Best games like Dermis Defense

10+ similar games compared and reviewed

4.4 avg rating
10 free games
Updated August 2026

Dermis Defense is great, but it's not the only option. Explore 10+ similar apps and games for iPhone and iPad, each reviewed and rated by real users. Find free alternatives, premium upgrades, and hidden gems.

Top Alternatives to Dermis Defense

Cellmaniac: Virus Defense#1

Cellmaniac: Virus Defense by Norbert Fritz

Fight germs. Evolve cells.
Editor's Choice
🎮 Games
3.8(4 ratings)
FreeAdsIn-App Purchases
Cellmaniac: Virus Defense screenshot 1
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Cellmaniac: Virus Defense screenshot 3
Cellmaniac: Virus Defense screenshot 4

Engage in a thrilling biology-inspired adventure where you defend against invading germs. Upgrade your defenses, evolve your immune system, and learn about how the body fights infection through fun, physics-based gameplay.

Virus Evolution: Destroy Earth#2

Virus Evolution: Destroy Earth by Kwalee Ltd

Spread the Bacteria Infection!
Strong Contender
🎮 Games
4.6😞(848 ratings)
FreeAdsIn-App Purchases
Virus Evolution: Destroy Earth screenshot 1
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Virus Evolution: Destroy Earth screenshot 3
Virus Evolution: Destroy Earth screenshot 4
Virus Evolution: Destroy Earth screenshot 5

Unleash a deadly pathogen and strategically spread a global pandemic. Your goal is to conquer humanity by increasing infection rates and decreasing survival rates. Become the ultimate threat and achieve world domination.

What We Love

  • ❤️ Love the game
  • 🎉 Enjoyable to play

Room to Improve

  • 🐛 Game freezes/crashes
  • 🚫 Broken/glitched features
  • 🔍 Limited geographical coverage
Bacterias#3

Bacterias by Yso Corp

Worth Considering
🎮 Games
3.8(194 ratings)
FreeAds
Bacterias screenshot 1
Bacterias screenshot 2
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Create unique monsters by injecting bacteria into creatures. Discover new species and expand your collection of bizarre beings. A simple yet engaging game for those who enjoy creature creation and collection.

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4
Idle evolution: Life on Earth
Idle evolution: Life on Earth
Idle evolution: Life on Earth
Start evolution. Meet dinosaur
Free

Explore the 4-billion-year history of life on Earth through an engaging idle game. Learn about ancient creatures and human culture while restoring biological forms and unlocking evolutionary mysteries. Experience a blend of casual gameplay and educational content.

Casual idle gameplayPopular science educationBiological restoration
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5
Earth Editor
Earth Editor
Earth Editor
Sandbox game
Free

Create your own world by placing various elements like sand, water, and lava on a gravity field. This simulation game allows for boundless creativity in designing unique planetary landscapes. Explore the possibilities of a sandbox environment where you are the architect of your own planet.

World creation sandboxGravity field simulationPlace sand, water, seeds, lava
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Rise of Virus
Rise of Virus
Rise of Virus
by 英 李
Free
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Pill Fortress
Pill Fortress
Pill Fortress
by Voodoo
Free

Defend your fortress against waves of viruses in this immune-themed base defense game. Strategically place and upgrade unique pill defenders to overcome evolving viral threats. Enjoy kid-friendly gameplay with vibrant 2D graphics.

Dynamic pill placementEvolving viral threatsUnlock new pill characters
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8
Slime Weapon Master
Slime Weapon Master
Slime Weapon Master
by Solid Games
Free

Build and sell weapons in your own factory. Upgrade your production lines to forge higher-grade weapons faster and earn more gold. Expand your operations to maximize profits and fill your treasure chests.

Build weaponsSell weaponsUpgrade production lines
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9
Bead Toy ASMR
Bead Toy ASMR
Bead Toy ASMR
ASMR with colorful beads!
Free

Engage in a unique sensory experience by manipulating colorful beads. Watch them flow through gears and multiply as you expand your play area. This app offers a visually satisfying and calming ASMR journey.

Colorful bead manipulationGear mechanics interactionBead multiplication
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10
Click to Life
Click to Life
Click to Life
by SUPERSONIC STUDIOS LTD
Free

A challenging puzzle game where you must strategically pump blood and connect veins to ensure vital organs receive circulation. Restore life by successfully navigating the circulatory system.

Pump bloodConnect veinsRestore organ circulation
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