Comparison

CARTOX vs CTCAE 5 Pro

Price, ratings, monetisation and update history for both apps, side by side — with what reviewers say about each.

Head to head
About

CARTOX

This medical app aids clinicians in assessing and managing toxicities associated with cellular therapies, including Cytokine Release Syndrome (CRS) and Immune effector Cell-Associated Neurotoxicity Syndrome (ICANS). It provides grading methods and treatment recommendations for healthcare professionals caring for patients undergoing immune effector cell therapy.

Highlights
  • Toxicity grading
  • CRS assessment
  • ICANS assessment
  • Treatment recommendations
  • Antimicrobial prophylaxis guidance
Features
Read full description

Cellular therapies can be associated with unique, acute toxicities which can be severe or even fatal if not identified early and treated appropriately. Cytokine Release Syndrome (CRS), the most commonly observed toxicity can range in severity from low-grade constitutional symptoms to high-grade syndrome associated with life-threatening multi-organ disfunction. Neurotoxicity, originally termed CRES (CAR-Related Encephalopathy Syndrome) and now updated to ICANS (Immune effector Cell-Associated Neurotoxicity Syndrome) is the second most-common adverse even and can occur concurrently with CRS. A multi-disciplinary working group was formed to address safety issues for patients receiving cellular therapy which led to the development of new grading methods and treatment algorithms that have been incorporated into the CARTOX mobile app. The CARTOX mobile app assists with grading toxicities, managing toxicities and assists with recommendations regarding appropriate antimicrobial prophylaxis for patients who have received immune effector cell therapy. Users are more easily able to determine if the patient is having cytokine release syndrome or neurotoxicity and to grade those toxicities. Intended audience: Clinicians (physicians, nurse practitioners, physician assistants, pharmacists, nurses) who treat/care for patients receiving immune effector cells.

About

CTCAE 5 Pro

This app provides easy access to CTCAE documentation and supports local data storage for enhanced privacy. Premium features include version comparison, advanced note-taking, custom app creation from spreadsheets, and flexible data backup options.

Highlights
  • Streamlined CTCAE Document Access
  • Local Data Storage
  • Version Comparison Tool
  • Advanced Notes Feature
  • Custom App Creation
  • Flexible Backup and Archiving
Features
Read full description

CTCAE 5 Pro is designed to assist in the documentation, review, and reference of CTCAE-related information. This app is intended for informational support and is not designed for medical purposes such as diagnosis, clinical decision-making, or treatment recommendations. Users are responsible for verifying all information and making clinical decisions. ::::::::: Standard features (available to all users) :::::: - Streamlined CTCAE Document Access - Easily navigate CTCAE 5.0 documents using an intuitive interface. - Enhanced privacy with local data storage - protect your data by storing it locally instead of relying on cloud services, ensuring privacy and control. ::::::::: Premium Features (available with subscription) ::::::: - Version Comparison Tool - Easily compare different versions of CTCAE 5.0 and 4.03. - Advanced Notes feature - allows you to record CTCAEs in chronological order. You can also use hashtags and other features to efficiently organize and track notes for important information. - Custom App Creation Feature - Simply import a spreadsheet and convert it into a list app. No programming knowledge is required. - Flexible backup and archiving solution - easily back up and archive data in formats such as XLSX and CSV for versatility and accessibility. - More features are available in the Premium version. Note: With the Premium feature, a minimal number of files are automatically stored in a secure iCloud Drive to resume link information between files. This can be turned off based on user preference.

Screenshots

CARTOX4 screens
CTCAE 5 Pro4 screens

Verdict

The call

CARTOX and CTCAE 5 Pro both sit at 5.0 stars, but that hides the real split: 100% of CARTOX's written reviews are positive against 0% of CTCAE 5 Pro's. CARTOX also leads on in-app purchases (none vs 2). CTCAE 5 Pro's advantage is update cadence (every 5 weeks vs every 20 months) and ratings volume (45 vs 6). On price, rating, ads and device support there is nothing between them.

Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS

CostPrice · In-app purchases · Ads · Monetization

Both are free to download. CTCAE 5 Pro sells 2 in-app purchases, starting at $1.99 per month. CARTOX asks for nothing beyond the download.

ReceptionRating · Positive reviews · Number of ratings

On the App Store both sit at effectively the same score — 5.0 for CARTOX against 4.9 for CTCAE 5 Pro. That said, the two scores are not equally well evidenced: CTCAE 5 Pro has 45 ratings behind it against 6, so its average is the more settled of the two. Written reviews are what separate them: 100% of CARTOX's written reviews are positive against 0% of CTCAE 5 Pro's.

UpkeepUpdate frequency

CARTOX ships an update every 20 months, CTCAE 5 Pro every 5 weeks. The most recent releases landed on November 3, 2026 and November 12, 2026 respectively.

Scorecard6 real differences · 4 level
CARTOX versus CTCAE 5 Pro: the parameters behind the verdict, then further details
ParameterCARTOXCTCAE 5 Pro
PriceFreeFree
Rating5.0 (6 ratings) — better4.9 (45 ratings)
Positive reviews100.0% of reviews — better0.0% of reviews
Number of ratings645 — better
Update frequencyEvery 20 monthsEvery 5 weeks — better
AdsNoNo
In-app purchasesNo — betterYes
MonetizationFree — betterFreemium
DevicesiPhone, iPadiPhone, iPad, iPod — better
Requires iOS26.415.5 — better
Further details — not scored
Size6 MB60 MB
Age rating17+17+
DeveloperMD Anderson Cancer CenterKoichiro Watanabe

Customer experience

CARTOX

All ratings6 ratings
Positive100.0%
Neutral0.0%
Negative0.0%
Written reviews1 reviews
Positive100.0%
Neutral0.0%
Negative0.0%

CTCAE 5 Pro

All ratings42 ratings
Positive97.6%
Neutral0.0%
Negative2.4%
Written reviews1 reviews
Positive0.0%
Neutral0.0%
Negative100.0%

In-app purchases

None

CARTOX

No in-app purchases

2 purchases

CTCAE 5 Pro

Subscriptions2
  • Monthly subscription7 Days trial$1.991 Month
  • Annual subscription7 Days trial$9.991 Year

Questions

Is CARTOX free?
CARTOX is free to download, with no in-app purchases.
Is CTCAE 5 Pro free?
CTCAE 5 Pro is free to download, with in-app purchases available.
Which has better reviews, CARTOX or CTCAE 5 Pro?
CARTOX is rated higher. CARTOX averages 5.0 out of 5 from 6 ratings, while CTCAE 5 Pro averages 4.9 from 45 ratings.
Do CARTOX or CTCAE 5 Pro have ads?
Neither CARTOX nor CTCAE 5 Pro shows ads.
Which is updated more often, CARTOX or CTCAE 5 Pro?
CARTOX ships an update every 20 months, and CTCAE 5 Pro every 5 weeks. Most recently, CARTOX was updated on November 3, 2026 and CTCAE 5 Pro on November 12, 2026.

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