Comparison

Drugle vs Total Biochem

Price, ratings, monetisation and update history for both games, side by side — with what reviewers say about each.

Head to head
About

Drugle

Guess the daily drug within eight attempts. Explore an unlimited mode for continuous play. This educational trivia game is for entertainment and knowledge testing only.

Highlights
  • Daily drug guessing
  • Eight guesses limit
  • Unlimited play mode
  • Educational trivia
  • Knowledge testing
Features
Read full description

You get eight guesses to guess the drug of the day! If you feel up to it you can play the unlimited mode ***This app is an educational tool and trivia game with no ability to diagnose or provide medical advice. Please contact a medical professional before making any medical decisions***

About

Total Biochem

Master biochemistry with comprehensive study tools, including practice questions, lessons, flashcards, and mock exams. Then, apply your knowledge in a captivating night-shift mystery game where you diagnose patients by analyzing lab results and biochemical pathways.

Highlights
  • 3,300+ Practice Items
  • Lessons for Every Topic
  • Flashcards & Cheat Sheets
  • Mock Exams & Course Map
  • Step-by-step Mechanism Walkthroughs
  • Clinical Mystery Game
  • Lab Analysis Simulation
Read full description

A complete biochemistry study app with a bonus night-shift mystery game. Drill every topic and read every pathway — then take a case on the metabolic service, where the same biochemistry is the only thing that tells you what's wrong with the patient. STUDY — EVERYTHING BEFORE THE EXAM (AND AFTER) • 3,300+ Practice Items: 37 drill topics from amino acids to metabolic integration — enzyme kinetics, the pathways, inborn errors, lab methods, the central dogma, and more. Built for course exams, MCAT review, and anyone coming back to biochemistry. • A Lesson for Every Topic: the rules, the traps, and figures drawn the way the exam draws them — kinetics plots and pathway boards you can actually read. • Flashcards & Cheat Sheets: 31 decks and 550+ cards with spaced review, plus pinned reference sheets — the pKa ladder, the control points, the compartments, the quick reference. • Mock Exams & the Course Map: build a practice test with pace presets and exam-style deferred feedback, fix what you missed, and clear units on the Course Map. • Mechanisms, Arrow by Arrow: 15 step-by-step walkthroughs — serine proteases, PLP, TPP, kinases, aldolases — one electron push at a time. PLAY — THE BONUS: A CLINICAL MYSTERY • Work the Night Service: seven floors of a hospital, from the nursery to the exercise lab. Patients arrive with a story — an infant who vomits after fruit juice, a runner with cola-colored urine — and your job is to find the enzyme that failed. • Read the Labs Yourself: order tests against a clock, a reagent budget, and one tube of blood that never refills. The instrument shows you the trace; it never tells you what it means. Misread it, and the wrong number goes in the file. • Place the Block: pin a block on one step of the pathway board and see what the body would do — what piles up, what runs out. When it matches the labs, you call the attending. Three answers, one phone call, no partial credit. • A Hospital with Secrets: every floor has its own story — a swapped formula lot, a visitor after hours, a signature from a clinic that closed last year. Look around, ask the right person, and find out. Free to try. One purchase unlocks everything — no subscriptions, no microtransactions.

Screenshots

Drugle4 screens
Total Biochem4 screens

Verdict

The call

The clearest difference is rating: Total Biochem at 5.0 against Drugle's 3.2. Total Biochem also leads on update cadence (weekly vs every 3 weeks). Drugle's advantage is ratings volume (5 vs 1). On price, ads, in-app purchases and monetization model there is nothing between them.

Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS

CostPrice · In-app purchases · Ads · Monetization

Both are free to download. Drugle sells 1 one-off in-app purchase and Total Biochem sells 1 one-off in-app purchase. Whichever you choose, the download price is not the number that matters.

ReceptionRating · Positive reviews · Number of ratings

Total Biochem holds the better App Store score, 5.0 against 3.2. That said, the two scores are not equally well evidenced: Drugle has 5 ratings behind it against 1, so its average is the more settled of the two.

UpkeepUpdate frequency

Drugle ships an update every 3 weeks, Total Biochem weekly. The most recent releases landed on October 11, 2026 and October 8, 2026 respectively.

Scorecard3 real differences · 7 level
Drugle versus Total Biochem: the parameters behind the verdict, then further details
ParameterDrugleTotal Biochem
PriceFreeFree
Rating3.2 (5 ratings)5.0 (1 ratings) — better
Positive reviews0.0% of reviews—
Number of ratings5 — better1
Update frequencyEvery 3 weeksWeekly — better
AdsNoNo
In-app purchasesYesYes
MonetizationFree with in-app purchasesFree with in-app purchases
DevicesiPhone, iPad, iPodiPhone, iPad, iPod
Requires iOS15.0 — better15.1
Further details — not scored
Size140 MB63 MB
Age rating4+4+
DeveloperGriffin SkaffSinter Labs LLC

Customer experience

Drugle

All ratings5 ratings
Positive40.0%
Neutral20.0%
Negative40.0%
Written reviews2 reviews
Positive0.0%
Neutral50.0%
Negative50.0%

Total Biochem

All ratings1 ratings
Positive100.0%
Neutral0.0%
Negative0.0%

In-app purchases

1 purchases

Drugle

One-time1
  • Remove Ads$1.99
1 purchases

Total Biochem

One-time1
  • Full Game$9.99

Questions

Is Drugle free?
Drugle is free to download, with in-app purchases available.
Is Total Biochem free?
Total Biochem is free to download, with in-app purchases available.
Which has better reviews, Drugle or Total Biochem?
Total Biochem is rated higher. Drugle averages 3.2 out of 5 from 5 ratings, while Total Biochem averages 5.0 from 1 ratings.
Do Drugle or Total Biochem have ads?
Neither Drugle nor Total Biochem shows ads.
Which is updated more often, Drugle or Total Biochem?
Drugle ships an update every 3 weeks, and Total Biochem weekly. Most recently, Drugle was updated on October 11, 2026 and Total Biochem on October 8, 2026.

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