Eterna vs Total Biochem
Price, ratings, monetisation and update history for both games, side by side — with what reviewers say about each.
Eterna
Engage in a citizen science game to design RNA molecules for medical research. Solve puzzles to unlock lab access and contribute to inventing new medicines through challenges.
- Design RNA molecules
- Solve scientific puzzles
- Participate in medical research
- Invent new medicines
- Unlock lab access
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Eterna is a citizen science game where players learn to design RNA molecules for medical research by solving puzzles. Complete introductory puzzles to unlock lab access and participate in challenges where you can invent medicine!
Total Biochem
Master biochemistry with comprehensive study tools, including practice questions, lessons, flashcards, and mock exams. Then, apply your knowledge in a captivating night-shift mystery game where you diagnose patients by analyzing lab results and biochemical pathways.
- 3,300+ Practice Items
- Lessons for Every Topic
- Flashcards & Cheat Sheets
- Mock Exams & Course Map
- Step-by-step Mechanism Walkthroughs
- Clinical Mystery Game
- Lab Analysis Simulation
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A complete biochemistry study app with a bonus night-shift mystery game. Drill every topic and read every pathway — then take a case on the metabolic service, where the same biochemistry is the only thing that tells you what's wrong with the patient. STUDY — EVERYTHING BEFORE THE EXAM (AND AFTER) • 3,300+ Practice Items: 37 drill topics from amino acids to metabolic integration — enzyme kinetics, the pathways, inborn errors, lab methods, the central dogma, and more. Built for course exams, MCAT review, and anyone coming back to biochemistry. • A Lesson for Every Topic: the rules, the traps, and figures drawn the way the exam draws them — kinetics plots and pathway boards you can actually read. • Flashcards & Cheat Sheets: 31 decks and 550+ cards with spaced review, plus pinned reference sheets — the pKa ladder, the control points, the compartments, the quick reference. • Mock Exams & the Course Map: build a practice test with pace presets and exam-style deferred feedback, fix what you missed, and clear units on the Course Map. • Mechanisms, Arrow by Arrow: 15 step-by-step walkthroughs — serine proteases, PLP, TPP, kinases, aldolases — one electron push at a time. PLAY — THE BONUS: A CLINICAL MYSTERY • Work the Night Service: seven floors of a hospital, from the nursery to the exercise lab. Patients arrive with a story — an infant who vomits after fruit juice, a runner with cola-colored urine — and your job is to find the enzyme that failed. • Read the Labs Yourself: order tests against a clock, a reagent budget, and one tube of blood that never refills. The instrument shows you the trace; it never tells you what it means. Misread it, and the wrong number goes in the file. • Place the Block: pin a block on one step of the pathway board and see what the body would do — what piles up, what runs out. When it matches the labs, you call the attending. Three answers, one phone call, no partial credit. • A Hospital with Secrets: every floor has its own story — a swapped formula lot, a visitor after hours, a signature from a clinic that closed last year. Look around, ask the right person, and find out. Free to try. One purchase unlocks everything — no subscriptions, no microtransactions.
Screenshots
Verdict
The clearest difference is rating: Total Biochem at 5.0 against Eterna's 3.7. Total Biochem also leads on update cadence (weekly vs every 3 weeks). Eterna's advantage is in-app purchases (none vs 1) and ratings volume (15 vs 1). On price, ads and device support there is nothing between them.
Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS
Both are free to download. Total Biochem sells 1 one-off in-app purchase. Eterna asks for nothing beyond the download.
Total Biochem holds the better App Store score, 5.0 against 3.7. That said, the two scores are not equally well evidenced: Eterna has 15 ratings behind it against 1, so its average is the more settled of the two.
Eterna ships an update every 3 weeks, Total Biochem weekly. Both last shipped on October 24, 2026.
| Parameter | Eterna | Total Biochem |
|---|---|---|
| Price | Free | Free |
| Rating | 3.7 (15 ratings) | 5.0 (1 ratings) — better |
| Positive reviews | 33.3% of reviews | — |
| Number of ratings | 15 — better | 1 |
| Update frequency | Every 3 weeks | Weekly — better |
| Ads | No | No |
| In-app purchases | No — better | Yes |
| Monetization | Free — better | Free with in-app purchases |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Requires iOS | 13.0 — better | 15.1 |
| Further details — not scored | ||
| Size | 188 MB | 63 MB |
| Age rating | 12+ | 4+ |
| Developer | Vital Mind Media | Sinter Labs LLC |
Customer experience
Eterna
Total Biochem
In-app purchases
Eterna
No in-app purchases
Total Biochem
- Full Game$4.99









