Constipation Diary vs OpenEvidence

©NEUROGUT 2018 CONSTIPATION STOOL INSTRUMENT Basic description: The Constipation Stool Instrument (CSI) is a list of patient-reported symptoms for the evaluation of bowel problems associated with constipation. Constipation affects 15% of the US population. Constipation comprises of multiple symptoms that describe the frequency and difficulty with bowel movements. Because of the irregular nature of bowel habit, the multiple and variable symptoms, and difficulty with remembering symptoms as well as recall bias, it is important to prospectively assess patient-reported bowel symptoms, for use in clinical trials, and for the assessment of patients with constipation. Authors: Neurogut Incorporated (USA) Objective: To assess the presence of and severity of patient-reported bowel and abdominal symptoms related to constipation, for use in clinical trials, and assessment of patients with constipation Therapeutic Areas: Gastrointestinal and Digestive System Diseases Pathological conditions, Signs and Symptoms Therapeutic indication: Constipation Dyssynergic defecation Anorectal and Colorectal diseases Type of Clinical Outcome Assessment (COA) Patient Reported Outcome (PRO) assessment Original language English for the USA Bibliographic reference for the original questionnaire: Meduri K, Brown CK, Attaluri A, Valestin J, Rao SSC. Validation of a Prospective Stool Diary for Assessment of Constipation. Neurogastroenterol Motil 2011; 23 (Supplement 1): 21. Administration: The Constipation Stool Instrument (CSI) is a daily, self-administered questionnaire for the assessment of bowel habit. The subject is instructed to fill out all 11 items for one day by responding on each screen presented, and as it relates to each bowel movement. It takes 1 minute to complete this App for each bowel movement. Purpose of survey: To accurately and more completely record each subject’s bowel and stooling habit To better understand the subject’s constipation problem To use the information to improve the health of a patient with constipation Benefits to the Respondent: To improve diagnosis of constipation and to identify the subject’s subtype of constipation To help develop appropriate treatment plan To help develop new treatments

Clinical Decision Support & Medical Search Engine for Healthcare Professionals (NPI Required) OpenEvidence is the most widely used clinical decision support platform and medical search engine among U.S. clinicians. According to independent studies, more American physicians use OpenEvidence than all other AI platforms combined. OpenEvidence is trusted by millions of verified healthcare professionals to make high-stakes clinical decisions at the point of care with answers that are sourced, cited, and grounded in peer-reviewed medical literature. Founded with the mission to organize and expand the world's collective medical knowledge, OpenEvidence is actively used daily by the majority of physicians in the United States. OpenEvidence is free for all verified U.S. clinicians. AN OFFICIAL AI PARTNER OF: The New England Journal of Medicine (NEJM) The Journal of the American Medical Association (JAMA) and its 11 specialty journals National Comprehensive Cancer Network (NCCN) Nature Cochrane Library Wiley WHAT YOU GET: • Specific answers to clinical questions, with every claim cited to its source • 35 million+ peer-reviewed papers, 300+ medical journals, plus FDA and CDC sources • Licensed full text from NEJM, JAMA, Nature, Cochrane, and others • EvidenceGrade™: see the strength of the evidence behind every answer • CME and MOC credits, earned by asking questions • Visits for ambient documentation, Dialer for secure patient calls, and Voice Mode for hands-free answers CONTENT AGREEMENTS AND COLLABORATIONS: American Academy of Family Physicians (AAFP) American College of Cardiology (ACC) American Diabetes Association (ADA) American Academy of Pediatrics (AAP) American College of Obstetricians and Gynecologists (ACOG) American College of Emergency Physicians (ACEP) ASCO Guidelines American Academy of Orthopaedic Surgeons (AAOS) American Academy of Ophthalmology (AAO) American Urological Association (AUA) Plus AAO-HNS, GINA, SNO, SSO, and more. IN USE ACROSS: 10,000+ hospitals and medical centers nationwide, including Mayo Clinic, Mount Sinai, Cedars-Sinai, MSKCC, and Sutter Health. WHY CLINICIANS TRUST US: • HIPAA compliant across the platform • NEJM, JAMA, Nature, and NCCN—official content partners 
 • Tens of millions of clinical consultations per month WHAT CLINICIANS SAY: “OpenEvidence is currently the best AI tool for medical information.” — Dr. Paul Sax, Infectious Disease, Brigham and Women’s Hospital, Review in The New England Journal of Medicine Journal Watch (now NEJM Clinician) “In a morning report, a resident had a question that I didn’t know the answer to, but we were able to open OpenEvidence and get an answer on the spot.” — Dr. Kyle P. Lehenbauer, Minneapolis Veterans Affairs Medical Center “I use OpenEvidence multiple times during the day and every day. I am a better doc because of this. I expand my differential diagnoses and verify the science behind choices of treatments.” — Dr. Sharon E. Martin, Southern Huntingdon Medical Center Important note: OpenEvidence is available only to healthcare professionals. Users must verify their healthcare professional status before using OpenEvidence.