iTIVA Anesthesia Plus vs Guide Dose
Price, ratings, monetisation and update history for both apps, side by side — with what reviewers say about each.
iTIVA Anesthesia Plus
This app simulates drug concentrations in plasma and optimizes infusion schemes for medical professionals. It offers a comprehensive drug library, target-controlled infusion simulation, and MAC age calculation. Users can explore drug interactions, share cases, and export data.
- Accurate drug concentration estimation
- Target Controlled Infusion (TCI) simulation
- Comprehensive drug library (28 drugs)
- Explore drug interactions (70 PK, 10 PD models)
- MAC Age Calculation
- Intraoperative milestones & case sharing
- Save and run multiple simulations
- Excel data export
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Introducing iTIVA: Your Ultimate Pharmacokinetic / Pharmacodynamic Simulation App Are you a medical professional looking to enhance precision and efficiency in drug administration while expanding your knowledge in pharmacokinetics? Look no further than iTIVA, the leading pharmacokinetic/pharmacodynamic simulation application designed to revolutionize the way you estimate drug concentrations in plasma and optimize infusion schemes! Key Features: • Accurate Drug Concentration Estimation: Harness the power of cutting-edge mathematical models to estimate drug concentrations in plasma. iTIVA offers an extensive library of 28 drugs and 70 pharmacokinetic models, empowering you to control anesthesia IV drugs like an expert. • Target Controlled Infusion (TCI) Simulation: Take control of TCI pumps like never before! iTIVA simulates TCI pump behavior, allowing you to calculate infusion schemes to attain and maintain desired target concentrations in plasma or effect site. It's like having a reliable assistant right at your fingertips. • Comprehensive Drug Library: From Remifentanil, Propofol to Heparin and beyond, iTIVA boasts an impressive range of 28 drugs to cater to your unique needs. (Remifentanil, Fentanyl, Sufentanil, Alfentanil, Hydromorphone, Morphine, Ketamine, Procaine, Lidocaine, Propofol, Etomidate, Dexmedetomidine, Midazolam, Remimazolam, Thiopental, Atracurium, Cisatracurium, Rocuronium, Vecuronium, Sugammadex, Tranexamic, Magnesium sulfate, Diazepam, Heparin and Protamine) • Explore Drug Interactions: With 70 pharmacokinetic models and 10 pharmacodynamic models at your disposal, iTIVA facilitates in-depth exploration of drug interactions. • MAC Age Calculation: Quickly determine end-tidal (Et) concentration for Isoflurane, Sevoflurane, and Desflurane using the Mapleson equation. No more guesswork – iTIVA streamlines the process for you. • Intraoperative Milestones & Case Sharing: Record crucial intraoperative milestones and effortlessly share cases with colleagues using QR codes. Collaboration has never been this seamless! • Save and Run Multiple Simulations: Save your simulation cases for future review or run multiple simulations simultaneously. iTIVA adapts to your workflow and maximizes efficiency. • Excel Data Export: All recorded information can be conveniently exported as an Excel file. Stay organized and analyze your data with ease. iTIVA's yearly subscription is available for US$9,99/year. • The subscription will be charged to iTunes Account at confirmation of purchase • Subscription automatically renews unless auto-renew is turned off at least 24-hours before the end of the current period • The account will be charged for renewal within 24-hours before the end of the current period, and identify the cost of the renewal • Subscriptions may be managed by the user and auto-renewal may be turned off by going to the user's Account Settings after purchase • Any unused portion of a free trial period, if offered, will be forfeited when the user purchases a subscription to that publication, where applicable More details can be found here iTIVA Privacy Policy: https://itiva.co/privacy.html Terms and Conditions: http://itiva.co/terms.html
Guide Dose
This app provides healthcare professionals and students with quick access to clinical information, drug doses, and decision-support tools. It features a structured experience for study, reference, and organizing medical data, including AI-powered informational support.
- Search by medication or indication
- Patient profile for contextualized readings
- Organized clinical references and labeling
- Modules on physiology, medications, and CPR
- Clinical AI for informational support
- Protocols and consultation flows
- Auxiliary clinical tools
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Guide Dose brings together clinical information, educational references, and clinical decision-support tools in a fast, clear, organized experience for iPhone and iPad. Developed by MedCalc LTDA, a Brazilian medical research and technology company, Guide Dose was created to support study, reference consultation, and the organization of clinical information. The app uses structured content, responsible language, and fluid navigation to help healthcare professionals and advanced students access medical information more clearly. Guide Dose does not replace clinical judgment, individualized prescribing, institutional protocols, official labeling, or government sources. Its purpose is to provide informational and educational support for review, consultation, and clinical workflow organization. FEATURES • Search by medication or indication. • Patient profile with age, weight, height, sex, and age range to contextualize readings and auxiliary tools. • Clinical references and official labeling organized in one environment. • Modules on physiology, medications, intubation pathways, and CPR support. • Clinical AI for informational support, with answers in an educational format. • Protocols and consultation flows for reviewing relevant topics. • Auxiliary tools grouped in a dedicated section, intended for reference use only. • Multilingual support for consultation in different languages. • Dark interface, readable typography, and fluid navigation within the Apple ecosystem. WHO IT IS FOR Physicians, nurses, pharmacists, and advanced students seeking a tool for study, reference consultation, and organization of clinical information. THE DIFFERENCE Guide Dose organizes clinical information, medical references, and support tools into a structured experience. The focus is clarity, review, medical education, and organization of health information. ABOUT MEDCALC LTDA MedCalc LTDA is a Brazilian company dedicated to research and innovation in medical technology. We develop digital tools that connect scientific evidence, medical education, and clinical information organization. CLINICAL CONTENT Guide Dose content is organized using medical literature, guidelines, official labeling, and recognized protocols. Critical information should always be confirmed with official sources, local guidelines, and institutional protocols. SUBSCRIPTIONS Guide Dose offers auto-renewable plans for full access: • Monthly Plan • Annual Plan Payment is charged to your Apple ID account at confirmation of purchase. The subscription renews automatically unless canceled at least 24 hours before the end of the current period. Manage or cancel in Settings > Apple ID > Subscriptions. PRIVACY Your data is treated seriously. Use fictitious data in demonstrations. In clinical settings, follow your institution’s protocols, applicable law, and best practices for data protection. Privacy Policy: https://guidedose.com.br/privacidade Terms of Use (EULA): https://www.apple.com/legal/internet-services/itunes/dev/stdeula/ UPDATES We continuously improve content, languages, performance, and stability. Download Guide Dose and get an organized tool for study, reference consultation, and clinical workflow support on iPhone and iPad. LEGAL NOTICE Guide Dose is a clinical support, study, and reference tool developed by MedCalc LTDA. It does not replace medical evaluation, prescribing, professional judgment, institutional protocols, official labeling, or official sources. Confirm doses, allergies, interactions, and clinical actions with your team, current guidelines, and primary sources. AI content is informational and educational and may contain inaccuracies. Use implies acceptance of the Terms of Use and Privacy Policy.
Screenshots
Verdict
The clearest difference is update cadence: Guide Dose at every 5 days against iTIVA Anesthesia Plus's every 2 months. Guide Dose also leads on review sentiment (86% vs 73%). iTIVA Anesthesia Plus's advantage is iOS requirement (11.0 vs 15.5). On price, ads, in-app purchases and monetization model there is nothing between them.
Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS
Both are free to download. iTIVA Anesthesia Plus sells 2 in-app purchases, starting at $9.99 per year and Guide Dose sells 2 in-app purchases, starting at $9.99 per month. Whichever you choose, the download price is not the number that matters.
iTIVA Anesthesia Plus ships an update every 2 months, Guide Dose every 5 days. The most recent releases landed on October 16, 2026 and October 3, 2026 respectively.
| Parameter | iTIVA Anesthesia Plus | Guide Dose |
|---|---|---|
| Price | Free | Free |
| Rating | 4.8 (330 ratings) — better | — |
| Positive reviews | 72.7% of reviews | 85.7% of reviews — better |
| Number of ratings | 330 — better | — |
| Update frequency | Every 2 months | Every 5 days — better |
| Ads | No | No |
| In-app purchases | Yes | Yes |
| Monetization | Subscription | Subscription |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Requires iOS | 11.0 — better | 15.5 |
| Further details — not scored | ||
| Size | 125 MB | 144 MB |
| Age rating | 17+ | 12+ |
| Developer | ANESTESIARTE CALI SAS | MedCalc |
Customer experience
iTIVA Anesthesia Plus
Guide Dose
In-app purchases
iTIVA Anesthesia Plus
- iTIVA yearly$9.991 Year
- iTIVA yearly 2021$9.991 Year
Guide Dose
- Guide Dose Pro (monthly)7 Days trial$9.991 Month
- Guide Dose Pro (annual)7 Days trial$69.991 Year
Questions
Is iTIVA Anesthesia Plus free?
Is Guide Dose free?
Do iTIVA Anesthesia Plus or Guide Dose have ads?
Which is updated more often, iTIVA Anesthesia Plus or Guide Dose?
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