BoneCalc vs OpenEvidence

The BoneCalc app is designed for the calculation of Z-scores and percentiles for bone mineral content (BMC) and areal bone mineral density (aBMD) for children under 20 years of age, as measured by dual-energy X-ray absorptiometry (DXA), for the following sites: whole-body subtotal (total-body-less-head), total hip, femoral neck, lumbar spine, distal ⅓ radius and ultradistal radius. Separate race-specific (Black and non-Black) and race-neutral calculations are available by age and sex. Height-Z–adjusted Z-scores for these measures are also calculated. The BMC and aBMD data are derived from the CHOP Bone Mineral Density in Childhood Study: race-specific for ages 5–20 [Zemel B et al., J Clin Endocrinol Metab 2011;96(10):3160–3169]; race-specific for ages 1–5 [Kalkwarf HJ et al., J Clin Endocrinol Metab 2022;107(9):e3887–e3900]; and race-neutral ages 5–20 [Zemel BS et al., J Clin Endocrinol Metab 2025;110(11):3034–3048]. Calculations are also available for lumbar-spine bone mineral apparent density (BMAD) for children 5–20 years of age: race-specific [Kindler JM et al. J Clin Endocrinol Metab 2019;104(4):1283–1292] and race-neutral [Zemel BS et al., J Clin Endocrinol Metab 2025;110(11):3034–3048].

Clinical Decision Support & Medical Search Engine for Healthcare Professionals (NPI Required) OpenEvidence is the most widely used clinical decision support platform and medical search engine among U.S. clinicians. According to independent studies, more American physicians use OpenEvidence than all other AI platforms combined. OpenEvidence is trusted by millions of verified healthcare professionals to make high-stakes clinical decisions at the point of care with answers that are sourced, cited, and grounded in peer-reviewed medical literature. Founded with the mission to organize and expand the world's collective medical knowledge, OpenEvidence is actively used daily by the majority of physicians in the United States. OpenEvidence is free for all verified U.S. clinicians. AN OFFICIAL AI PARTNER OF: The New England Journal of Medicine (NEJM) The Journal of the American Medical Association (JAMA) and its 11 specialty journals National Comprehensive Cancer Network (NCCN) Nature Cochrane Library Wiley WHAT YOU GET: • Specific answers to clinical questions, with every claim cited to its source • 35 million+ peer-reviewed papers, 300+ medical journals, plus FDA and CDC sources • Licensed full text from NEJM, JAMA, Nature, Cochrane, and others • EvidenceGrade™: see the strength of the evidence behind every answer • CME and MOC credits, earned by asking questions • Visits for ambient documentation, Dialer for secure patient calls, and Voice Mode for hands-free answers CONTENT AGREEMENTS AND COLLABORATIONS: American Academy of Family Physicians (AAFP) American College of Cardiology (ACC) American Diabetes Association (ADA) American Academy of Pediatrics (AAP) American College of Obstetricians and Gynecologists (ACOG) American College of Emergency Physicians (ACEP) ASCO Guidelines American Academy of Orthopaedic Surgeons (AAOS) American Academy of Ophthalmology (AAO) American Urological Association (AUA) Plus AAO-HNS, GINA, SNO, SSO, and more. IN USE ACROSS: 10,000+ hospitals and medical centers nationwide, including Mayo Clinic, Mount Sinai, Cedars-Sinai, MSKCC, and Sutter Health. WHY CLINICIANS TRUST US: • HIPAA compliant across the platform • NEJM, JAMA, Nature, and NCCN—official content partners 
 • Tens of millions of clinical consultations per month WHAT CLINICIANS SAY: “OpenEvidence is currently the best AI tool for medical information.” — Dr. Paul Sax, Infectious Disease, Brigham and Women’s Hospital, Review in The New England Journal of Medicine Journal Watch (now NEJM Clinician) “In a morning report, a resident had a question that I didn’t know the answer to, but we were able to open OpenEvidence and get an answer on the spot.” — Dr. Kyle P. Lehenbauer, Minneapolis Veterans Affairs Medical Center “I use OpenEvidence multiple times during the day and every day. I am a better doc because of this. I expand my differential diagnoses and verify the science behind choices of treatments.” — Dr. Sharon E. Martin, Southern Huntingdon Medical Center Important note: OpenEvidence is available only to healthcare professionals. Users must verify their healthcare professional status before using OpenEvidence.