eGFR Calculators vs CVD Risk Estimator Plus

From the National Kidney Foundation (NKF), this application allows medical professionals to estimate kidney function using five separate eGFR calculators: - CKD-EPI Creatinine 2021 Equation (Preferred method) - Revised Bedside Schwartz Formula (For ages 1-17) - Cockcroft-Gault Formula - CKD-EPI Cystatin C 2012 Equation - CKD-EPI Creatinine - Cystatin C 2021 Equation Also includes information on: -Glomerular filtration rate (GFR) -Chronic kidney disease (CKD) -Clinical use on how to test, evaluate, and slow progression -Formulas The National Kidney Foundation is the leading organization in the U.S. dedicated to the awareness, prevention, and treatment of kidney disease for hundreds of thousands of healthcare professionals, millions of patients and their families, and tens of millions of Americans at risk. By supporting the National Kidney Foundation, you directly influence and positively impact the lives of those at risk for kidney disease, those living with chronic kidney disease, and those who care for and about them. Learn more at www.kidney.org 30 East 3rd Street New York, NY 10016 www.kidney.org 800-622-9010

This clinical decision-support app is intended for use by healthcare professionals and unifies two cardiovascular prevention tools: the 2013 ACC/AHA Pooled Cohort Equations (previously known as the ASCVD Risk Estimator) and the American Heart Association’s PREVENT™ Calculator. Combining traditional ASCVD risk modeling with modern cardiovascular-kidney-metabolic (CKM)-inclusive risk equations, CVD Risk Estimator Plus supports comprehensive, personalized cardiovascular disease (CVD) risk assessment and clinician-guided decision-making. The results and recommendations provided by this application are intended to inform but do not replace clinical judgment. Therapeutic options should be individualized and determined after discussion between the patient and their care provider. CVD Risk Estimator Plus computes risk estimates using: • 2013 ASCVD Pooled Cohort Equations (PCE), which calculate 10-year and lifetime risk of atherosclerotic cardiovascular disease using age, sex, race, blood pressure, cholesterol profile, diabetes status, and smoking status. • 2023 PREVENT™ Equations, which estimate 10- and 30-year risk for total CVD, ASCVD, and heart failure (HF), incorporating kidney and metabolic health measures such as BMI and estimated glomerular filtration rate (eGFR), and supporting optional predictors including urine albumin creatinine ratio (UACR), hemoglobin A1c (HbA1c), and social deprivation index (SDI). Clinicians can toggle between Pooled Cohort and PREVENT™ risk trajectories to support guideline-aligned prevention discussions. This clinical decision support app provides: • Risk category classification (low, borderline, intermediate, high). • Personalized guidance informed by published guidelines, including statin therapy considerations, lifestyle interventions, and risk-enhancing clinical factors. • Export functionality supporting print and email of results for documentation and patient communication. • Resources page with related tools and informational materials for clinicians and patients, including links to source guidelines and reference documents.