EBMT Educational Tools vs RBCX Calculation Tool

The new 2018 EBMT Educational Tools application provides a SOS/VOD Severity Grading calculator based on the 2016 Revised diagnosis and severity criteria for SOS/VOD (Bone Marrow Transplant. 2016 Jul; 51(7): 906–912., M. Mohty et. all). Abstract: Sinusoidal obstruction syndrome, also known as veno-occlusive disease (SOS/VOD), is a potentially life threatening complication that can develop after hematopoietic cell transplantation. Although SOS/VOD progressively resolves within a few weeks in most patients, the most severe forms result in multi-organ dysfunction and are associated with a high mortality rate (>80%). Therefore, careful attention must be paid to allow an early detection of SOS/VOD and severity assessment. The aim of this educational application is to help investigators in the diagnosis, and a severity-grading system for SOS/VOD in adult patients, on behalf of the European Society for Blood and Marrow Transplantation. The European Society for Blood and Marrow Transplantation (EBMT) is a non-profit organisation that was established in 1974 in order to allow scientists and physicians involved in clinical bone marrow transplantation to share their experience and develop co-operative studies. The EBMT is devoted to the promotion of all aspects associated with the transplantation of haematopoietic stem cells from all donor sources and donor types including basic and clinical research, education, standardisation, quality control, and accreditation for transplant procedures. Development of this EBMT Educational Tool was made possible thanks to an unrestricted educational grant from Jazz Pharmaceuticals.

The Spectra Optia® Apheresis System RBCX Calculation Tool is intended to help medical professionals who are responsible for prescribing and performing red blood cell exchange (RBCX) procedures to estimate the volume of replacement fluid required to perform a procedure on the Spectra Optia system. Using the same patient data and the same fluid data that is entered on the Spectra Optia system, the RBCX Calculation Tool calculates and displays the estimated volume of replacement fluid required to achieve the target Hct and FCR. It can also determine whether a custom prime is recommended. While the tool is intended to help prepare for a procedure, it is not intended to be used for making medical decisions. Use of the Spectra Optia® Apheresis System RBCX Calculation Tool on iOS requires iOS version 14.0 or above. For more information about the tool, see the About page.