Comparison

STI Tx Guide vs Guideline Central

Price, ratings, monetisation and update history for both apps, side by side — with what reviewers say about each.

Head to head
About

STI Tx Guide

Provides healthcare professionals with up-to-date, evidence-based recommendations for the prevention, diagnosis, and treatment of sexually transmitted infections. Features include clinical care guidance, sexual history resources, and patient materials for effective patient management.

Highlights
  • STI prevention recommendations
  • Diagnosis guidance
  • Treatment protocols
  • Clinical care assistance
  • Sexual history resources
  • Patient management tools
Features
Read full description

The new app offers quick and easy access to streamlined STI prevention, diagnosis, and treatment recommendations. The user-friendly interface includes more clinical care guidance, sexual history resources, patient materials, and other features to assist with patient management. The STI Treatment (Tx) Guidelines mobile app serves as a quick reference guide for doctors and related parties on the identification of and treatment for sexually transmitted diseases (STDs). The full STI Treatment Guidelines (cdc.gov) can be accessed at https://www.cdc.gov/std/treatment-guidelines/default.htm. The guidelines provide current evidence-based prevention, diagnostic and treatment recommendations that replace the 2015 guidance. The recommendations are intended to be a source for clinical guidance. Healthcare providers should always assess patients based on their clinical circumstances and local burden. DISCLAIMER THE MATERIALS EMBODIED IN THIS SOFTWARE IS PROVIDED TO YOU "AS-IS" AND WITHOUT WARRANTY OF ANY KIND, EXPRESS, IMPLIED OR OTHERWISE, INCLUDING WITHOUT LIMITATION, ANY WARRANTY OF FITNESS FOR A PARTICULAR PURPOSE. IN NO EVENT SHALL THE CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC) OR THE UNITED STATES (U.S.) GOVERNMENT BE LIABLE TO YOU OR ANYONE ELSE FOR ANY DIRECT, SPECIAL, INCIDENTAL, INDIRECT OR CONSEQUENTIAL DAMAGES OF ANY KIND, OR ANY DAMAGES WHATSOEVER, INCLUDING WITHOUT LIMITATION, LOSS OF PROFIT, LOSE OF USE, SAVINGS OR REVENUE, OR THE CLAIMS OF THIRD PARTIES, WHETHER OR NOT CDC OR THE U.S. GOVERNMENT HAS BEEN ADVISED OF THE POSSIBILITY OF SUCH LOSS, HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, ARISING OUT OF OR IN CONNECTION WITH THE POSSESSION, USE OR PERFORMANCE OF THIS SOFTWARE.

About

Guideline Central

Access a vast collection of clinical practice guidelines and decision-support tools. Quickly find recommendations, calculators, drug information, and more to improve patient care. Stay updated with the latest medical research and guidelines from global associations.

Highlights
  • Clinical practice guideline repository
  • Guideline summaries and full text links
  • Clinical calculators
  • Drug monographs
  • Clinical trials search
  • Preventive services recommendations
  • PubMed search integration
Features
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Guideline Central is the world’s largest repository of clinical practice guidelines, and it can now be easily accessed in the updated Guideline Central App. Choose from medical guidelines and other clinical decision-support tools to gain quick access to critical resources and guideline recommendations that help improve patient outcomes. Choose from nearly 4,000 official medical association guidelines representing all of the main medical specialties and therapeutic areas, and from societies in the USA, Europe, Canada, UK, Australia, and more. These are official society guidelines, gathered and condensed into a quick reference format that is current, practical and portable. The Guideline Central app offers over 2,700 guideline summaries, as well as 500+ premium pocket guides that were developed with authoring medical associations. In addition to clinical practice guidelines, the app also includes other frequently used clinical reference resources. Our Clinical quick reference tools include: * Guideline Summaries: Quick-access to the graded recommendations from thousands of clinical practice guidelines, along with meta-data and links to the full text guideline on the society journal or website. * Quizzes & CME Activities: Guidelines-based quizzes, and thousands of free online CME activities * Clinical Calculators: 150+ mobile optimized clinical calculators such as ASVCD risk, HAS-BLED and more * Drug Monographs: Up to date medication information, including dosing, contraindications, and more * Clinical Trials: Search for ongoing clinical trials, or for posted results from phase 3 and phase 4 clinical trials that have been completed * Preventive Services:  Get the most updated USPSTF preventive service recommendations in a convenient interface * PubMed Search: Mobile optimized search of the world's largest abstract and citation database with searchable index of biomedical literature from MEDLINE and PubMed * Guideline InSights: The official GC hub comparing guidelines on the same topic, covering changes in guidelines over time, and much more Some of the critical features of the Guideline Central App are: * Key recommendations, as well as algorithms, figures, and tables * Find within content and search across sources * Recommendation filtering based on grade and more * Updates when new guidelines are released * Ability to sign up to be notified of new guidelines for your specialty, or from specific associations * Share, store and take notes for frequently accessed guidelines * And much more   Download the Guideline Central App to get access to clinical practice guideline database which meets a variety of clinical guideline information for the purposes of: * Quick refresher on latest guidelines * Point of care clinical reference for physicians, nurses, pharmacists and more * Clinical decision support * For students or residents in schools or hospital settings * And more CUSTOMER SUPPORT * Guideline Central customer support is available to help get the app up and running in short time in case of any technical issues. Societies or institutions who are interested in having their guidelines included withing our platform are welcome to reach us out any time * Contact us via email at info at guidelinecentral dot com * Contact us via telephone at 1-407-878-7606 M-T 8am-4pm ET (US) Terms of Use: https://www.guidelinecentral.com/mobile-terms-of-use/

Screenshots

STI Tx Guide4 screens
Guideline Central4 screens

Verdict

The call

The clearest difference is review sentiment: Guideline Central at 100% against STI Tx Guide's 36%. Guideline Central also leads on rating (5.0 vs 3.5) and update cadence (every 2 weeks vs every 2 months). STI Tx Guide's advantage is ratings volume (36 vs 2). On price, ads, in-app purchases and monetization model there is nothing between them.

Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS

CostPrice · In-app purchases · Ads · Monetization

Both are free to download. Neither carries in-app purchases, so what you see is what you pay.

ReceptionRating · Positive reviews · Number of ratings

Guideline Central holds the better App Store score, 5.0 against 3.5. That said, the two scores are not equally well evidenced: STI Tx Guide has 36 ratings behind it against 2, so its average is the more settled of the two. Written reviews point the same way: 36% of STI Tx Guide's written reviews are positive against 100% of Guideline Central's.

UpkeepUpdate frequency

STI Tx Guide ships an update every 2 months, Guideline Central every 2 weeks. The most recent releases landed on October 8, 2026 and October 16, 2026 respectively.

Scorecard4 real differences · 6 level
STI Tx Guide versus Guideline Central: the parameters behind the verdict, then further details
ParameterSTI Tx GuideGuideline Central
PriceFreeFree
Rating3.5 (36 ratings)5.0 (2 ratings) — better
Positive reviews35.7% of reviews100.0% of reviews — better
Number of ratings36 — better2
Update frequencyEvery 2 monthsEvery 2 weeks — better
AdsNoNo
In-app purchasesNoNo
MonetizationFreeFree
DevicesiPhone, iPodiPhone, iPad, iPod — better
Requires iOS15.0 — better15.1
Further details — not scored
Size36 MB36 MB
Age rating12+17+
DeveloperCenters For Disease Control and PreventionInternational Guidelines Center, Inc

Customer experience

STI Tx Guide

All ratings36 ratings
Positive63.9%
Neutral2.8%
Negative33.3%
Written reviews14 reviews
Positive35.7%
Neutral7.1%
Negative57.1%

Guideline Central

All ratings2 ratings
Positive100.0%
Neutral0.0%
Negative0.0%
Written reviews2 reviews
Positive100.0%
Neutral0.0%
Negative0.0%

In-app purchases

None

STI Tx Guide

No in-app purchases

None

Guideline Central

No in-app purchases

Questions

Is STI Tx Guide free?
STI Tx Guide is free to download, with no in-app purchases.
Is Guideline Central free?
Guideline Central is free to download, with no in-app purchases.
Which has better reviews, STI Tx Guide or Guideline Central?
Guideline Central is rated higher. STI Tx Guide averages 3.5 out of 5 from 36 ratings, while Guideline Central averages 5.0 from 2 ratings.
Do STI Tx Guide or Guideline Central have ads?
Neither STI Tx Guide nor Guideline Central shows ads.
Which is updated more often, STI Tx Guide or Guideline Central?
STI Tx Guide ships an update every 2 months, and Guideline Central every 2 weeks. Most recently, STI Tx Guide was updated on October 8, 2026 and Guideline Central on October 16, 2026.

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