Comparison

STI Tx Guide vs Syphilis Tools

Price, ratings, monetisation and update history for both apps, side by side — with what reviewers say about each.

Head to head
About

STI Tx Guide

Provides healthcare professionals with up-to-date, evidence-based recommendations for the prevention, diagnosis, and treatment of sexually transmitted infections. Features include clinical care guidance, sexual history resources, and patient materials for effective patient management.

Highlights
  • STI prevention recommendations
  • Diagnosis guidance
  • Treatment protocols
  • Clinical care assistance
  • Sexual history resources
  • Patient management tools
Features
Read full description

The new app offers quick and easy access to streamlined STI prevention, diagnosis, and treatment recommendations. The user-friendly interface includes more clinical care guidance, sexual history resources, patient materials, and other features to assist with patient management. The STI Treatment (Tx) Guidelines mobile app serves as a quick reference guide for doctors and related parties on the identification of and treatment for sexually transmitted diseases (STDs). The full STI Treatment Guidelines (cdc.gov) can be accessed at https://www.cdc.gov/std/treatment-guidelines/default.htm. The guidelines provide current evidence-based prevention, diagnostic and treatment recommendations that replace the 2015 guidance. The recommendations are intended to be a source for clinical guidance. Healthcare providers should always assess patients based on their clinical circumstances and local burden. DISCLAIMER THE MATERIALS EMBODIED IN THIS SOFTWARE IS PROVIDED TO YOU "AS-IS" AND WITHOUT WARRANTY OF ANY KIND, EXPRESS, IMPLIED OR OTHERWISE, INCLUDING WITHOUT LIMITATION, ANY WARRANTY OF FITNESS FOR A PARTICULAR PURPOSE. IN NO EVENT SHALL THE CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC) OR THE UNITED STATES (U.S.) GOVERNMENT BE LIABLE TO YOU OR ANYONE ELSE FOR ANY DIRECT, SPECIAL, INCIDENTAL, INDIRECT OR CONSEQUENTIAL DAMAGES OF ANY KIND, OR ANY DAMAGES WHATSOEVER, INCLUDING WITHOUT LIMITATION, LOSS OF PROFIT, LOSE OF USE, SAVINGS OR REVENUE, OR THE CLAIMS OF THIRD PARTIES, WHETHER OR NOT CDC OR THE U.S. GOVERNMENT HAS BEEN ADVISED OF THE POSSIBILITY OF SUCH LOSS, HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, ARISING OUT OF OR IN CONNECTION WITH THE POSSESSION, USE OR PERFORMANCE OF THIS SOFTWARE.

About

Syphilis Tools

This medical reference app provides healthcare professionals and trainees with up-to-date information on diagnosing, treating, and preventing syphilis. It includes tools for screening, serologic testing, staging, treatment, monitoring, and partner management, all based on CDC guidelines.

Highlights
  • CDC STI Treatment Guidelines
  • Offline accessibility
  • Geographic Risk Tool
  • Serologic Testing Interpretation
  • Nontreponemal Titer Tool
  • Treatment Regimen Summaries
  • Partner Management Guidance
Features
Read full description

The Syphilis Tools application is designed to give health care professionals, public health workers, and medical trainees relevant information and tools to help diagnose, treat, and prevent syphilis. Content is based on CDC STI Treatment Guidelines. It was developed for the National STD Curriculum (NSTDC) by the University of Washington Infectious Diseases Education & Assessment (IDEA) Program. The application addresses six primary areas: Screening: Information on screening recommendations for various patient populations. The Geographic Risk Tool allows users to quickly find county-level rates of primary and secondary syphilis in the United States and view syphilis screening recommendations. Serologic Testing: Users learn about the variety of tests and how to choose the appropriate test to order; interpret serologic tests results; and test cerebrospinal fluid. Reference materials for interpreting traditional and reverse syphilis screening algorithms are available. To help explain syphilis in a person with prior treatment, the Nontreponemal Titer Tool compares pretreatment and current treatment RPR or VDRL titers and interprets the results. Staging: Clinical criteria for understanding primary, secondary, latent, and tertiary syphilis and how to stage a patient. To help identify different manifestations, scientifically accurate medical illustrations are embedded in various sections. Treatment: Educational summaries of guideline-based medication regimens to treat stages and types of syphilis. How to treat individuals who are penicillin-allergic and/or pregnant are also addressed. Users can select multiple stages and types to explore the potential impacts on possible treatment regimens. Monitoring: Reference information on evaluating serologic response and titer changes. Users can select RPR or VDRL titers and review possible test interpretations via the Nontreponemal Titer Tool. Partner Management: Educational materials and guidance regarding the management of symptomatic and asymptomatic partners of persons diagnosed with syphilis. Features: • Content based directly on CDC STI Treatment Guidelines • Offline accessibility for use in environments without internet connection • Plain-text summaries and reference materials • Tools to help determine county-base geographic risk and compare changes in titers before and during treatment The application links to the National Network of STD Clinical Consultation Service which provides consultations for licensed healthcare professionals and STD program staff. ############### Medical Disclaimer ############### Syphilis Tools is an educational reference for health care providers. It is not a substitute for professional medical advice. Any person using this app should seek the advice of a physician or other qualified health care provider in addition to using this app before making any medical decisions.

Screenshots

STI Tx Guide4 screens
Syphilis Tools4 screens

Verdict

The call

The clearest difference is review sentiment: Syphilis Tools at 100% against STI Tx Guide's 36%. Syphilis Tools also leads on rating (4.5 vs 3.5) and update cadence (every 11 days vs every 2 months). STI Tx Guide's advantage is ratings volume (36 vs 2). On price, ads, in-app purchases and monetization model there is nothing between them.

Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS

CostPrice · In-app purchases · Ads · Monetization

Both are free to download. Neither carries in-app purchases, so what you see is what you pay.

ReceptionRating · Positive reviews · Number of ratings

Syphilis Tools holds the better App Store score, 4.5 against 3.5. That said, the two scores are not equally well evidenced: STI Tx Guide has 36 ratings behind it against 2, so its average is the more settled of the two. Written reviews point the same way: 36% of STI Tx Guide's written reviews are positive against 100% of Syphilis Tools's.

UpkeepUpdate frequency

STI Tx Guide ships an update every 2 months, Syphilis Tools every 11 days. The most recent releases landed on October 8, 2026 and October 16, 2026 respectively.

Scorecard4 real differences · 6 level
STI Tx Guide versus Syphilis Tools: the parameters behind the verdict, then further details
ParameterSTI Tx GuideSyphilis Tools
PriceFreeFree
Rating3.5 (36 ratings)4.5 (2 ratings) — better
Positive reviews35.7% of reviews100.0% of reviews — better
Number of ratings36 — better2
Update frequencyEvery 2 monthsEvery 11 days — better
AdsNoNo
In-app purchasesNoNo
MonetizationFreeFree
DevicesiPhone, iPodiPhone, iPad, iPod — better
Requires iOS15.015.0.0
Further details — not scored
Size36 MB57 MB
Age rating12+17+
DeveloperCenters For Disease Control and PreventionUniversity Of Washington

Customer experience

STI Tx Guide

All ratings36 ratings
Positive63.9%
Neutral2.8%
Negative33.3%
Written reviews14 reviews
Positive35.7%
Neutral7.1%
Negative57.1%

Syphilis Tools

All ratings2 ratings
Positive100.0%
Neutral0.0%
Negative0.0%
Written reviews1 reviews
Positive100.0%
Neutral0.0%
Negative0.0%

In-app purchases

None

STI Tx Guide

No in-app purchases

None

Syphilis Tools

No in-app purchases

Questions

Is STI Tx Guide free?
STI Tx Guide is free to download, with no in-app purchases.
Is Syphilis Tools free?
Syphilis Tools is free to download, with no in-app purchases.
Which has better reviews, STI Tx Guide or Syphilis Tools?
Syphilis Tools is rated higher. STI Tx Guide averages 3.5 out of 5 from 36 ratings, while Syphilis Tools averages 4.5 from 2 ratings.
Do STI Tx Guide or Syphilis Tools have ads?
Neither STI Tx Guide nor Syphilis Tools shows ads.
Which is updated more often, STI Tx Guide or Syphilis Tools?
STI Tx Guide ships an update every 2 months, and Syphilis Tools every 11 days. Most recently, STI Tx Guide was updated on October 8, 2026 and Syphilis Tools on October 16, 2026.

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