Comparison

iTIVA Anesthesia Plus vs Safe Vent

Price, ratings, monetisation and update history for both apps, side by side — with what reviewers say about each.

Head to head
About

iTIVA Anesthesia Plus

This app simulates drug concentrations in plasma and optimizes infusion schemes for medical professionals. It offers a comprehensive drug library, target-controlled infusion simulation, and MAC age calculation. Users can explore drug interactions, share cases, and export data.

Highlights
  • Accurate drug concentration estimation
  • Target Controlled Infusion (TCI) simulation
  • Comprehensive drug library (28 drugs)
  • Explore drug interactions (70 PK, 10 PD models)
  • MAC Age Calculation
  • Intraoperative milestones & case sharing
  • Save and run multiple simulations
  • Excel data export
Features
Read full description

Introducing iTIVA: Your Ultimate Pharmacokinetic / Pharmacodynamic Simulation App Are you a medical professional looking to enhance precision and efficiency in drug administration while expanding your knowledge in pharmacokinetics? Look no further than iTIVA, the leading pharmacokinetic/pharmacodynamic simulation application designed to revolutionize the way you estimate drug concentrations in plasma and optimize infusion schemes! Key Features: • Accurate Drug Concentration Estimation: Harness the power of cutting-edge mathematical models to estimate drug concentrations in plasma. iTIVA offers an extensive library of 28 drugs and 70 pharmacokinetic models, empowering you to control anesthesia IV drugs like an expert. • Target Controlled Infusion (TCI) Simulation: Take control of TCI pumps like never before! iTIVA simulates TCI pump behavior, allowing you to calculate infusion schemes to attain and maintain desired target concentrations in plasma or effect site. It's like having a reliable assistant right at your fingertips. • Comprehensive Drug Library: From Remifentanil, Propofol to Heparin and beyond, iTIVA boasts an impressive range of 28 drugs to cater to your unique needs. (Remifentanil, Fentanyl, Sufentanil, Alfentanil, Hydromorphone, Morphine, Ketamine, Procaine, Lidocaine, Propofol, Etomidate, Dexmedetomidine, Midazolam, Remimazolam, Thiopental, Atracurium, Cisatracurium, Rocuronium, Vecuronium, Sugammadex, Tranexamic, Magnesium sulfate, Diazepam, Heparin and Protamine) • Explore Drug Interactions: With 70 pharmacokinetic models and 10 pharmacodynamic models at your disposal, iTIVA facilitates in-depth exploration of drug interactions. • MAC Age Calculation: Quickly determine end-tidal (Et) concentration for Isoflurane, Sevoflurane, and Desflurane using the Mapleson equation. No more guesswork – iTIVA streamlines the process for you. • Intraoperative Milestones & Case Sharing: Record crucial intraoperative milestones and effortlessly share cases with colleagues using QR codes. Collaboration has never been this seamless! • Save and Run Multiple Simulations: Save your simulation cases for future review or run multiple simulations simultaneously. iTIVA adapts to your workflow and maximizes efficiency. • Excel Data Export: All recorded information can be conveniently exported as an Excel file. Stay organized and analyze your data with ease. iTIVA's yearly subscription is available for US$9,99/year.  • The subscription will be charged to iTunes Account at confirmation of purchase • Subscription automatically renews unless auto-renew is turned off at least 24-hours before the end of the current period • The account will be charged for renewal within 24-hours before the end of the current period, and identify the cost of the renewal • Subscriptions may be managed by the user and auto-renewal may be turned off by going to the user's Account Settings after purchase • Any unused portion of a free trial period, if offered, will be forfeited when the user purchases a subscription to that publication, where applicable More details can be found here iTIVA Privacy Policy: https://itiva.co/privacy.html Terms and Conditions: http://itiva.co/terms.html

About

Safe Vent

Read full description

Safe Vent performs calculations and provides recommendations designed to guide and complement healthcare team decisions in anesthesia/operating rooms, emergencies, and intensive care units. Oxygenation formulas, ventilation, mechanical power, driving pressure, and optimal PEEP predicted by Artificial Intelligence are some of its interesting features. This application does not replace individualized medical judgment for each patient and specific situation. Privacy policy: https://docs.google.com/document/d/1ESNGzHMyY034zsNM9J1f7BLyS47zP1PTvdaTCp1sdfg/edit?pli=1#heading=h.2gfsp4psfhxd Terms and Conditions: https://www.apple.com/legal/internet-services/itunes/dev/stdeula/

Screenshots

iTIVA Anesthesia Plus4 screens
Safe Vent2 screens

Verdict

The call

The clearest difference is iOS requirement: iTIVA Anesthesia Plus at 11.0 against Safe Vent's 13.0. On price, update cadence, ads and in-app purchases there is nothing between them.

Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS

CostPrice · In-app purchases · Ads · Monetization

Both are free to download. iTIVA Anesthesia Plus sells 2 in-app purchases, starting at $9.99 per year and Safe Vent sells 2 in-app purchases, starting at $2.99 per month. Whichever you choose, the download price is not the number that matters.

UpkeepUpdate frequency

iTIVA Anesthesia Plus ships an update every 2 months, Safe Vent every 3 months. The most recent releases landed on September 23, 2026 and September 11, 2026 respectively.

Scorecard1 real difference · 9 level
iTIVA Anesthesia Plus versus Safe Vent: the parameters behind the verdict, then further details
ParameteriTIVA Anesthesia PlusSafe Vent
PriceFreeFree
Rating4.8 (330 ratings) — better—
Positive reviews72.7% of reviews—
Number of ratings330 — better—
Update frequencyEvery 2 months — betterEvery 3 months
AdsNoNo
In-app purchasesYesYes
MonetizationSubscription—
DevicesiPhone, iPad, iPodiPhone, iPad, iPod
Requires iOS11.0 — better13.0
Further details — not scored
Size125 MB58 MB
Age rating17+17+
DeveloperANESTESIARTE CALI SASSYNAPS AI SAS

In-app purchases

2 purchases

iTIVA Anesthesia Plus

Subscriptions2
  • iTIVA yearly$9.991 Year
  • iTIVA yearly 2021$9.991 Year
2 purchases

Safe Vent

Subscriptions2
  • Safe Vent Full Access3 Days trial$2.991 Month
  • Safe Vent Full Access3 Days trial$29.991 Year

Questions

Is iTIVA Anesthesia Plus free?
iTIVA Anesthesia Plus is free to download, with in-app purchases available.
Is Safe Vent free?
Safe Vent is free to download, with in-app purchases available.
Do iTIVA Anesthesia Plus or Safe Vent have ads?
Neither iTIVA Anesthesia Plus nor Safe Vent shows ads.
Which is updated more often, iTIVA Anesthesia Plus or Safe Vent?
iTIVA Anesthesia Plus ships an update every 2 months, and Safe Vent every 3 months. Most recently, iTIVA Anesthesia Plus was updated on September 23, 2026 and Safe Vent on September 11, 2026.

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