's Account Settings after purchase • Any unused portion of a free trial period, if offered, will be forfeited when the user purchases a subscription to that publication, where applicable More details can be found here iTIVA Privacy Policy: https://itiva.co/privacy.html Terms and Conditions: http://itiva.co/terms.html

About

Regional Anesthesia Reference

This app offers a quick reference for regional nerve block placement using ultrasound. It includes detailed anatomy, patient positioning, and technique videos, along with a local anesthetic drug calculator.

Highlights
  • Ultrasound guidance for nerve blocks
  • Anatomy and positioning guides
  • Block placement technique videos
  • Local anesthetic drug calculator
  • List of current blocks
Features
Read full description

Regional Anesthesia Reference provides a quick look at the anatomy, positioning, and techniques for placing regional nerve blocks under ultrasound guidance. This includes ultrasound images and anatomic descriptions, images of patient positioning, and videos of block placement. Current blocks include: Interscalene Supraclavicular Infraclavicular Axillary Femoral Adductor Canal Suprainguinal Fascia Iliaca TAP Rectus Sheath Sciatic (Popliteal) A local anesthetic drug calculator is also included for assistance with calculating maximum dosages and percent of max dose delivered for a given patient. This is a weight based calculator using dosages from Miller's Anesthesia or Morgan and Mikhail.

Screenshots

iTIVA Anesthesia Plus4 screens
Regional Anesthesia Reference4 screens

Verdict

The call

The clearest difference is in-app purchases: Regional Anesthesia Reference at none against iTIVA Anesthesia Plus's 2. Regional Anesthesia Reference also leads on review sentiment (89% vs 73%) and rating (5.0 vs 4.8). iTIVA Anesthesia Plus's advantage is update cadence (every 2 months vs every 5 months) and ratings volume (330 vs 32). On price, ads and device support there is nothing between them.

Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS

CostPrice · In-app purchases · Ads · Monetization

Both are free to download. iTIVA Anesthesia Plus sells 2 in-app purchases, starting at $9.99 per year. Regional Anesthesia Reference asks for nothing beyond the download.

ReceptionRating · Positive reviews · Number of ratings

Regional Anesthesia Reference holds the better App Store score, 5.0 against 4.8. That said, the two scores are not equally well evidenced: iTIVA Anesthesia Plus has 330 ratings behind it against 32, so its average is the more settled of the two. Written reviews point the same way: 73% of iTIVA Anesthesia Plus's written reviews are positive against 89% of Regional Anesthesia Reference's.

UpkeepUpdate frequency

iTIVA Anesthesia Plus ships an update every 2 months, Regional Anesthesia Reference every 5 months. The most recent releases landed on October 16, 2026 and September 25, 2026 respectively.

Scorecard7 real differences · 3 level
iTIVA Anesthesia Plus versus Regional Anesthesia Reference: the parameters behind the verdict, then further details
ParameteriTIVA Anesthesia PlusRegional Anesthesia Reference
PriceFreeFree
Rating4.8 (330 ratings)5.0 (32 ratings) — better
Positive reviews72.7% of reviews88.9% of reviews — better
Number of ratings330 — better32
Update frequencyEvery 2 months — betterEvery 5 months
AdsNoNo
In-app purchasesYesNo — better
MonetizationSubscriptionFree — better
DevicesiPhone, iPad, iPodiPhone, iPad, iPod
Requires iOS11.08.0 — better
Further details — not scored
Size125 MB89 MB
Age rating17+17+
DeveloperANESTESIARTE CALI SASUniversity Of Washington

Customer experience

iTIVA Anesthesia Plus

All ratings330 ratings
Positive94.8%
Neutral1.8%
Negative3.3%
Written reviews11 reviews
Positive72.7%
Neutral18.2%
Negative9.1%

Regional Anesthesia Reference

All ratings32 ratings
Positive100.0%
Neutral0.0%
Negative0.0%
Written reviews9 reviews
Positive88.9%
Neutral11.1%
Negative0.0%

In-app purchases

2 purchases

iTIVA Anesthesia Plus

Subscriptions2
  • iTIVA yearly$9.991 Year
  • iTIVA yearly 2021$9.991 Year
None

Regional Anesthesia Reference

No in-app purchases

Questions

Is iTIVA Anesthesia Plus free?
iTIVA Anesthesia Plus is free to download, with in-app purchases available.
Is Regional Anesthesia Reference free?
Regional Anesthesia Reference is free to download, with no in-app purchases.
Which has better reviews, iTIVA Anesthesia Plus or Regional Anesthesia Reference?
Regional Anesthesia Reference is rated higher. iTIVA Anesthesia Plus averages 4.8 out of 5 from 330 ratings, while Regional Anesthesia Reference averages 5.0 from 32 ratings.
Do iTIVA Anesthesia Plus or Regional Anesthesia Reference have ads?
Neither iTIVA Anesthesia Plus nor Regional Anesthesia Reference shows ads.
Which is updated more often, iTIVA Anesthesia Plus or Regional Anesthesia Reference?
iTIVA Anesthesia Plus ships an update every 2 months, and Regional Anesthesia Reference every 5 months. Most recently, iTIVA Anesthesia Plus was updated on October 16, 2026 and Regional Anesthesia Reference on September 25, 2026.

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