PathoPlay vs Cause & Cure

PathoPlay teaches pathophysiology and pharmacology by mechanism, not memorization. Trace how diseases start, how drugs treat them, and how the same molecular cascades recur across organ systems. Can you connect the chain? Portal hypertension → splanchnic capillary pressure → fluid transudation → ascites. Every link matters. Miss one, and the pathway breaks. Now treat it. Five drugs in your cart. Only one hits the right molecular target. Choose wrong, the cascade continues. Now sabotage it. A healthy cascade. Five insults: pathogens, toxins, autoantibodies, stressors. Only one disrupts the pathway at the right node. Drop it correctly, and watch the disease unfold step by step. FIVE MODES Chain — Drag and connect steps from trigger to clinical outcome. Reverse — Start with a clinical finding and trace backward to the root cause. How attendings think. Versus — Two similar diseases side by side. Fill in the gaps that distinguish them. Treat — Drag the correct drug onto the right molecular target to block the cascade. Pharmacology by mechanism. Sabotage — Drop the right pathogen, toxin, or autoantibody onto the node it disrupts. Watch the cascade fail in real time. PLUS Mechanisms — Study horizontally instead of by body system. 28 immunopathology, toxin, and hemodynamic clusters span every mode. Daily Challenge — One new chain every day. Build your streak in under 3 minutes. 650 PUZZLES ACROSS 10 BODY SYSTEMS Cardiovascular, Respiratory, Renal, GI & Hepatology, Neurology, Endocrine, Infectious Disease, Hematology, Reproductive, Rheumatology — pathophysiology, pharmacology, and mechanism-disruption in every system. Sabotage highlights: H. pylori, HBV cccDNA, C. difficile, doxorubicin cardiotoxicity, anti-PLA2R membranous, falciparum malaria, prion disease, MS, Hashimoto, Graves, TTP, HIT, APS, HPV cervical cancer, drug-induced lupus, statin myopathy. WHO IT'S FOR Medical students preparing for USMLE Step 1 and Step 2 CK. Nursing students mastering mechanisms for NCLEX. PA, NP, and pharmacy students building clinical reasoning foundations. Anyone who wants to understand why diseases happen and how drugs work. WHY IT WORKS Most study tools ask you to recall facts. PathoPlay asks you to think with mechanism as the unit of reasoning. Five different ways to engage the same molecular reality builds understanding that survives exam pressure and translates to clinical practice. Every puzzle ends with a clinical pearl referenced to standard medical textbooks. From the makers of MedDiagnosis (clinical case simulator) and Kinetics (USMLE biochemistry). ACCESS 200 chains free across all 10 body systems One-time purchase unlocks all four premium modes, the Mechanisms browse, and all future content, yours forever No subscriptions, no ads, fully offline Evidence-based content referenced to Robbins & Cotran, Harrison's, Guyton & Hall, Goodman & Gilman's, Pathoma, Nat Rev Dis Primers, NEJM, and Lancet. Support: contact@diagnosticstudios.com Educational use only. Not for clinical decision-making. USMLE® is a trademark of NBME/FSMB. No affiliation or endorsement.

Cause & Cure is a bidirectional clinical study reference. Start from a disease and see how it's treated. Start from a drug and see what it treats. Start from an organism and see what it causes and what covers it. Every link works in both directions, so you can follow your thinking instead of the app's. Built for the way rotations actually work: you hear a drug name on rounds and need to know what it's for, or you see a presentation and need to know what's likely and what to reach for. WHAT'S INSIDE • Diseases with specialty, management overview, and tagged treatment options • Medications with class, mechanism, indications, dosing, half-life, metabolism, excretion, monitoring, max dose, renal/hepatic adjustment, and pregnancy/lactation notes • Organisms with type, morphology, features, and source — plus how each presents as a syndrome, and which drugs cover it • A drug interaction reference, organised by severity THERAPY TAGS Treatments are tagged first-line, alternative, second-line, prophylaxis, adjunct, symptomatic, or avoid — with a "use when" note explaining the context. Rename and recolour the tags to match how you think. HOSPITAL-SPECIFIC PLANS Formularies differ between sites. Tag a treatment to a hospital and it appears alongside the general standard, so you can carry one reference across rotations without losing what's specific to where you are. DAILY QUIZ Ten questions a day, generated from the reference itself — first-line therapy, what a drug treats, which organism causes a syndrome, coverage, mechanisms, half-lives. Miss one and it comes back tomorrow; get it right and it spaces out. Nearly 1,800 questions. MARK WHAT YOU TRUST Flag an entry as verified, or as needing correction with a note on what's wrong. Your review status is personal to you, and a data update will never overwrite something you've verified. SEARCH One search field covers diseases, medications, and organisms at once. PRIVATE AND OFFLINE No account. No analytics. No tracking. No servers. Everything you add stays on your device. The full reference ships inside the app and works with no connection. IMPORTANT — PLEASE READ Cause & Cure is a study and reference tool for medical education. It is not medical advice and not a substitute for professional clinical judgement. It must not be used to diagnose, treat, or make decisions for real patients. Drug doses and treatment information are study drafts curated from third-party references and may be incomplete, out of date, or incorrect. Always verify against an authoritative source and current guidelines before any clinical use. The interaction reference is a study aid only — not a real-world interaction checker. It shows only what is in its own catalogue, and an empty result never means a combination is safe. Do not enter patient-identifiable information into the app.