Biosimilar vs Maudsley Deprescribing Guide

Biologic drugs offer important treatment options for patients suffering from auto-immune disorders such as rheumatoid arthritis and for common cancers including breast and colon. Biosimilar and interchangeable products, which can loosely be thought of as ‘generic’ biologics, are important for promoting competition and driving down costs. The FDA maintains a list of approved biosimilars in the Purple Book. The Biosimilar iOS app provides a handy reference to the Purple Book as well as important information related to prescribing and dispensing for clinicians and pharmacists navigating this complex area of drug therapeutics. ** Disclaimer ** - non-medical users should ask for a doctor’s advice in addition to using this app and before making any medical decisions.

"Try before you buy"-Download the FREE App,which includes sample content. In-App purchase required to unlock all content. The Maudsley Deprescribing Guidelines provide evidence-based recommendations for safely discontinuing antidepressants, benzodiazepines, gabapentinoids, and Z-drugs. This resource is essential for healthcare professionals aiming to optimize patient care and minimize medication-related harm. It emphasizes a patient-centered approach, ensuring that deprescribing is conducted thoughtfully and effectively. Most formal guidance on psychiatric medication relates to starting or switching medications with minimal guidance on deprescribing medication. In 2023, the World Health Organisation and the United Nations called for patients, as a human right, to be informed of their right to discontinue treatment and to receive support to do so. The Maudsley Deprescribing Guidelines fills a significant gap in guidance for clinicians by providing comprehensive and authoritative information on this important aspect of treatment. This evidence-based handbook provides an overview of principles to be used in deprescribing. This is derived from fundamental scientific principles and the latest research on this topic, combined with emerging insights from clinical practice (including from patient experts). Building on the recognised brand of The Maudsley Prescribing Guidelines, and the prominence of the authors’ work, including in The Lancet Psychiatry on tapering antidepressants (the most read article across all Lancet titles when it was released). The Maudsley Deprescribing Guidelines covers topics such as: - Why and when to deprescribe antidepressants, benzodiazepines, gabapentinoids and z-drugs - Barriers and enablers to deprescribing including physical dependence, social circumstances, and knowledge about the discontinuation process - Distinguishing withdrawal symptoms, such as poor mood, anxiety, insomnia, and a variety of physical symptoms from symptoms of the underlying disorder that medication was intended to treat - The difference between physical dependence and addiction/substance use disorder - Explanation of why and how to implement hyperbolic tapering in clinical practice - Specific guidance on formulations of medication and techniques for making gradual reductions, including using liquid forms of medication, and other approaches - Step-by-step guidance for safely stopping all commonly used antidepressants, benzodiazepines, gabapentinoids and z-drugs, including fast, moderate and slow tapering regimens or schedules for each drug, and guidance on how to tailor these to an individual - Troubleshooting issues which can arise on stopping these medications, including akathisia, withdrawal symptoms, acute or protracted, and relapse. - Written for anyone interested in safe deprescribing of psychiatric medications including psychiatrists, GPs, pharmacists, nurses, medical trainees, and interested members of the public. The Maudsley Deprescribing Guidelines is an essential resource on the subject that provides practical guidance on how to improve patient outcomes in this field of medicine. Disclaimer : App developers do not endorse or recommend any specific medications. Always consult a qualified healthcare provider before starting, changing, or stopping any medication. Content licensed from printed ISBN 10: 1119823021 Content licensed from printed ISBN 13: 9781119823025 If you have any questions or comments,email us any time:customersupport@skyscape.com or call 508-299-3000 Privacy Policy-https://www.skyscape.com/terms-of-service/privacypolicy.aspx Terms & Conditions-https://www.skyscape.com/terms-of-service/licenseagreement.aspx Author:Deanna Mark Horowitz; David M. Taylor Publisher:Wiley-Blackwell