Durham County SO NC vs GeneFox

The Durham County Sheriff's Office (NC) mobile application is an interactive app developed to help improve communication with area residents. The Durham County Sheriff's Office app allows residents to connect with the Durham County Sheriff's Office by reporting crimes, submitting tips, and other interactive features, as well as provides the community the latest public safety news and information. The app is another public outreach effort developed by the Durham County Sheriff's Office to improve communication with county residents and visitors. This app is not intended to be used to report emergency situations. Please call 911 in an emergency.

GeneFox explores public gene-expression and survival data from TCGA, NCBI GEO, GTEx, UCSC Xena, Treehouse, and CCLE. Statistics and visualizations run on your device; requests fetch only what your analysis needs. Built for scientists who work with gene-expression data — no coding required. WHAT YOU CAN DO • Browse 65 supported TCGA/NCI Genomic Data Commons cohorts with case counts, sites, disease types, and demographics. • Plot cohort gene expression as box, bar, or strip charts, stratified by clinical variables, subtype, sample type, or mutation status. • Split any of those plots by a second variable for a side-by-side descriptive comparison; reported statistics stay with the single-variable view. • Generate Kaplan–Meier curves with median summaries, log-rank p-values, and—where applicable—Cox High-vs-Low hazard ratios, 95% CIs, and proportional-hazards warnings. • Compare tumor vs. adjacent-normal and matched GTEx normal tissue via the UCSC Xena TOIL hub, with effect sizes and Mann–Whitney U statistics. • Explore 933 Treehouse CCLE v1 cell lines, grouped by TCGA acronym, tissue, disease, histology, or subtype. • Browse independent pediatric and rare-tumor cohorts from UCSC Treehouse, drawn from studies outside TCGA and TARGET. • Chart differential expression as an interactive volcano plot — expression or mutant-vs-wild-type contrasts — with panel-wise Benjamini–Hochberg FDR correction. • Render gene-panel heatmaps with hierarchical clustering, annotation strips, Z-normalization, and an outlier-resistant color scale. • Run Sample PCA (PC1/PC2) using up to 2,000 selected or top-variable genes, for GEO datasets and TCGA cohorts. • Score custom signatures or 41 curated presets from MSigDB, Reactome, and WikiPathways, plus the Wagle et al. 2018 MPAS panel. • Search NCBI GEO Series with cancer-term expansion. Supports series matrices, human NCBI-generated counts, complete-cohort ARCHS4 raw counts for GEO-classified human/mouse expression RNA-seq, and compatible supplementary matrices. • Capture charts in Report Builder and export a multi-figure report with an auto-generated methods section. ASK GENEFOX Ask questions in plain language. Local interpretation runs first; optional Cloud Assist sends only its disclosed interpretation payload after one-time or standing consent. Scientific analyses stay on-device. PRIVACY GeneFox has no ads, behavioral-usage analytics, or third-party tracking. No GeneFox account is required. Bookmarks stay private and are portable via export/import. DATA SOURCES Consult each provider's site for the authoritative source: • NCI Genomic Data Commons (TCGA and related programs): https://gdc.cancer.gov • NCBI Gene Expression Omnibus (GEO): https://www.ncbi.nlm.nih.gov/geo/ • ARCHS4 fallback terms and citation: https://archs4.org/help • GTEx Portal: https://gtexportal.org • UCSC Xena: https://xenabrowser.net • Treehouse Cell Line Compendium v1 (CCLE, July 2019): https://treehousegenomics.ucsc.edu/public-data-html/previous-compendia/ • Treehouse Tumor Compendium 25.01: https://treehousegenomics.ucsc.edu/public-data/ DISCLAIMER GeneFox is an independent, nonclinical app for scientific research. It is NOT a government app and is not affiliated with or endorsed by any government entity or agency (including the U.S. NIH, NCI, or NCBI) or any data provider above. GeneFox is not a medical device and does not diagnose, treat, cure, or prevent any medical condition. Consult a qualified healthcare professional for medical advice, diagnosis, or treatment. Its outputs are not validated for clinical decision-making. GeneFox is developed by Vindhya Data Science.