Comparison

UpToDate Lexidrug vs APRN and PA’s Complete Guide

Price, ratings, monetisation and update history for both apps, side by side — with what reviewers say about each.

Head to head
About

UpToDate Lexidrug

This app provides comprehensive drug information and tools to aid in safe medication decisions. It offers daily updated clinical information, detailed drug databases, interaction checkers, and medical calculators. It is trusted by healthcare professionals and students for quick access to expert content.

Highlights
  • Daily updated clinical drug information
  • In-depth drug databases with dosing support
  • Comprehensive drug monographs
  • Hundreds of medical calculators
  • Interactive drug interactions checker
  • Offline database access
Features
Currently charting
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UpToDate® Lexidrug™ is the preferred drug reference app, providing industry-leading drug information and tools that support safe and effective medication and therapeutic decisions. View the latest clinical information updated daily by our unparalleled multidisciplinary editorial team that continually reviews the most current evidence available. Used and trusted by pharmacists, physicians, nurses, advanced practice nurses, dentists, and students as an invaluable referential resource. Easily access Lexidrug content directly in the app without needing to download databases onto your device. Our mobile packages are designed to support a variety of roles, offering quick access to expert content and capabilities, including: • In-depth drug databases with detailed dosing support • Comprehensive monographs with adverse reactions information • Hundreds of medical calculators • Interactive drug interactions checker • Ability to store database content for offline use New individual users will receive a one-month free trial to the UpToDate Lexidrug Hospital Pharmacist package. At the end of the free trial, users will automatically be billed a subscription fee of $29.99 per month via their iTunes Account for continuing access. To avoid being charged, users must cancel their free trial at least 24 hours before the end of the trial period. Users can manage settings, cancel subscriptions, or turn off auto-renewal anytime during the subscription period via iTunes Account Settings. Any unused portion of a free trial period, if offered, will be forfeited when the user purchases a subscription to that publication, where applicable.

About

APRN and PA’s Complete Guide

This prescribing reference offers guidance on drug therapy for advanced healthcare providers and students. It includes over 600 diagnoses with detailed pharmacotherapy regimens, lab monitoring, and patient teaching points. Content is updated digitally and accessible offline.

Highlights
  • Over 600 diagnoses with pharmacotherapy regimens
  • Detailed drug information including dosing and FDA pregnancy category
  • Lab values to monitor and patient teaching points
  • Alphabetical diagnosis and drug cross-reference
  • Digital updates and offline access
  • SmartSearch technology for quick information retrieval
Features
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"Try before you buy" - Download the FREE App, which includes sample content. An in-App purchase is required to unlock all content. Updated to deliver the most current standards, this is a unique prescribing reference for APRN students and advanced health care providers in all practice settings who need guidance on prescribing drugs for patients with acute, episodic, and chronic health problems Includes more than 30 new diagnoses with digital updates as needed! Concise, easy to read, and updated throughout, the APRN and PA’s Complete Guide to Prescribing Drug Therapy 2020 delivers pharmacotherapy regimens for more than 600 diagnoses—including over 30 that are new. Listed alphabetically by diagnosis, pharmacotherapy regimens include, for each diagnosis, drug choices listed by generic name, FDA pregnancy category, generic/over-the-counter availability, adult/pediatric dosing regimens, brand names, forms of dosage, and additives. Clinically useful information such as laboratory values to be monitored, patient teaching points, and safety information is interspersed throughout each diagnosis. Additional quick-access features include information presented in convenient table format and an alphabetical cross-reference index of drugs by generic and brand name, with FDA pregnancy category and controlled drug schedule (I, II, III, IV, V). Key Features: * Includes 31 new diagnoses totaling over 600 organized alphabetically * Serves as a quick-access prescribing reference for APRN and PA students and health care providers in all primary care settings * Presents drug information in condensed and summary form for ease of use * Within each diagnosis, drug choices are listed alphabetically by generic /trade name, FDA pregnancy category, adult/pediatric dosing, dose forms, and additives * Delivers guidance on lab values to be monitored, patient education points, and safety information * Includes 30 Appendices with ready access to key drug classifications, FDA Pregnancy Categories, US Schedule of Controlled Substances, Immunization Schedules, Contraceptive Guidance, categories Anti-Infectives, and more! * Offers brand/generic cross-reference No internet connection is required to access the content after the initial download. Find information quickly using powerful SmartSearch technology. Search part of term for those hard to spell medical terms. Content licensed from printed ISBN 13: 9780826179333 SUBSCRIPTION : Please choose an auto renewable subscription plan to receive content access & continuous updates. Your subscription automatically renews as per your plan, so you always have the latest content. Yearly auto-renewing payments-$39.99 Payment will be charged to your iTunes Account at confirmation of purchase. Subscription automatically renews unless auto-renew is turned off at least 24-hours before the end of the current period. Subscription may be managed by the user & auto-renewal can be disabled at any time by going to your device “Settings” and tapping “iTunes & App Store”. Any unused portion of a free trial period will be forfeited when you purchase a subscription, where applicable. If you have any questions or comments, email us any time: customersupport@skyscape.com or call 508-299-30000 Privacy Policy-https://www.skyscape.com/terms-of-service/privacypolicy.aspx Terms and Conditions-https://www.skyscape.com/terms-of-service/licenseagreement.aspx Editor(s): Mari J. Wirfs, PhD, MN, RN, APRN, ANP-BC, FNP-BC, CNE Publisher: Springer Publishing Company

Screenshots

UpToDate Lexidrug4 screens
APRN and PA’s Complete Guide4 screens

Verdict

The call

The clearest difference is review sentiment: UpToDate Lexidrug at 40% against APRN and PA’s Complete Guide's 0%. UpToDate Lexidrug also leads on ads (none vs shown) and ratings volume (6.1K vs 25). APRN and PA’s Complete Guide's advantage is monetization model (free with in-app purchases vs subscription) and iOS requirement (13.0 vs 16.0). On price, in-app purchases and device support there is nothing between them.

Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS

CostPrice · In-app purchases · Ads · Monetization

Both are free to download. UpToDate Lexidrug sells 2 in-app purchases, starting at $29.99 per month and APRN and PA’s Complete Guide sells 2 in-app purchases, starting at $39.99 per year. Whichever you choose, the download price is not the number that matters.

ReceptionRating · Positive reviews · Number of ratings

UpToDate Lexidrug holds the better App Store score, 4.7 against 4.5. That said, the two scores are not equally well evidenced: UpToDate Lexidrug has 6.1K ratings behind it against 25, so its average is the more settled of the two. Written reviews point the same way: 40% of UpToDate Lexidrug's written reviews are positive against 0% of APRN and PA’s Complete Guide's.

UpkeepUpdate frequency

UpToDate Lexidrug ships an update every 2 months, APRN and PA’s Complete Guide every 8 months. The most recent releases landed on November 10, 2026 and November 3, 2026 respectively.

Scorecard8 real differences · 3 level
UpToDate Lexidrug versus APRN and PA’s Complete Guide: the parameters behind the verdict, then further details
ParameterUpToDate LexidrugAPRN and PA’s Complete Guide
PriceFreeFree
Rating4.7 (6.1K ratings) — better4.5 (25 ratings)
Positive reviews39.8% of reviews — better0.0% of reviews
Number of ratings6.1K — better25
Update frequencyEvery 2 months — betterEvery 8 months
AdsNo — betterYes
In-app purchasesYesYes
MonetizationSubscriptionFree with in-app purchases — better
Best chart rank#20 — better—
DevicesiPhone, iPadiPhone, iPad, iPod — better
Requires iOS16.013.0 — better
Further details — not scored
Size67 MB148 MB
Age rating17+17+
DeveloperLexi-CompSkyscape Medpresso Inc

Customer experience

UpToDate Lexidrug

All ratings5,774 ratings
Positive93.7%
Neutral1.6%
Negative4.7%
Written reviews231 reviews
Positive39.8%
Neutral10.8%
Negative49.4%

APRN and PA’s Complete Guide

All ratings24 ratings
Positive87.5%
Neutral0.0%
Negative12.5%
Written reviews2 reviews
Positive0.0%
Neutral0.0%
Negative100.0%

Bugs and requests

UpToDate Lexidrug

Reported bugs

3 issues
  • App freezing when trying to access certain features
  • Databases not downloading or updating properly
  • Inconsistent behavior across iOS versions

Requested features

3 requests
  • Ability to customize database order and priority
  • Improved offline functionality and background updates
  • More user-friendly interface and navigation

APRN and PA’s Complete Guide

Not enough reviews yet to summarise bugs or requests.

In-app purchases

2 purchases

UpToDate Lexidrug

Subscriptions2
  • Lexicomp Professional Package14 Days trial$29.991 Month
  • Lexi-COMPLETE14 Days trial$29.991 Month
2 purchases

APRN and PA’s Complete Guide

Subscriptions1
  • APRN & PA’s Complete Guide$39.991 Year
One-time1
  • APRN & PA’s Complete Guide$39.99

Questions

Is UpToDate Lexidrug free?
UpToDate Lexidrug is free to download, with in-app purchases available.
Is APRN and PA’s Complete Guide free?
APRN and PA’s Complete Guide is free to download, with in-app purchases available.
Which has better reviews, UpToDate Lexidrug or APRN and PA’s Complete Guide?
UpToDate Lexidrug is rated higher. UpToDate Lexidrug averages 4.7 out of 5 from 6.1K ratings, while APRN and PA’s Complete Guide averages 4.5 from 25 ratings.
Do UpToDate Lexidrug or APRN and PA’s Complete Guide have ads?
APRN and PA’s Complete Guide shows ads; UpToDate Lexidrug does not.
Which is updated more often, UpToDate Lexidrug or APRN and PA’s Complete Guide?
UpToDate Lexidrug ships an update every 2 months, and APRN and PA’s Complete Guide every 8 months. Most recently, UpToDate Lexidrug was updated on November 10, 2026 and APRN and PA’s Complete Guide on November 3, 2026.

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