Pneumotox. vs OpenEvidence

Pneumotox®: The drug-induced/iatrogenic respiratory disease website & App. The companion website and App Cardiotox® cover drug-induced cardiotoxicity. By Philippe Camus MD. Professor (emeritus) - Board-certified in pulmonary medicine and cardiology,- Université Bourgone-Europe, Dijon, France. Pneumotox is an aid to the diagnosis and management of respiratory diseases and reactions suspected of being induced by drugs, chemicals, and of iatrogenic origin. Causality assessment and exact diagnosis are the full responsibility of the user. Pneumotox is designed to provide regularly-updated information on drugs causing pulmonary toxicity (>1,700 agents), patterns of involvement (>820) and bibliography (>10,700 as of August 2026) within a few minutes. That may be the crux in emergency situations. Yet, double-checking in and from other sources is indicated. Pneumotox rests on a bibliographic repository built since 1978, which amounts to >50,000 references overall, the vast majority of which is indexed in PubMed. All references were and are carefully reviewed for reliability and causality by the founder, then indexed under the corresponding drug or agent in Pneumotox. Pneumotox can be assessed by causative drug(s), chemicals, herbals, substances of abuse, inhaled incl. e-cigarettes, vaping, inhalants, gases, ionizing radiations (providing the list of patterns), or by patterns of involvement (providing the list of causal drugs/agents). Drug names are generic (International Nonproprietary Names (INN), alphabetical), not brand ones. It may be appropriate to check the exact composition of any proprietary drug, as any other added substance or excipient can be pneumotoxic. Matching generic and brand names which differs with country is the responsibility of the user. Patterns are grouped by families according to the main anatomic site of involvement. If a drug or drug reaction is listed in Pneumotox, that does not equate the patient is demonstrating toxicity. A “Diagnosing DIRD” window in Pneumotox (top panel) may help secure the diagnosis. Lack of case or cases in the literature or in Pneumotox does not exclude a diagnosis of drug toxicity as there may be unpublished cases, you may be seeing the first case ever, or we may have overlooked some information. In such situations, please inform us; Pneumotox cannot be held responsible. Pneumotox can be contacted by mail 7/365 for complementary information, tailored literature, and/or data on rechallenge with the drug. In any patient, particularly the ones with acute respiratory failure, ARDS or acute bronchospasm, exposure to drugs, substances, and/or chemicals must be done exhaustively with the patient, and if needed with the family, health professionals, pharmacy and/or law enforcement personel. And prompt removal of the drug can be lifesaving. Caution: drug withdrawal can produce a flare of the underlying condition for which the drug was exactly given. Deliberate rechallenge can be hazardous as fatal relapse of the respiratiory reaction can supervene. Early sampling of body fluids for drug and/or metabolites is indicated as early as possible, particularly in the severely ill. Knowledge of toxidromes and antidotes capable of countering adverse effects of drugs or chemicals is essential (ex: PMID ). Where in doubt, consider double-checking PubMed, your affiliated Safety for Medicines Department/Agency and the Pharmacovigilance Department of drug companies. They may host more and/or undisclosed information. Patients should be reassured as such incidents are rare oveall. If needed, they are invited to consult with their treating physicians. Monitoring common causal agents (with red digits in stars) for impending toxicity is strongly advised. You may contact Pneumotox anytime through the contact window. ALL RIGHTS RESERVED The current version of Pneumotox website and App were developed by Akyos Communication Dijon France, under the guidance of Philippe Camus MD

Clinical Decision Support & Medical Search Engine for Healthcare Professionals (NPI Required) OpenEvidence is the most widely used clinical decision support platform and medical search engine among U.S. clinicians. According to independent studies, more American physicians use OpenEvidence than all other AI platforms combined. OpenEvidence is trusted by millions of verified healthcare professionals to make high-stakes clinical decisions at the point of care with answers that are sourced, cited, and grounded in peer-reviewed medical literature. Founded with the mission to organize and expand the world's collective medical knowledge, OpenEvidence is actively used daily by the majority of physicians in the United States. OpenEvidence is free for all verified U.S. clinicians. AN OFFICIAL AI PARTNER OF: The New England Journal of Medicine (NEJM) The Journal of the American Medical Association (JAMA) and its 11 specialty journals National Comprehensive Cancer Network (NCCN) Nature Cochrane Library Wiley WHAT YOU GET: • Specific answers to clinical questions, with every claim cited to its source • 35 million+ peer-reviewed papers, 300+ medical journals, plus FDA and CDC sources • Licensed full text from NEJM, JAMA, Nature, Cochrane, and others • EvidenceGrade™: see the strength of the evidence behind every answer • CME and MOC credits, earned by asking questions • Visits for ambient documentation, Dialer for secure patient calls, and Voice Mode for hands-free answers CONTENT AGREEMENTS AND COLLABORATIONS: American Academy of Family Physicians (AAFP) American College of Cardiology (ACC) American Diabetes Association (ADA) American Academy of Pediatrics (AAP) American College of Obstetricians and Gynecologists (ACOG) American College of Emergency Physicians (ACEP) ASCO Guidelines American Academy of Orthopaedic Surgeons (AAOS) American Academy of Ophthalmology (AAO) American Urological Association (AUA) Plus AAO-HNS, GINA, SNO, SSO, and more. IN USE ACROSS: 10,000+ hospitals and medical centers nationwide, including Mayo Clinic, Mount Sinai, Cedars-Sinai, MSKCC, and Sutter Health. WHY CLINICIANS TRUST US: • HIPAA compliant across the platform • NEJM, JAMA, Nature, and NCCN—official content partners 
 • Tens of millions of clinical consultations per month WHAT CLINICIANS SAY: “OpenEvidence is currently the best AI tool for medical information.” — Dr. Paul Sax, Infectious Disease, Brigham and Women’s Hospital, Review in The New England Journal of Medicine Journal Watch (now NEJM Clinician) “In a morning report, a resident had a question that I didn’t know the answer to, but we were able to open OpenEvidence and get an answer on the spot.” — Dr. Kyle P. Lehenbauer, Minneapolis Veterans Affairs Medical Center “I use OpenEvidence multiple times during the day and every day. I am a better doc because of this. I expand my differential diagnoses and verify the science behind choices of treatments.” — Dr. Sharon E. Martin, Southern Huntingdon Medical Center Important note: OpenEvidence is available only to healthcare professionals. Users must verify their healthcare professional status before using OpenEvidence.