iElastance vs VentilO

iElastance is an application designed for calculate Ventricular Elastance, Arterial Elastance and Ventricular-Arterial Coupling using Echocardiographic derived values in a single beat determination. This application is extremely useful to a variety of health care givers such as Cardiologists, Intensivists, Anesthesiologist and more who want to calculate ventricular arterial coupling even in the Critical Care setting and, above all, bedside. The variables needed for the calculator to work are: Systolic Blood Pressure (mmHg) Diastolic Blood Pressure (mmHg) Stroke Volume (ml) Ejection Fraction (%) Pre Ejection Time (msec) Total Ejection Time (msec) Formulas are validated and extracted from the article by Chen CH et Al J Am Coll Cardiol. 2001 Dec;38(7):2028-34. DISCLAIMER: The calculator provided is not meant to be a substitute for professional advice and is not to be used for medical diagnosis. Extensive effort has been exerted to make this software as accurate as possible; however the accuracy of information provided by this software cannot be guaranteed. Health care professionals should use clinical judjement and individualize therapy to each patient care situation. All rights reserved - 2024 Pietro Bertini

The VentilO application is a mobile educational application that allows healthcare professionals in charge of patients with mechanical ventilation: (i) to learn how to set the initial ventilatory settings in volume-controlled ventilation mode based on several parameters, (ii) to reason about the influence of different parameters on ventilatory needs in adult patients, (iii) to learn about optimization of ventilator settings for oxygenation, lung protection and CO2 elimination (iv) to learn about the impact of dead space on ventilation efficiency. The initial settings for minute ventilation (tidal volume (VT) and respiratory rate (RR)) will be proposed. The VT will be determined according to the predicted body weight, the body temperature and the type of patient (medical or surgical). VT/RR combinations for different targets of VT (3 to 10 mL / kg PBW will be provided, settings from 6 to 8 mL/kg PBW will be preferred). Educational texts are proposed to help other settings (PEEP and FiO2) in the different care contexts. ‘’Optimizing settings’’ is covered in another separate tab. Will provide calculation of several parameters (alveolar ventilation, dead space…) based on the patient’s data, ventilator settings and arterial blood gases results. In addition interpretations will be provided for Oxygenation, Ventilation (CO2) and Lung protection. In another separate tab ‘’Tools&Calculators’’, several tools are provided: -Impact of the instrumental is explained in details. Minute ventilation and alveolar ventilation (minute ventilation - dead space ventilation) are calculated. The physiological dead space is calculated according to published formulas linked to the predicted body weight of the patients, the instrumental dead space (linked to the volumes of the endotracheal tubes, connections, heat and moisture exchangers) is calculated. The impact of reducing dead space on several parameters is calculated (gain in alveolar ventilation, gain in reduction in tidal volume (and associated reduction in plateau pressure),or respiratory rate with constant alveolar ventilation) - Different Calculators (P/F ratio from SpO2, PBW…) -Links to several additional tools (Quick Reference Respiratory Care Card; O2 demand calculator, Recruitment to Inflation Ratio…) In addition to the measurements of these different parameters, several educational texts are accessible in the application to understand what dead space is during mechanical ventilation, what is instrumental dead space, what is the impact of dead space in function of ventilation settings and possible gains. These calculations and descriptions concern ventilated adult patients, in the emergency room, intensive care units and in the operating room. The VentilO application was developed with the help of several mechanical ventilation experts. The mobile application is trilingual (English, French and Spanish), based on the users settings.