Best Drug Apps & Games

250+ iOS apps & games curated and reviewed

4.5 avg rating

20 free apps & games

Updated November 2026

The best drug apps and games on iPhone average 4.5★ across 250+ titles — we've ranked them by what real users actually keep on their phones. Updated November 2026.

Compare top Drug Apps & Games (November 2026)

#	App	Price	Rating	Ads	In-App Purchases	Updated
1	Plug: Build your Empire IRL	Free	4.7★ (2K)	No	Yes	Nov 2026
2	Substance Syndicate Tycoon V	Free	4.6★ (37K)	Yes	Yes	Nov 2026
3	Grand Drug Dealer: Simulator	Free	4.6★ (1K)	Yes	Yes	Nov 2026
4	Urban Drug Empire	Free	4.6★ (31K)	No	Yes	Nov 2026
5	Drugs.com Medication Guide	Free	4.8★ (18K)	Yes	No	Nov 2026
6	Weed Inc: Idle Tycoon	Free	4.8★ (237K)	Yes	Yes	Nov 2026
7	WiseDrug دەرمانی زیرەک	Free	4.3★ (197)	No	Yes	Oct 2026
8	KnowDrugs Drug Checking	Free	4.7★ (38)	No	Yes	Oct 2026

Top Picks for Drug

#1

Plug: Build your Empire IRL by Nocturne Games

Mafia Crime Tycoon on Real Map

Editor's Choice

4.7(2K ratings)

FreeIn-App Purchases

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Build a criminal empire on a real-world map. Manage supply chains, deal on actual streets, and launder money. Recruit a cartel and rise from a corner hustler to a kingpin.

#2

Substance Syndicate Tycoon V by Jithin K Satheesh

Build your empire

Strong Contender

4.6😊(37K ratings)

FreeAdsIn-App Purchases

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Start from the bottom and build a criminal empire. Grow and sell your own product, manage operations with hired help, and expand your influence. Be wary of law enforcement and make strategic decisions to survive and thrive in this high-stakes simulation.

What We Love

👍 Good game
👍 Very good potential
👍 Interesting at the beginning

Room to Improve

🐛 Bugs
🐛 Buggy
🐛 Objective 19 and 22 bugged

#3

Grand Drug Dealer: Simulator by NewGen Studio LLC

Empire Tycoon: City Simulator

Worth Considering

4.6(1K ratings)

FreeAdsIn-App Purchases

#86in Games

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Build and manage your own urban empire by making strategic decisions. Expand your territory, serve customers, and upgrade your operations to achieve virtual success. This simulation game offers idle progression and real-time strategy elements.

More Drug apps to explore

Urban Drug Empire

Urban Drug Empire

Urban Drug Empire

Become a kingpin in this strategy and life simulation game. Expand your drug trade empire, manage supply and demand, and outmaneuver rivals and law enforcement. Your strategic choices will pave the way to power and luxury.

Strategy and life simulationBuild a drug trade empireManage supply and demand

free with in-app purchases

Drugs.com Medication Guide

Drugs.com Medication Guide

Drugs.com Medication Guide

Know more. Be sure.

Access comprehensive information on over 24,000 medications, including prescription drugs, OTCs, and natural products. Manage your medications, check for interactions, identify pills, and find the lowest prices. Stay informed with FDA alerts and detailed side effect information.

Medication list with interaction trackingDrug price comparison and pharmacy finderPill identification by imprint, color, and shape

free with in-app purchases

Weed Inc: Idle Tycoon

Weed Inc: Idle Tycoon

Weed Inc: Idle Tycoon

Grow your money empire!

Build and automate a cannabis business empire in this addictive idle tycoon simulation. Grow your operation, hire managers, and expand to new locations to earn offline profits and dominate the industry.

Build and grow a weed empireAutomate business for idle offline earningsUnlock powerful upgrades

free with in-app purchases

WiseDrug دەرمانی زیرەک

WiseDrug دەرمانی زیرەک

WiseDrug دەرمانی زیرەک

Wise Drug : الدواء ذكي

This medical app provides comprehensive information on medications and their usage. Users can identify drugs by taking a photo or search for them by disease name. It also offers insights into laboratory tests and vitamins.

Identify drugs by photoSearch drugs by diseaseView lab test information

free with in-app purchases

KnowDrugs Drug Checking

KnowDrugs Drug Checking

KnowDrugs Drug Checking

Pill reports & Harm reduction

Access drug testing results, pill warnings, and drug alerts. Provides information on over 200 substances, harm reduction advice, and strategies for safer use. Helps users make informed decisions to minimize potential risks.

Drug testing results lookupPill warnings and alertsInformation on 200+ drugs

💪 Health & Fitness

free with in-app purchases

Drug Dealer Sim Syndicate

Drug Dealer Sim Syndicate

Drug Dealer Sim Syndicate

by MOMIN K BUTT

Build your criminal empire from the ground up in this intense simulation game. Produce and deal illegal substances, manage your crew, and avoid law enforcement and rival gangs to become the most feared name in the city.

Produce and deal illegal substancesManage a criminal syndicate and crewUpgrade safehouses and establish labs

free with in-app purchases

Weed Firm 2: Back To College

Weed Firm 2: Back To College

Weed Firm 2: Back To College

Top 420 drug dealer simulation

Cultivate and sell various strains of marijuana in this simulation game. Meet eccentric clients, defend your stash from law enforcement, and expand your business to space. Features minigames and crypto mining for exclusive content.

Cultivate multiple marijuana strainsSell to eccentric clienteleCustomize your shop

free with in-app purchases

Drugs Dealer Gang Wars

Drugs Dealer Gang Wars

Drugs Dealer Gang Wars

Grand Mafia & Gang Beasts 3D

Explore a vast open world in New Orleans, engaging in thrilling story missions, intense car chases, and explosive shooting action. Build your criminal empire by taking over territories, expanding your properties, and managing your illicit business.

Vast open world explorationEngaging story missionsIntense car chases and shooting

free with in-app purchases

Bud Farm: Grass Roots

Bud Farm: Grass Roots

Bud Farm: Grass Roots

Top Weed Game and Simulation

Cultivate your own marijuana farm, from planting to harvesting. Upgrade your facilities, decorate your space, and manage your business by producing goods and hiring staff. Compete in contests and trade with friends in this engaging simulation game.

Plant, grow, water, trim, and harvest marijuanaUpgrade buildings and decorate your farmProduce goods and hire workers

free with in-app purchases

by Crary Drugs Inc

Manage your family's prescriptions and access important medication information, including uses and side effects. Request refills quickly and explore a drug library with health articles and videos. Find store directions and hours.

Family prescription managementMedication information (uses, side effects)Quick refill requests

Drugs Empire: Mafia Tycoon

Drugs Empire: Mafia Tycoon

Drugs Empire: Mafia Tycoon

Build Your Cartel Empire

Escape prison and rebuild a powerful crime syndicate. Recruit loyal members, expand illicit businesses, and wage wars against rivals. Idle mechanics ensure continuous income as you grow your empire from a small operation to a vast narco dominion.

Build a crime empireRecruit gangsters and dealersManage illicit businesses

free with in-app purchases

Narcos: Cartel Wars & Strategy

Narcos: Cartel Wars & Strategy

Narcos: Cartel Wars & Strategy

Building mafia gang empire

Step into the role of a cartel kingpin in this official game of the hit TV show. Build your empire, recruit sicarios, wage war against other players, and manage your operations to maximize profit. Form alliances and dominate the drug trade.

Build and manage a cartel empireRecruit and level up sicariosWage war against other players

free with in-app purchases

PICU Drug Dosing Guide

PICU Drug Dosing Guide

PICU Drug Dosing Guide

by BJC Healthcare

This app provides drug dosing information, warnings, contraindications, and notes for commonly used medications within a specific pediatric intensive care unit. Users can browse guides by category or search for specific drugs to access detailed information. It also facilitates feedback and connection with intensivists for transfers and consultations.

Drug dosing informationWarnings and contraindicationsNotes on commonly used drugs

Drug Glossary: Gulf Edition

Drug Glossary: Gulf Edition

Drug Glossary: Gulf Edition

UAE, KSA, Egypt, Qatar, Bahran

Access a comprehensive offline database of over 30,000 registered human drugs and their pricing. Search by generic or trade name for detailed information including dosage form and strength. Essential for healthcare professionals in Egypt and the Gulf region.

Offline drug database30,000+ drug listingsSearch by generic/trade name

Manage your prescriptions

Medicards drug card app

Medicards drug card app

Medicards drug card app

A drug card study app

Master medication knowledge and critical thinking with scope-specific drug cards and quizzes. Tailored content for EMTs, Paramedics, and RNs helps reduce test anxiety and improve real-world decision-making. Track progress and study offline.

Scope-specific drug cardsFiltered study by categoryRandom and filtered quizzes

free with in-app purchases

Bloomington Drug

Bloomington Drug

Bloomington Drug

by Bloomington Drug

Manage your family's prescriptions and view medication details like uses and side effects. Request refills quickly and access a drug library for more information. Stay informed with health articles and videos, and find store directions and hours.

Family prescription managementMedication details (uses, side effects)Quick refill requests

FAQ about Drug

What are the best drug apps & games for iPhone?

Plug: Build your Empire IRL tops our drug apps & games ranking as of November 2026, with a 4.7-star average from 2K App Store ratings, and it's free to download.

Are there free drug apps & games for iPhone?

Yes — 20 of the top drug apps & games we rank are free to download, including Plug: Build your Empire IRL and Substance Syndicate Tycoon V.

Does Plug: Build your Empire IRL have ads or in-app purchases?

Plug: Build your Empire IRL has no ads and offers in-app purchases, according to its App Store listing as of November 2026.

How many drug apps & games are on the App Store?

We track 250+ drug apps & games on the iOS App Store as of November 2026, ranked by rating, recency, and analysis of real user reviews.

Related searches

drugs.com drug dealer simulator drug dealer games drugs.com medication guide drug interaction checker drug wars drug empire drug guide drug game