PediQUEST vs Nerbio iTOF

• The Pediatric Quality of Life and Evaluation of Symptoms Technology (PediQUEST) is designed to help health care providers learn more about your quality of life. • As of now, the App is only used within specific research studies. In order to use it, you need to be enrolled in one of our PediQUEST research studies and be registered by our research staff into the PediQUEST system. • Initially designed for children, adolescents and young adults with cancer, and their parents, the PediQUEST app regularly asks patients and parents, how the child, teen or young adult is feeling. Sometimes, depending on the study, patients, parents, and providers may also be able to see a report summarizing how the patient has been feeling. • Users may occasionally be asked to answer other surveys using the PediQUEST app (for example, parents may be asked about how they are feeling). • How it works 1. Once somebody registers you in the system, you will receive the login credentials over email. These credentials will allow users to complete the sign in process (create a password and password reset questions). 2. After entering the App, you will be able to see whether you have any surveys assigned. Click on survey card to start answering. 3. Users can use the App in multiple languages (only supporting English or Spanish at this time). 4. If the report feature is enabled for you, you will be able to see summary reports for each of the answered surveys. Reports summarize survey answers for the past three months, so they can help understand how the child has been doing lately. 5. Children have told us that looking at the reports helps them talk with their doctors, and parents can better understand how their child is feeling. Reports may also be seen by your clinicians.

Nerbio’s iTOF® app works with the iTOF device; an FDA cleared, quantitative neuromuscular transmission (NMT) monitor for remote monitoring of neuromuscular blocking agents (NMBAs). The iTOF app is designed to make patient monitoring safer, easier to use, and more accurate than ever. The iTOF is the first mobile device-managed, quantitative monitor of NMBAs. The combination of the app and Bluetooth-connected stimulator device allows precise, automated quantitative monitoring of the level of neuromuscular block. Wireless control also improves caregiver safety while maintaining a high-level of patient care. The iTOF system is recommended by leading anesthesiologists and used around the world for accurate NMBA monitoring. ------------------------------- NOTE: This app requires the iTOF device hardware to perform monitoring. Contact nerbio.com for information. iTOF is a registered trademark of Nerbio Medical Software Platforms, Inc. San Jose, California USA. ------------------------------- NOTE: Nerbio’s iTOF is authorized for use in the following countries: USA CHILE COLOMBIA INDIA -------------------------------