Comparison

Medicine Central vs Huppert's Notes

Price, ratings, monetisation and update history for both apps, side by side — with what reviewers say about each.

Head to head
About

Medicine Central

This comprehensive medical reference app provides quick access to essential information on diagnoses, treatments, and drug details. It integrates multiple trusted resources, including clinical consults, drug guides, diagnostic tests, and PubMed access, for efficient point-of-care decision-making.

Highlights
  • Over 1,000 medical conditions with treatment recommendations
  • Comprehensive drug information for over 5,000 drugs
  • Differential diagnoses search by symptom or disease
  • Information on over 450 common laboratory tests
  • Full PubMed database search with visual exploration
  • Cross-linking between integrated resources
  • Full text search across all references
Features
Read full description

ABOUT MEDICINE CENTRAL Medicine Central is an integrated mobile and web reference built specifically for physicians, residents, students, and nurse practitioners that includes 5-Minute Clinical Consult, Davis’s Drug Guide, McGraw-Hill’s Diagnosaurus®, Pocket Guide to Diagnostic Tests, and PubMed access. With four trusted references, Medicine Central delivers comprehensive content on the essentials of diagnosis, treatment, and follow-up for more than 1,000 diseases and disorders in a quick-read format directly to the point of care. Included in Medicine Central: 5-MINUTE CLINICAL CONSULT 5-Minute Clinical Consult (5MCC) is a best-selling app that features details on over 1,000 medical conditions and 200 pediatric conditions with evidence-based treatment recommendations in a proven, rapid-access format. 5MCC also includes dermatology images, algorithms for step-by-step patient management, patient teaching points, and more. DAVIS’S DRUG GUIDE Davis’s Drug Guide is a 5-star app that delivers up-to-date, comprehensive, and practical information on over 5,000 trade name and generic drugs. This best-selling resource contains everything you need to provide premium care to your patients including information on dosing and administration, safety, interactions, and much more. MCGRAW-HILL’S DIAGNOSAURUS Diagnosaurus allows you to quickly search over 1,000 differential diagnoses by organ system, symptom, disease, or you can view all entries. The valuable "See Related DDx" feature within each listing helps you consider alternative diagnoses and quickly link to those entries. POCKET GUIDE TO DIAGNOSTIC TESTS Pocket Guide to Diagnostic Tests provides evidence-based information on the selection and interpretation of more than 450 common laboratory tests. This quick-reference tool includes laboratory tests, diagnostic imaging, therapeutic drug monitoring, microbiology tests, and the use of tests in differential diagnosis. Prime PubMed Quickly search the complete PubMed database on your smartphone and tablet. Results contain abstracts, citations, and links to available full text articles which can be easily shared with classmates and colleagues. Additionally, Prime PubMed Search contains a powerful, exclusive feature called Grapherence™ which delivers a new way to visually explore the interrelationship and relevance of medical literature. FEATURES • Cross Links for fast navigation between resources • Frequent updates and new editions when they’re published • Browse the full PubMed journal database • Citations and abstracts from the latest medical journals • Highlight and make notes within any entry • Full Text Search – find topics fast across all references • ‘Favorites’ for bookmarking important entries • Web access and updates for one year DRUG AND CONTENT UPDATES • After initial Medicine Central purchase you will receive updates for one year • After one year, you can purchase updates for an additional year, at the discounted rate of $99.99. If you do not choose to purchase, you can continue to use the product but will not receive updates. • This app will automatically renew annually at the current renewal rate ($99.99) and charged to your iTunes account at confirmation of purchase, unless auto-renew is turned off 24 hours prior to the conclusion of the one-year subscription period. • Subscriptions may be managed by the user and auto-renewal may be turned off by going to the user's Account Settings after purchase. Publishers: Wolters Kluwer; F.A. Davis; McGraw-Hill Powered by: Unbound Medicine Unbound Privacy Policy: www.unboundmedicine.com/privacy Unbound Terms of Use: https://www.unboundmedicine.com/end_user_license_agreement

About

Huppert's Notes

This app provides a concise outline of internal medicine topics, bridging pathophysiology and clinical medicine. It's designed for medical trainees to take notes, access high-yield diagrams, and understand concepts mechanistically. The app offers a yearly subscription for full content access and updates.

Highlights
  • Personal note-taking on chapters
  • Audio and text notes
  • Outline format for rapid access
  • Concise descriptions of medical conditions
  • Diagnostic and management pearls
  • High-yield diagrams and tables
Features
Read full description

"Try before you buy" - Download the FREE App, which includes sample content. In-App purchase required to unlock all content. Key Features: * Take personal notes on each chapter especially when you are in chalk talks with an attending, fellow, or resident. * Audio Notes * Text Notes * Upload videos and images coming soon Bridge the gap between pathophysiology and clinical medicine in a succinct outline of core internal medicine topics! Primarily intended for medical trainees, from medical students to internal medicine interns and residents. Originally created and road-tested by a resident and then updated by a team of resident authors, Huppert’s Notes succinctly organizes the foundational science covered early in medical school and the clinical approaches encountered in clerkships and beyond. This marriage of pathophysiology and clinical medicine provides a framework for how to approach internal medicine concepts mechanistically, rather than through memorization. Designed to serve as a framework for your learning in internal medicine. You’ll find concise descriptions of common medical conditions with diagnostic and management pearls, as well as high-yield diagrams and tables to emphasize key concepts. Covering all internal medicine subspecialties, each Huppert’s Notes chapter is organized in an intuitive and consistent outline format for rapid access: - Anatomy & Physiology - Diagnostics - Approaches & Chief Complaints - Diseases & Pathophysiology - Key Medications & Interventions - Key Clinical Trials & Publications Overview of systems covered: - Cardiology - Pulmonology - Critical Care Medicine - Gastroenterology - Endocrinology - Nephrology - Hematology and Oncology - Infectious Diseases - Rheumatology - General Medicine - Medicine in the outpatient setting along with health maintenance pearls - Dermatology - Neurology - Psychiatry ISBN 10: 1260470075 ISBN 13: 9781260470079 SUBSCRIPTION : Please purchase a yearly auto-renewing subscription to receive content access and available updates. Yearly auto-renewing payments- $41.99 Payment will be charged to your iTunes Account at confirmation of purchase. Subscription automatically renews unless auto-renew is turned off at least 24-hours before the end of the current period. Subscription may be managed by the user and auto-renewal can be disabled at any time by going to your device “Settings” and tapping “iTunes & App Store”. Any unused portion of a free trial period will be forfeited when you purchase a subscription, where applicable. If you have any questions or comments, email us any time: customersupport@skyscape.com or call 508-299-3000 Privacy Policy - https://www.skyscape.com/terms-of-service/privacypolicy.aspx Terms and Conditions - https://www.skyscape.com/terms-of-service/licenseagreement.aspx Author(s): Laura A. Huppert Publisher: The McGraw-Hill Companies, Inc.

Screenshots

Medicine Central4 screens
Huppert's Notes4 screens

Verdict

The call

The clearest difference is ads: Medicine Central at none against Huppert's Notes's shown. Medicine Central also leads on ratings volume (117 vs 17). Huppert's Notes's advantage is review sentiment (100% vs 69%) and iOS requirement (13.0 vs 15.0). On price, rating, update cadence and in-app purchases there is nothing between them.

Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS

CostPrice · In-app purchases · Ads · Monetization

Both are free to download. Medicine Central sells 2 in-app purchases, starting at $99.99 per year and Huppert's Notes sells 4 in-app purchases, starting at $24.99 per 6 months. Whichever you choose, the download price is not the number that matters.

ReceptionRating · Positive reviews · Number of ratings

On the App Store both sit at effectively the same score — 5.0 for Medicine Central against 4.9 for Huppert's Notes. That said, the two scores are not equally well evidenced: Medicine Central has 117 ratings behind it against 17, so its average is the more settled of the two. Written reviews are what separate them: 69% of Medicine Central's written reviews are positive against 100% of Huppert's Notes's.

UpkeepUpdate frequency

Both ship on a similar rhythm, roughly every 6 months. The most recent releases landed on October 15, 2026 and October 6, 2026 respectively.

Scorecard4 real differences · 6 level
Medicine Central versus Huppert's Notes: the parameters behind the verdict, then further details
ParameterMedicine CentralHuppert's Notes
PriceFreeFree
Rating5.0 (117 ratings) — better4.9 (17 ratings)
Positive reviews69.2% of reviews100.0% of reviews — better
Number of ratings117 — better17
Update frequencyEvery 6 monthsEvery 6 months
AdsNo — betterYes
In-app purchasesYesYes
MonetizationFree with in-app purchasesFree with in-app purchases
DevicesiPhone, iPad, iPodiPhone, iPad, iPod, Mac — better
Requires iOS15.013.0 — better
Further details — not scored
Size9 MB47 MB
Age rating17+17+
DeveloperUnbound Medicine, Inc.Skyscape Medpresso Inc

Customer experience

Medicine Central

All ratings117 ratings
Positive100.0%
Neutral0.0%
Negative0.0%
Written reviews26 reviews
Positive69.2%
Neutral19.2%
Negative11.5%

Huppert's Notes

All ratings17 ratings
Positive94.1%
Neutral5.9%
Negative0.0%
Written reviews1 reviews
Positive100.0%
Neutral0.0%
Negative0.0%

In-app purchases

2 purchases

Medicine Central

Subscriptions1
  • Medicine Central Renewal$99.991 Year
One-time1
  • Medicine Central$169.99
4 purchases

Huppert's Notes

Subscriptions3
  • Huppert's Notes 6 Month Sub.$24.996 Months
  • #1 Resource for IM Residency$36.991 Year
  • Huppert's Notes 1 Year Sub.$41.991 Year
One-time1
  • Huppert's Notes IM$39.99

Questions

Is Medicine Central free?
Medicine Central is free to download, with in-app purchases available.
Is Huppert's Notes free?
Huppert's Notes is free to download, with in-app purchases available.
Which has better reviews, Medicine Central or Huppert's Notes?
Medicine Central is rated higher. Medicine Central averages 5.0 out of 5 from 117 ratings, while Huppert's Notes averages 4.9 from 17 ratings.
Do Medicine Central or Huppert's Notes have ads?
Huppert's Notes shows ads; Medicine Central does not.
Which is updated more often, Medicine Central or Huppert's Notes?
Medicine Central ships an update every 6 months, and Huppert's Notes every 6 months. Most recently, Medicine Central was updated on October 15, 2026 and Huppert's Notes on October 6, 2026.

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