TDF Calc vs ICCR

TDFCalc is an application which implements the linear-quadratic (LQ) method for comparing the biologically effective dose (BED) of external beam radiation therapy (EBRT) fractionation regimens as well as low dose rate (LDR) and permanent implant brachytherapy treatments. It calculates BED for a given alpha/beta ratio as a function of the dose per fraction and number of fractions for EBRT, and initial dose rate for brachytherapy. For a predetermined BED, the app solves the quadratic equation to calculate dose per fraction as a function of the number of fractions desired. This enables quick comparison of modified fractionation regimens (e.g. hypofractionation or compensating for missing treatment fractions) vs a conventional and/or originally intended regimen.

The Internal Contamination Clinical Reference app is a reference tool to be used for educational and informational purposes only. The app provides information about internal contamination with a number of radionuclides and their medical countermeasure. The app estimates reference concentrations of radionuclides in urine using standard biokinetics models and assuming intakes equal to one Clinical Decision Guide (CDG) for each radionuclide based on hypothetical patient scenarios. The intended audience for the app is clinicians, health physicists, radiation safety officers, medical and public health laboratory scientists, or any other professional interested in internal contamination with radioactive materials and their medical therapy. Some basic understanding of concepts behind internal contamination and internal dosimetry are required to fully benefit from this application. The Internal Contamination Clinical Reference app features: * Reference information on a particular radionuclide or a medical countermeasure * Users can perform assessments based on hypothetical patient scenarios with each assessment projecting a reference concentration of radionuclides in urine based on user input * The assessment can be saved, edited and shared For more information, please visit http://www.cdc.gov/nceh/radiation/ or email rsbinfo@cdc.gov. This app was developed and produced by the Centers for Disease Control and Prevention http://www.cdc.gov/ and Oak Ridge Institute for Science and Education (ORISE) http://www.orau.gov/orise.htm through an interagency agreement with the U.S. Department of Energy (DOE). ORISE is managed by Oak Ridge Associated Universities under DOE contract number DE-AC05-06OR23100.