TherapySelector vs OpenEvidence

TherapySelector supports you as a physician to easily and quickly choose a data-based, person-centered treatment for hypertension and hepatitis C for and with your patient during consultation hours. The app shows in a single glance information about the effectiveness of medication based on the disease remission (systolic blood pressure lower than 140 mmHg for hypertension and viral clearance in hepatitis C), the likelihood of adverse events, cost and patient group size. This overview allows you to easily and quickly decide on the best person-centered treatment method for your patient, based on study data. How does TherapySelector work? First you enter the requested characteristics of your patient by answering 4 simple questions about etiology, disease stage, previous treatments and comorbidities. Based on this, a profile of the patient is determined. The app then shows an overview of all registered treatments for that specific patient profile, based on frequently updated study results. For each therapy you find information about effectiveness, possible adverse events and costs. TherapySelector currently provides the following features: • Determination of patient profiles based on four simple questions about the patient. • Probability of "success" of all registered medication (combinations) for hypertension and hepatitis C, together with the probability of adverse events associated with the patient profile, based on individual patient data from key clinical scientific studies. • For hypertension: overview of therapy options with Thiazide diuretics (THZ), Calcium Channel Blockers (CCA), ACE inhibitors (ACEi) or Angiotensin Receptor Blockers (ARB). Information on monotherapy with dose increase (Titrate), and results of stepwise addition of medication (Titrate & Add). • Detail information, including information about dosage (of the therapy regime) and the cost of a specific treatment. • Availability in both English and Dutch. TherapySelector is intended to provide physicians and patients person-centered information to support them in choosing the most appropriate treatment. In doing so, the app complements guidelines that are based on the ‘average’ patient. The TherapySelector app can be used without creating an account. Developed with (academic) medical centers and research institutes TherapySelector is developed by TherapySelector in collaboration with physicians and scientists associated with universities and leading academic medical centers such as the Erasmus MC, LUMC and MUMC+. The data in the app has been authorized by specialists from Dutch scientific associations. The results are calculated using anonymous patient data from scientific studies of published randomized controlled trials, other phase 2 & 3 studies and prospective real-life studies around the world (high quality research). Research groups and sponsors make their data available for this purpose. About TherapySelector TherapySelector B.V. is a social enterprise. Our mission is to improve health care globally by enriching it with person-centered treatment information based on the most recent data from scientific studies. It is not our goal to make profit. With the TherapySelector app, we facilitate doctors with person-centered care to achieve health gains for their patients. Additionally, we want to aid in controlling the rising costs of healthcare for the public, e.g. by preventing over- and under-treatment. Follow us on LinkedIn (https://www.linkedin.com/company/therapyselector) or visit www.therapyselector.com.

Clinical Decision Support & Medical Search Engine for Healthcare Professionals (NPI Required) OpenEvidence is the most widely used clinical decision support platform and medical search engine among U.S. clinicians. According to independent studies, more American physicians use OpenEvidence than all other AI platforms combined. OpenEvidence is trusted by millions of verified healthcare professionals to make high-stakes clinical decisions at the point of care with answers that are sourced, cited, and grounded in peer-reviewed medical literature. Founded with the mission to organize and expand the world's collective medical knowledge, OpenEvidence is actively used daily by the majority of physicians in the United States. OpenEvidence is free for all verified U.S. clinicians. AN OFFICIAL AI PARTNER OF: The New England Journal of Medicine (NEJM) The Journal of the American Medical Association (JAMA) and its 11 specialty journals National Comprehensive Cancer Network (NCCN) Nature Cochrane Library Wiley WHAT YOU GET: • Specific answers to clinical questions, with every claim cited to its source • 35 million+ peer-reviewed papers, 300+ medical journals, plus FDA and CDC sources • Licensed full text from NEJM, JAMA, Nature, Cochrane, and others • EvidenceGrade™: see the strength of the evidence behind every answer • CME and MOC credits, earned by asking questions • Visits for ambient documentation, Dialer for secure patient calls, and Voice Mode for hands-free answers CONTENT AGREEMENTS AND COLLABORATIONS: American Academy of Family Physicians (AAFP) American College of Cardiology (ACC) American Diabetes Association (ADA) American Academy of Pediatrics (AAP) American College of Obstetricians and Gynecologists (ACOG) American College of Emergency Physicians (ACEP) ASCO Guidelines American Academy of Orthopaedic Surgeons (AAOS) American Academy of Ophthalmology (AAO) American Urological Association (AUA) Plus AAO-HNS, GINA, SNO, SSO, and more. IN USE ACROSS: 10,000+ hospitals and medical centers nationwide, including Mayo Clinic, Mount Sinai, Cedars-Sinai, MSKCC, and Sutter Health. WHY CLINICIANS TRUST US: • HIPAA compliant across the platform • NEJM, JAMA, Nature, and NCCN—official content partners 
 • Tens of millions of clinical consultations per month WHAT CLINICIANS SAY: “OpenEvidence is currently the best AI tool for medical information.” — Dr. Paul Sax, Infectious Disease, Brigham and Women’s Hospital, Review in The New England Journal of Medicine Journal Watch (now NEJM Clinician) “In a morning report, a resident had a question that I didn’t know the answer to, but we were able to open OpenEvidence and get an answer on the spot.” — Dr. Kyle P. Lehenbauer, Minneapolis Veterans Affairs Medical Center “I use OpenEvidence multiple times during the day and every day. I am a better doc because of this. I expand my differential diagnoses and verify the science behind choices of treatments.” — Dr. Sharon E. Martin, Southern Huntingdon Medical Center Important note: OpenEvidence is available only to healthcare professionals. Users must verify their healthcare professional status before using OpenEvidence.