ACP MKSAP vs Guideline Central
Price, ratings, monetisation and update history for both apps, side by side — with what reviewers say about each.
ACP MKSAP
Access comprehensive internal medicine knowledge and practice exam-style questions offline. This app syncs your progress with the online version when connected to the internet. It's designed for physicians to stay updated on the latest evidence and enhance their clinical decision-making skills.
- Offline access to text and questions
- Thousands of exam-like multiple-choice questions
- Patient-based clinical scenarios
- Syncs progress with online version
- Includes figures, charts, and tables
- Targets knowledge gaps
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This app supplements the online version and is included with your ACP MKSAP subscription. Simply log in with your ACP or ACP MKSAP username and password. If you need assistance setting up your account, visit ACP Online. Some functionality within the app requires an active Internet connection. Your suggestions for future updates and enhanced features are welcome at mksap_editors@acponline.org. The new ACP Medical Knowledge Self-Assessment Program℠ (ACP MKSAP℠) provides you with the most current and critical information in the core of internal medicine and its subspecialties so you can stay aware of what you need to know as a practicing physician in internal medicine today. ACP MKSAP consists of well-researched text sections and thousands of exam-like multiple-choice questions along with hundreds of figures, charts, and tables to enhance your learning experience. ACP MKSAP's original, high-quality questions comprise patient-based clinical scenarios based on the latest evidence. Each question will challenge your decision-making, help you discover areas of strength, and target areas for you to update or acquire new knowledge. This app enables ACP MKSAP subscribers to read all of the text and answer all of the questions offline. When you are connected to the Internet, answers will sync automatically with the online version. The publisher of this app, the American College of Physicians, is the largest medical specialty organization in the United States with members in more than 145 countries worldwide. ACP membership includes 161,000 internal medicine physicians (internists), related subspecialists, and medical students. Internal medicine physicians are specialists who apply scientific knowledge and clinical expertise to the diagnosis, treatment, and compassionate care of adults across the spectrum from health to complex illness. Subscriber License Agreement: https://mksap.acponline.org/license
Guideline Central
Access a vast collection of clinical practice guidelines and decision-support tools. Quickly find recommendations, calculators, drug information, and more to improve patient care. Stay updated with the latest medical research and guidelines from global associations.
- Clinical practice guideline repository
- Guideline summaries and full text links
- Clinical calculators
- Drug monographs
- Clinical trials search
- Preventive services recommendations
- PubMed search integration
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Guideline Central is the world’s largest repository of clinical practice guidelines, and it can now be easily accessed in the updated Guideline Central App. Choose from medical guidelines and other clinical decision-support tools to gain quick access to critical resources and guideline recommendations that help improve patient outcomes. Choose from nearly 4,000 official medical association guidelines representing all of the main medical specialties and therapeutic areas, and from societies in the USA, Europe, Canada, UK, Australia, and more. These are official society guidelines, gathered and condensed into a quick reference format that is current, practical and portable. The Guideline Central app offers over 2,700 guideline summaries, as well as 500+ premium pocket guides that were developed with authoring medical associations. In addition to clinical practice guidelines, the app also includes other frequently used clinical reference resources. Our Clinical quick reference tools include: * Guideline Summaries: Quick-access to the graded recommendations from thousands of clinical practice guidelines, along with meta-data and links to the full text guideline on the society journal or website. * Quizzes & CME Activities: Guidelines-based quizzes, and thousands of free online CME activities * Clinical Calculators: 150+ mobile optimized clinical calculators such as ASVCD risk, HAS-BLED and more * Drug Monographs: Up to date medication information, including dosing, contraindications, and more * Clinical Trials: Search for ongoing clinical trials, or for posted results from phase 3 and phase 4 clinical trials that have been completed * Preventive Services: Get the most updated USPSTF preventive service recommendations in a convenient interface * PubMed Search: Mobile optimized search of the world's largest abstract and citation database with searchable index of biomedical literature from MEDLINE and PubMed * Guideline InSights: The official GC hub comparing guidelines on the same topic, covering changes in guidelines over time, and much more Some of the critical features of the Guideline Central App are: * Key recommendations, as well as algorithms, figures, and tables * Find within content and search across sources * Recommendation filtering based on grade and more * Updates when new guidelines are released * Ability to sign up to be notified of new guidelines for your specialty, or from specific associations * Share, store and take notes for frequently accessed guidelines * And much more Download the Guideline Central App to get access to clinical practice guideline database which meets a variety of clinical guideline information for the purposes of: * Quick refresher on latest guidelines * Point of care clinical reference for physicians, nurses, pharmacists and more * Clinical decision support * For students or residents in schools or hospital settings * And more CUSTOMER SUPPORT * Guideline Central customer support is available to help get the app up and running in short time in case of any technical issues. Societies or institutions who are interested in having their guidelines included withing our platform are welcome to reach us out any time * Contact us via email at info at guidelinecentral dot com * Contact us via telephone at 1-407-878-7606 M-T 8am-4pm ET (US) Terms of Use: https://www.guidelinecentral.com/mobile-terms-of-use/
Screenshots
Verdict
The clearest difference is review sentiment: Guideline Central at 100% against ACP MKSAP's 57%. Guideline Central also leads on rating (5.0 vs 4.2) and in-app purchases (none vs 1). ACP MKSAP's advantage is ratings volume (16 vs 2) and iOS requirement (13.0 vs 15.1). On price, update cadence, ads and device support there is nothing between them.
Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS
Both are free to download. ACP MKSAP sells 1 in-app purchase, starting at $999.99 per year. Guideline Central asks for nothing beyond the download.
Guideline Central holds the better App Store score, 5.0 against 4.2. That said, the two scores are not equally well evidenced: ACP MKSAP has 16 ratings behind it against 2, so its average is the more settled of the two. Written reviews point the same way: 57% of ACP MKSAP's written reviews are positive against 100% of Guideline Central's.
ACP MKSAP ships an update every 10 days, Guideline Central every 2 weeks. The most recent releases landed on October 21, 2026 and October 24, 2026 respectively.
| Parameter | ACP MKSAP | Guideline Central |
|---|---|---|
| Price | Free | Free |
| Rating | 4.2 (16 ratings) | 5.0 (2 ratings) — better |
| Positive reviews | 57.1% of reviews | 100.0% of reviews — better |
| Number of ratings | 16 — better | 2 |
| Update frequency | Every 10 days — better | Every 2 weeks |
| Ads | No | No |
| In-app purchases | Yes | No — better |
| Monetization | Free with in-app purchases | Free — better |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Requires iOS | 13.0 — better | 15.1 |
| Further details — not scored | ||
| Size | 540 MB | 36 MB |
| Age rating | 17+ | 17+ |
| Developer | American College of Physicians | International Guidelines Center, Inc |
Customer experience
ACP MKSAP
Guideline Central
In-app purchases
ACP MKSAP
- Non-member in-app price$999.991 Year
Guideline Central
No in-app purchases
Questions
Is ACP MKSAP free?
Is Guideline Central free?
Which has better reviews, ACP MKSAP or Guideline Central?
Do ACP MKSAP or Guideline Central have ads?
Which is updated more often, ACP MKSAP or Guideline Central?
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