Comparison

CTCAE 6 Pro vs IOTOX Algorithm

Price, ratings, monetisation and update history for both apps, side by side — with what reviewers say about each.

Head to head
About

CTCAE 6 Pro

This app provides easy access to CTCAE 6.0 content, allowing users to bookmark adverse events, search for keywords, and organize notes. It offers features for version comparison, data export, and timeline management for premium subscribers.

Highlights
  • Quick CTCAE 6.0 content access
  • Unlimited bookmarking of adverse events
  • Keyword search with highlighting
  • Local data storage for privacy
  • Version comparison (5.0 vs 6.0)
  • Smart notes and chronological organization
  • Spreadsheet to custom list app conversion
Features
Read full description

CTCAE 6 Pro helps you review and take notes on CTCAE content with ease. It is not intended for diagnosis, clinical decisions, or treatment planning. Standard Features: • Quick CTCAE Access: Browse CTCAE 6.0 content with ease • Unlimited Flags: Bookmark AEs without limits • Search with Highlighting: Easily spot keywords in context • Local Data Storage: Keep your data secure and private on your device Premium Features (Subscription Users): • Version Comparison (5.0 ⇄ 6.0) • Smart Notes: Organize CTCAE entries chronologically, use hashtags, and more • Spreadsheet to App: Turn your spreadsheet into a custom list app—no coding required • Easy Backups: Export to XLSX or CSV for flexibility • Optimized Printing & Sharing: Export HTML files for instant viewing on any desktop or laptop, with easy letter-size printing • Timeline Management: Track and log AEs on a day-by-day basis

About

IOTOX Algorithm

This app provides clinical management algorithms for evaluating, diagnosing, and treating toxicities associated with cancer immunotherapies. It guides physicians on best practices for managing side effects that can arise during cancer treatment.

Highlights
  • Clinical management algorithms
  • Evaluation of toxicities
  • Diagnosis of side effects
  • Treatment of immunotherapy toxicities
  • Best practices for patient care
Features
Read full description

Immunotherapies have become essential in treating advanced malignancies. However, immunotherapies can attack healthy cells, leading to toxicities or side effects. To address how to best treat patients with these toxicities, the Internal Medicine division has collaborated with the Cancer Medicine division, as well as other divisions at MD Anderson, to create the Immuno-Oncology Toxicity (IOTOX) Leaders Group. ​​​​​​​ Clinical management algorithms depict best practices for evaluating, diagnosing, and treating specific conditions that arise during the course of cancer treatment. These algorithms are not intended to replace the independent medical judgment of the physician in the context of individual clinical circumstances to determine a patient's care.

Screenshots

CTCAE 6 Pro4 screens
IOTOX Algorithm4 screens

Verdict

The call

The clearest difference is in-app purchases: IOTOX Algorithm at none against CTCAE 6 Pro's 2. CTCAE 6 Pro's advantage is ratings volume (10 vs 1) and device support (3 vs 1). On price, rating, update cadence and ads there is nothing between them.

Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS

CostPrice · In-app purchases · Ads · Monetization

Both are free to download. CTCAE 6 Pro sells 2 in-app purchases, starting at $1.99 per month. IOTOX Algorithm asks for nothing beyond the download.

ReceptionRating · Positive reviews · Number of ratings

On the App Store both sit at effectively the same score — 5.0 for CTCAE 6 Pro against 5.0 for IOTOX Algorithm. That said, the two scores are not equally well evidenced: CTCAE 6 Pro has 10 ratings behind it against 1, so its average is the more settled of the two.

UpkeepUpdate frequency

CTCAE 6 Pro ships an update every 3 weeks, IOTOX Algorithm every 6 weeks. The most recent releases landed on October 30, 2026 and October 22, 2026 respectively.

Scorecard5 real differences · 4 level
CTCAE 6 Pro versus IOTOX Algorithm: the parameters behind the verdict, then further details
ParameterCTCAE 6 ProIOTOX Algorithm
PriceFreeFree
Rating5.0 (10 ratings)5.0 (1 ratings)
Number of ratings10 — better1
Update frequencyEvery 3 weeks — betterEvery 6 weeks
AdsNoNo
In-app purchasesYesNo — better
MonetizationFreemiumFree — better
DevicesiPhone, iPad, iPod — betteriPhone
Requires iOS15.6 — better18.0
Further details — not scored
Size87 MB7 MB
Age rating17+17+
DeveloperKoichiro WatanabeMD Anderson Cancer Center

Customer experience

CTCAE 6 Pro

All ratings10 ratings
Positive100.0%
Neutral0.0%
Negative0.0%

IOTOX Algorithm

All ratings1 ratings
Positive100.0%
Neutral0.0%
Negative0.0%

In-app purchases

2 purchases

CTCAE 6 Pro

Subscriptions2
  • Premium Plan – Monthly7 Days trial$1.991 Month
  • Premium Plan – Annual7 Days trial$9.991 Year
None

IOTOX Algorithm

No in-app purchases

Questions

Is CTCAE 6 Pro free?
CTCAE 6 Pro is free to download, with in-app purchases available.
Is IOTOX Algorithm free?
IOTOX Algorithm is free to download, with no in-app purchases.
Which has better reviews, CTCAE 6 Pro or IOTOX Algorithm?
CTCAE 6 Pro and IOTOX Algorithm are both rated 5.0 out of 5 on the App Store, from 10 and 1 ratings respectively.
Do CTCAE 6 Pro or IOTOX Algorithm have ads?
Neither CTCAE 6 Pro nor IOTOX Algorithm shows ads.
Which is updated more often, CTCAE 6 Pro or IOTOX Algorithm?
CTCAE 6 Pro ships an update every 3 weeks, and IOTOX Algorithm every 6 weeks. Most recently, CTCAE 6 Pro was updated on October 30, 2026 and IOTOX Algorithm on October 22, 2026.

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