Comparison

neoDefense vs STEM Defense

Price, ratings, monetisation and update history for both games, side by side — with what reviewers say about each.

Head to head
About

neoDefense

Defend a sprout of new life from invading creeps by building and upgrading your fortress. Strategize with various weapons to overcome challenging missions and defeat powerful bosses. Enjoy mind-boggling graphics and thrilling sound effects in this unique tower defense experience.

Highlights
  • Build and upgrade fortress
  • Over 2,500 enemy waves
  • 99 challenging missions
  • 5 upgradable weapons
  • Boss battles
  • Stunning vector graphics
  • Thrilling sound effects
Features
Read full description

DEFEND YOUR SPROUT OF NEW LIFE FROM INVADER! [Build, Upgrade and Sweep!] neoDefense is a defense game set in a core of new life invaded by countless creeps. A game that is a new twist of tower defense games, something that will keep you hooked and intriguingly challenged! YOU ARE UNDER ATTACK Build your fortress any way you wish, upgrade weapons and let the invasions begin! And sweep them! Don’t go over yourself & think that you can always win – strategize! MAKE SMART DECISIONS This game need your brilliant idea to defeat enemies attack! Each mission has its own mind-challenging hardness, show that your enemies can never outsmart you. Use weapons, plan and destroy the invaders. MIND-BOGGLING GRAPHICS & SOUNDS Enjoy stunning vector graphics accompanied with thrilling sound effects & animations. Be prepared for astounding visual heaven. One of the best you’ll see in a defense game. [neoDefense FEATURES] • Build your own fortress for incoming waves of enemies! • More than 2,500 waves of creeps across 99 missions (And will be added more later!) • 5 upgradable weapons to kill the creeps with style (And will be added more later!) • There is a BOSS at the end of each group of missions (It's too hard to beat!) • Amazing soundtrack in each group of missions • Astounding variation of the classic defense games [IN-APP PURCHASES] Each in-app purchase can make you challenge more missions from Gamma sector. [SUPPORT AND FEEDBACK] Please contact duetblock@duetblock.com with any inquiry or feedback. Please visit http://www.duetBlock.com for more detail.

About

STEM Defense

Features
Read full description

About This Game "STEM Defense" immerses yourself in a strategic battle within the human body, where you manipulate pathways and tower placements on a dynamic hexagonal grid. This educational tower defense game teaches players about the immune system through engaging gameplay, focusing on the defense against microscopic invaders. Key Features Path Expansion: Dynamically extend the pathways pathogens travel to strategically shape each level and increase the effectiveness of your defenses. Tower Placement Strategy: Strategic placement of your towers is essential. Elevate your towers to gain damage bonuses, crucial for optimizing defense effectiveness. Mutation-Based Upgrades: Enhance your defenses through epigenetic modifications, providing temporary boosts, and genetic mutations for permanent enhancements. This mirrors real-life biological defense mechanisms. Experience and Genetic Enhancements: Gain experience to unlock advanced defensive capabilities and permanent genetic upgrades, enhancing your ability to combat pathogens. Varied Enemy Types: Encounter diverse pathogens, each with unique abilities. Develop strategies to handle enemies that can regenerate, accelerate, or spawn additional threats. Endless Replayability: With a multitude of genetic enhancements and adaptive enemy tactics, each game offers new challenges and decisions, ensuring unique experiences with every playthrough. Coming Soon:Acquired immunity mechanics!! Support Independent Development As a solo developer not well-versed in the art of social media, I rely on the support of players like you. If you've enjoyed "STEM Defense," please help spread the word and make it known to others!

Screenshots

neoDefense4 screens
STEM Defense4 screens

Verdict

The call

The clearest difference is in-app purchases: STEM Defense at none against neoDefense's 5. STEM Defense also leads on update cadence (every 3 days vs every 2 months) and device support (4 vs 2). neoDefense's advantage is price ($1.99 vs $6.99) and iOS requirement (9.0 vs 15.0). On ads there is nothing between them.

Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS

CostPrice · In-app purchases · Ads · Monetization

neoDefense costs $1.99 and STEM Defense $6.99 up front. neoDefense sells 5 one-off in-app purchases. STEM Defense asks for nothing beyond the download.

UpkeepUpdate frequency

neoDefense ships an update every 2 months, STEM Defense every 3 days. The most recent releases landed on October 26, 2026 and August 22, 2026 respectively.

Scorecard5 real differences · 5 level
neoDefense versus STEM Defense: the parameters behind the verdict, then further details
ParameterneoDefenseSTEM Defense
Price$1.99 — better$6.99
Rating4.7 (547 ratings) — better—
Positive reviews87.7% of reviews—
Number of ratings547 — better—
Update frequencyEvery 2 monthsEvery 3 days — better
AdsNoNo
In-app purchasesYesNo — better
MonetizationFree with in-app purchases—
DevicesiPhone, iPodiPhone, iPad, iPod, Mac — better
Requires iOS9.0 — better15.0
Further details — not scored
Size156 MB411 MB
Age rating9+9+
DeveloperSON GILAndrea Carlomaria Sertorio

Bugs and requests

neoDefense

Reported bugs

3 issues
  • Impossible to complete certain levels
  • Compatibility issues on some devices
  • Boost tower not available as advertised

Requested features

5 requests
  • More levels and content updates
  • Option to reset levels
  • Ability to save progress across devices
  • Difficulty settings or modes
  • More tower/weapon variety

STEM Defense

Not enough reviews yet to summarise bugs or requests.

In-app purchases

5 purchases

neoDefense

One-time5
  • Unlock & Play Gamma Sector$0.99
  • Unlock & Play Delta Sector$0.99
  • Unlock & Play Epsilon Sector$0.99
Show 2 more
  • Unlock & Play Zeta Sector$0.99
  • Unlock & Play Eta Sector$0.99
None

STEM Defense

No in-app purchases

Questions

Is neoDefense free?
neoDefense costs $1.99, and also offers in-app purchases.
Is STEM Defense free?
STEM Defense costs $6.99, with no in-app purchases.
Do neoDefense or STEM Defense have ads?
Neither neoDefense nor STEM Defense shows ads.
Which is updated more often, neoDefense or STEM Defense?
neoDefense ships an update every 2 months, and STEM Defense every 3 days. Most recently, neoDefense was updated on October 26, 2026 and STEM Defense on August 22, 2026.

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