RO Toolbox vs OneRx

The RadOnc Toolbox is a resource for health care professionals that is designed to support evidence-based practice. This point-of-care tool compiles frequently accessed references related to the delivery of radiation therapy, including dose constraints, calculators, clinical practice guidelines, staging, and other oncology resources.    The RadOnc Toolbox was created by Malolan Rajagopalan, MD, MBA, who was Principal Investigator of a grant from the ASTRO Foundation, then known as the Radiation Oncology Institute (ROI), that aimed to develop a resource to manage acute and late radiation toxicity. The Foundation assumed responsibility for the RadOnc Toolbox and released the first version in 2016. Since then, the Foundation has continued to add resources and enhance the content.   The redesigned RadOnc Toolbox released by the Foundation in 2023 is produced in collaboration with Red Canvas, LLC.

OneRx — Your Evidence AI for Clinical Decision Support

 OneRx is an AI-powered medical evidence assistant designed to help clinicians access fast, reliable, and reference-backed information at the point of care. It brings together peer-reviewed research, standard guidelines, and structured clinical reasoning to support better-informed decisions.

 With OneRx, clinicians can: 
• Ask clinical questions and receive structured, evidence-based summaries
 • Access research findings from trusted, publicly available sources
 • Review treatment options, toxicity profiles, contraindications, and monitoring needs
 • Get simplified comparisons of therapies and relevant clinical considerations
 • Use clear citations and transparent reference lists
• Improve the speed and confidence of everyday clinical decision-making

 OneRx is built to assist—not replace—professional medical judgment. It is designed for doctors, researchers, and medical teams who need quick access to high-quality information while staying aligned with evidence-based care.