Comparison

iTIVA Anesthesia Plus vs Nerbio iTOF

Price, ratings, monetisation and update history for both apps, side by side — with what reviewers say about each.

Head to head
About

iTIVA Anesthesia Plus

This app simulates drug concentrations in plasma and optimizes infusion schemes for medical professionals. It offers a comprehensive drug library, target-controlled infusion simulation, and MAC age calculation. Users can explore drug interactions, share cases, and export data.

Highlights
  • Accurate drug concentration estimation
  • Target Controlled Infusion (TCI) simulation
  • Comprehensive drug library (28 drugs)
  • Explore drug interactions (70 PK, 10 PD models)
  • MAC Age Calculation
  • Intraoperative milestones & case sharing
  • Save and run multiple simulations
  • Excel data export
Features
Read full description

Introducing iTIVA: Your Ultimate Pharmacokinetic / Pharmacodynamic Simulation App Are you a medical professional looking to enhance precision and efficiency in drug administration while expanding your knowledge in pharmacokinetics? Look no further than iTIVA, the leading pharmacokinetic/pharmacodynamic simulation application designed to revolutionize the way you estimate drug concentrations in plasma and optimize infusion schemes! Key Features: • Accurate Drug Concentration Estimation: Harness the power of cutting-edge mathematical models to estimate drug concentrations in plasma. iTIVA offers an extensive library of 28 drugs and 70 pharmacokinetic models, empowering you to control anesthesia IV drugs like an expert. • Target Controlled Infusion (TCI) Simulation: Take control of TCI pumps like never before! iTIVA simulates TCI pump behavior, allowing you to calculate infusion schemes to attain and maintain desired target concentrations in plasma or effect site. It's like having a reliable assistant right at your fingertips. • Comprehensive Drug Library: From Remifentanil, Propofol to Heparin and beyond, iTIVA boasts an impressive range of 28 drugs to cater to your unique needs. (Remifentanil, Fentanyl, Sufentanil, Alfentanil, Hydromorphone, Morphine, Ketamine, Procaine, Lidocaine, Propofol, Etomidate, Dexmedetomidine, Midazolam, Remimazolam, Thiopental, Atracurium, Cisatracurium, Rocuronium, Vecuronium, Sugammadex, Tranexamic, Magnesium sulfate, Diazepam, Heparin and Protamine) • Explore Drug Interactions: With 70 pharmacokinetic models and 10 pharmacodynamic models at your disposal, iTIVA facilitates in-depth exploration of drug interactions. • MAC Age Calculation: Quickly determine end-tidal (Et) concentration for Isoflurane, Sevoflurane, and Desflurane using the Mapleson equation. No more guesswork – iTIVA streamlines the process for you. • Intraoperative Milestones & Case Sharing: Record crucial intraoperative milestones and effortlessly share cases with colleagues using QR codes. Collaboration has never been this seamless! • Save and Run Multiple Simulations: Save your simulation cases for future review or run multiple simulations simultaneously. iTIVA adapts to your workflow and maximizes efficiency. • Excel Data Export: All recorded information can be conveniently exported as an Excel file. Stay organized and analyze your data with ease. iTIVA's yearly subscription is available for US$9,99/year.  • The subscription will be charged to iTunes Account at confirmation of purchase • Subscription automatically renews unless auto-renew is turned off at least 24-hours before the end of the current period • The account will be charged for renewal within 24-hours before the end of the current period, and identify the cost of the renewal • Subscriptions may be managed by the user and auto-renewal may be turned off by going to the user's Account Settings after purchase • Any unused portion of a free trial period, if offered, will be forfeited when the user purchases a subscription to that publication, where applicable More details can be found here iTIVA Privacy Policy: https://itiva.co/privacy.html Terms and Conditions: http://itiva.co/terms.html

About

Nerbio iTOF

This medical application works with a specific device to provide quantitative monitoring of neuromuscular blocking agents. It enhances patient safety and accuracy in monitoring, offering wireless control for caregivers. The system is recommended by anesthesiologists for precise neuromuscular transmission monitoring.

Highlights
  • Quantitative neuromuscular transmission monitoring
  • Works with iTOF device hardware
  • Remote patient monitoring
  • Wireless control for caregivers
  • Automated quantitative monitoring
  • FDA cleared
Read full description

Nerbio’s iTOF® app works with the iTOF device; an FDA cleared, quantitative neuromuscular transmission (NMT) monitor for remote monitoring of neuromuscular blocking agents (NMBAs). The iTOF app is designed to make patient monitoring safer, easier to use, and more accurate than ever. The iTOF is the first mobile device-managed, quantitative monitor of NMBAs. The combination of the app and Bluetooth-connected stimulator device allows precise, automated quantitative monitoring of the level of neuromuscular block. Wireless control also improves caregiver safety while maintaining a high-level of patient care. The iTOF system is recommended by leading anesthesiologists and used around the world for accurate NMBA monitoring. ------------------------------- NOTE: This app requires the iTOF device hardware to perform monitoring. Contact nerbio.com for information. iTOF is a registered trademark of Nerbio Medical Software Platforms, Inc. San Jose, California USA. ------------------------------- NOTE: Nerbio’s iTOF is authorized for use in the following countries: USA CHILE COLOMBIA INDIA -------------------------------

Screenshots

iTIVA Anesthesia Plus4 screens
Nerbio iTOF3 screens

Verdict

The call

The clearest difference is in-app purchases: Nerbio iTOF at none against iTIVA Anesthesia Plus's 2. Nerbio iTOF also leads on rating (5.0 vs 4.8). iTIVA Anesthesia Plus's advantage is ratings volume (330 vs 3) and iOS requirement (11.0 vs 15.6). On price, update cadence, ads and device support there is nothing between them.

Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS

CostPrice · In-app purchases · Ads · Monetization

Both are free to download. iTIVA Anesthesia Plus sells 2 in-app purchases, starting at $9.99 per year. Nerbio iTOF asks for nothing beyond the download.

ReceptionRating · Positive reviews · Number of ratings

Nerbio iTOF holds the better App Store score, 5.0 against 4.8. That said, the two scores are not equally well evidenced: iTIVA Anesthesia Plus has 330 ratings behind it against 3, so its average is the more settled of the two.

UpkeepUpdate frequency

Both ship on a similar rhythm, roughly every 2 months. The most recent releases landed on September 23, 2026 and September 10, 2026 respectively.

Scorecard5 real differences · 5 level
iTIVA Anesthesia Plus versus Nerbio iTOF: the parameters behind the verdict, then further details
ParameteriTIVA Anesthesia PlusNerbio iTOF
PriceFreeFree
Rating4.8 (330 ratings)5.0 (3 ratings) — better
Positive reviews72.7% of reviews—
Number of ratings330 — better3
Update frequencyEvery 2 monthsEvery 2 months
AdsNoNo
In-app purchasesYesNo — better
MonetizationSubscriptionFree — better
DevicesiPhone, iPad, iPodiPhone, iPad, iPod
Requires iOS11.0 — better15.6
Further details — not scored
Size125 MB87 MB
Age rating17+17+
DeveloperANESTESIARTE CALI SASNerbio Medical Software Platform Inc

Customer experience

iTIVA Anesthesia Plus

All ratings330 ratings
Positive94.8%
Neutral1.8%
Negative3.3%
Written reviews11 reviews
Positive72.7%
Neutral18.2%
Negative9.1%

Nerbio iTOF

All ratings3 ratings
Positive100.0%
Neutral0.0%
Negative0.0%

In-app purchases

2 purchases

iTIVA Anesthesia Plus

Subscriptions2
  • iTIVA yearly$9.991 Year
  • iTIVA yearly 2021$9.991 Year
None

Nerbio iTOF

No in-app purchases

Questions

Is iTIVA Anesthesia Plus free?
iTIVA Anesthesia Plus is free to download, with in-app purchases available.
Is Nerbio iTOF free?
Nerbio iTOF is free to download, with no in-app purchases.
Which has better reviews, iTIVA Anesthesia Plus or Nerbio iTOF?
Nerbio iTOF is rated higher. iTIVA Anesthesia Plus averages 4.8 out of 5 from 330 ratings, while Nerbio iTOF averages 5.0 from 3 ratings.
Do iTIVA Anesthesia Plus or Nerbio iTOF have ads?
Neither iTIVA Anesthesia Plus nor Nerbio iTOF shows ads.
Which is updated more often, iTIVA Anesthesia Plus or Nerbio iTOF?
iTIVA Anesthesia Plus ships an update every 2 months, and Nerbio iTOF every 2 months. Most recently, iTIVA Anesthesia Plus was updated on September 23, 2026 and Nerbio iTOF on September 10, 2026.

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