HeartFlow vs AngioAID 3D

The HeartFlow® mobile app is a convenient way for clinician customers to see the status of their patients’ HeartFlow FFRct Analyses. Quickly scan a list of patients in your institution with the HeartFlow Analysis and view patients’ personalized 3D models with FFRct values. If you are not currently a HeartFlow customer but are curious to try the HeartFlow Analysis, you can still preview the 3D model in a quick introduction experience. Note: Important differences exist in how FFRct values are presented in the mobile app. Please contact HeartFlow Support (support@heartflow.com) with any questions. http://www.heartflow.com **** About HeartFlow: HeartFlow is transforming the way cardiovascular disease is diagnosed and treated. Our HeartFlow FFRct Analysis is a non-invasive cardiac test that creates a personalized 3D model of the heart. Clinicians use this analysis to evaluate blood flow to the heart and to help them determine the appropriate treatment pathway for each patient with suspected coronary artery disease (CAD). Why the HeartFlow Analysis matters: • Regulated medical device with FDA 510(k) clearance, CE mark and PMDA approval. • Substantial clinical evidence with more than 500 peer-reviewed articles • Centers for Medicare and Medicaid Services (CMS) approved reimbursement in the US • Recommended by NICE and mandated by NHS England and NHS Improvement through the MedTech Funding Mandate • Over 235 million patients in the US have access to the HeartFlow Analysis through their current health insurance • Improves clinical outcomes through earlier detection of CAD without intervention or adverse events - 83% reduction in unnecessary angiograms* • Helps reduce the overall cost of care - 26% reduction based on the mean one-year per-patient cost* • Leverages deep learning for product improvements in accuracy and turnaround time • Improves the overall patient experience and quality of life* - hear from a few of the more than 100,000 patients touched by HeartFlow on our web site The HeartFlow FFRct Analysis is commercially available in the United States, Canada, Europe, and Japan. The HeartFlow Mobile Application is only commercially available in the United States, Canada, and the UK. Don’t have HeartFlow at your institution? Submit a request, and we’ll help get the conversation started. http://www.heartflow.com/contact-us * Douglas, et al. J Am Coll Cardiol 2016; 68:435-45.

AngioAID 3D is educational tool designed to teach key concepts of diagnostic angiography of coronary arteries. Developed at the Mount Sinai Hospital in New York City, New York State's highest volume cardiac cath lab, we aim to provide an interactive learning experience on this important topic. Within a 3D live simulation, you begin by advancing a diagnostic guidewire into the aortic root. Then, advance one of many diagnostic catheter options to either the right of left coronary ostium. Through pushing and pulling, as well as rotation of the catheter, try to achieve a truly co-axial engagement of the coronary ostium with the catheter. Meanwhile monitor the hemodynamic tab which simulated damping from over-engagement or roofing of the catheter tip. Line up the view with the target view, zoom to fill the screen with he coronaries, and rotate the C-Arm LAO/RAO and Cranial/Caudal until you're where you think you need to be. Finally, inject dye and take a cine to compare with the one we actually did in the cath lab for this set of coronaries. In addition to the diagnostic simulation, "Review Mode" allows you to play with angles and panning while always being able to see the vessels with no dye injection needed. Also a collection of key topics have been included within the review mode such as key angiographic angles depending on what you're aiming to see clearly, vessel segmentation conventions, and more coronary anatomy and angiography pearls. We highly recommend you view the tutorial video that is available when you first open the application or from the settings page to understand all of the available functions. The first launch has a normal set of coronary arteries but please stay tuned while we create more sets of coronaries such as anomalous coronaries and bypass grafts.