Comparison

Eterna vs Total Biochem

Price, ratings, monetisation and update history for both games, side by side — with what reviewers say about each.

Head to head
About

Eterna

Engage in a citizen science game to design RNA molecules for medical research. Solve puzzles to unlock lab access and contribute to inventing new medicines through challenges.

Highlights
  • Design RNA molecules
  • Solve scientific puzzles
  • Participate in medical research
  • Invent new medicines
  • Unlock lab access
Features
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Eterna is a citizen science game where players learn to design RNA molecules for medical research by solving puzzles. Complete introductory puzzles to unlock lab access and participate in challenges where you can invent medicine!

About

Total Biochem

Master biochemistry with comprehensive study tools, including practice questions, lessons, flashcards, and mock exams. Then, apply your knowledge in a captivating night-shift mystery game where you diagnose patients by analyzing lab results and biochemical pathways.

Highlights
  • 3,300+ Practice Items
  • Lessons for Every Topic
  • Flashcards & Cheat Sheets
  • Mock Exams & Course Map
  • Step-by-step Mechanism Walkthroughs
  • Clinical Mystery Game
  • Lab Analysis Simulation
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A complete biochemistry study app with a bonus night-shift mystery game. Drill every topic and read every pathway — then take a case on the metabolic service, where the same biochemistry is the only thing that tells you what's wrong with the patient. STUDY — EVERYTHING BEFORE THE EXAM (AND AFTER) • 3,300+ Practice Items: 37 drill topics from amino acids to metabolic integration — enzyme kinetics, the pathways, inborn errors, lab methods, the central dogma, and more. Built for course exams, MCAT review, and anyone coming back to biochemistry. • A Lesson for Every Topic: the rules, the traps, and figures drawn the way the exam draws them — kinetics plots and pathway boards you can actually read. • Flashcards & Cheat Sheets: 31 decks and 550+ cards with spaced review, plus pinned reference sheets — the pKa ladder, the control points, the compartments, the quick reference. • Mock Exams & the Course Map: build a practice test with pace presets and exam-style deferred feedback, fix what you missed, and clear units on the Course Map. • Mechanisms, Arrow by Arrow: 15 step-by-step walkthroughs — serine proteases, PLP, TPP, kinases, aldolases — one electron push at a time. PLAY — THE BONUS: A CLINICAL MYSTERY • Work the Night Service: seven floors of a hospital, from the nursery to the exercise lab. Patients arrive with a story — an infant who vomits after fruit juice, a runner with cola-colored urine — and your job is to find the enzyme that failed. • Read the Labs Yourself: order tests against a clock, a reagent budget, and one tube of blood that never refills. The instrument shows you the trace; it never tells you what it means. Misread it, and the wrong number goes in the file. • Place the Block: pin a block on one step of the pathway board and see what the body would do — what piles up, what runs out. When it matches the labs, you call the attending. Three answers, one phone call, no partial credit. • A Hospital with Secrets: every floor has its own story — a swapped formula lot, a visitor after hours, a signature from a clinic that closed last year. Look around, ask the right person, and find out. Free to try. One purchase unlocks everything — no subscriptions, no microtransactions.

Screenshots

Eterna4 screens
Total Biochem4 screens

Verdict

The call

The clearest difference is rating: Total Biochem at 5.0 against Eterna's 3.7. Total Biochem also leads on update cadence (weekly vs every 3 weeks). Eterna's advantage is in-app purchases (none vs 1) and ratings volume (15 vs 1). On price, ads and device support there is nothing between them.

Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS

CostPrice · In-app purchases · Ads · Monetization

Both are free to download. Total Biochem sells 1 one-off in-app purchase. Eterna asks for nothing beyond the download.

ReceptionRating · Positive reviews · Number of ratings

Total Biochem holds the better App Store score, 5.0 against 3.7. That said, the two scores are not equally well evidenced: Eterna has 15 ratings behind it against 1, so its average is the more settled of the two.

UpkeepUpdate frequency

Eterna ships an update every 3 weeks, Total Biochem weekly. Both last shipped on October 24, 2026.

Scorecard6 real differences · 4 level
Eterna versus Total Biochem: the parameters behind the verdict, then further details
ParameterEternaTotal Biochem
PriceFreeFree
Rating3.7 (15 ratings)5.0 (1 ratings) — better
Positive reviews33.3% of reviews—
Number of ratings15 — better1
Update frequencyEvery 3 weeksWeekly — better
AdsNoNo
In-app purchasesNo — betterYes
MonetizationFree — betterFree with in-app purchases
DevicesiPhone, iPad, iPodiPhone, iPad, iPod
Requires iOS13.0 — better15.1
Further details — not scored
Size188 MB63 MB
Age rating12+4+
DeveloperVital Mind MediaSinter Labs LLC

Customer experience

Eterna

All ratings15 ratings
Positive60.0%
Neutral6.7%
Negative33.3%
Written reviews9 reviews
Positive33.3%
Neutral11.1%
Negative55.6%

Total Biochem

All ratings1 ratings
Positive100.0%
Neutral0.0%
Negative0.0%

In-app purchases

None

Eterna

No in-app purchases

1 purchases

Total Biochem

One-time1
  • Full Game$4.99

Questions

Is Eterna free?
Eterna is free to download, with no in-app purchases.
Is Total Biochem free?
Total Biochem is free to download, with in-app purchases available.
Which has better reviews, Eterna or Total Biochem?
Total Biochem is rated higher. Eterna averages 3.7 out of 5 from 15 ratings, while Total Biochem averages 5.0 from 1 ratings.
Do Eterna or Total Biochem have ads?
Neither Eterna nor Total Biochem shows ads.
Which is updated more often, Eterna or Total Biochem?
Eterna ships an update every 3 weeks, and Total Biochem weekly. Most recently, Eterna was updated on October 24, 2026 and Total Biochem on October 24, 2026.

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