ASTCT Practice Guidelines vs EBMT Educational Tools

ASTCT practice guidelines and clinical calculators for blood and bone marrow transplantation, and cellular therapies. The ASTCT Practice Guidelines application provides up to date access to practice guidelines, evidence-based reviews and position statements from the ASTCT Committee on Practice Guidelines. These documents are developed and updated by leading experts in the field of blood and bone marrow transplantation and cellular therapy. In addition the app includes clinical calculators relevant to HCT patients. These tools will allow immediate access to information that can help guide clinical decision making. Topics covered include: • General guidelines • Conditioning regimens • Stem cell collection and mobilization • Graft-Versus-Host disease • HCT for Malignant and non-Malignant Hematologic Diseases, including pediatric and adult patients • Supportive Care • Survivorship Detailed references and full access to source papers is also provided. The American Society for Transplantation and Cellular Therapy (ASTCT) is an international professional membership association of physicians, investigators and other health care professionals, dedicated to improving the application and success of blood and marrow transplantation and related cellular therapies.

The new 2018 EBMT Educational Tools application provides a SOS/VOD Severity Grading calculator based on the 2016 Revised diagnosis and severity criteria for SOS/VOD (Bone Marrow Transplant. 2016 Jul; 51(7): 906–912., M. Mohty et. all). Abstract: Sinusoidal obstruction syndrome, also known as veno-occlusive disease (SOS/VOD), is a potentially life threatening complication that can develop after hematopoietic cell transplantation. Although SOS/VOD progressively resolves within a few weeks in most patients, the most severe forms result in multi-organ dysfunction and are associated with a high mortality rate (>80%). Therefore, careful attention must be paid to allow an early detection of SOS/VOD and severity assessment. The aim of this educational application is to help investigators in the diagnosis, and a severity-grading system for SOS/VOD in adult patients, on behalf of the European Society for Blood and Marrow Transplantation. The European Society for Blood and Marrow Transplantation (EBMT) is a non-profit organisation that was established in 1974 in order to allow scientists and physicians involved in clinical bone marrow transplantation to share their experience and develop co-operative studies. The EBMT is devoted to the promotion of all aspects associated with the transplantation of haematopoietic stem cells from all donor sources and donor types including basic and clinical research, education, standardisation, quality control, and accreditation for transplant procedures. Development of this EBMT Educational Tool was made possible thanks to an unrestricted educational grant from Jazz Pharmaceuticals.