Comparison

Sepsis Clinical Guide vs Synt®

Price, ratings, monetisation and update history for both apps, side by side — with what reviewers say about each.

Head to head
About

Sepsis Clinical Guide

This app provides busy health professionals with essential management information for sepsis, based on the latest practice guidelines. It offers quick access to definitions, diagnostic criteria, and treatment protocols at the point of care. It also includes a community forum for clinicians to exchange ideas and collaborate on clinical topics.

Highlights
  • Latest sepsis definitions and diagnostic criteria
  • Management guidelines from Surviving Sepsis Campaign
  • Information on epidemiology and pathophysiology
  • Guidance on antibiotic therapy
  • Pediatric and neonatal sepsis management
  • Clinical community forum for collaboration
Features
Read full description

Sepsis Clinical Guide now includes access the new ESCAVO Clinical Community, a forum where clinicians can exchange ideas, ask questions and collaborate on sepsis and other clinical topics. Sepsis is a serious systemic infection that can quickly lead to circulatory shock, organ failure and death if inappropriately treated. In 2017, over 2 million people were admitted to US hospitals for sepsis (#1 cause of index admissions) at a total aggregate cost to the US healthcare system of $38.2 billion dollars (#1 most expensive condition), according to an AHRQ report. Over 270,000 people die of sepsis in the US every year, more than from prostate cancer, breast cancer and AIDS combined. Despite its large toll on public health, public awareness of this condition is poor and the quality of treatment is highly variable often due to delayed recognition and treatment. In sepsis, time is of the essence. Successful treatment hinges on prompt recognition of symptoms, correct antibiotic administration, and hemodynamic stabilization. Lack of appropriate sepsis management knowledge at the bedside leads to delayed symptom recognition, serious complications, medical errors, increased treatment costs, and avoidable morbidity and mortality. For this reason, we created this app to provide busy health professionals with essential management information based on the latest practice guidelines in a format that is easily accessible at the point of care. The Sepsis app was developed on the ESCAVO mobile publishing platform created specifically for mobile publishing of scientific content. The platform features an intuitive user interface, search, annotation and bookmarking functions, and calculator support. All content is extensively referenced and footnoted where appropriate. Clinical topics covered in the Sepsis app include: - Updated with the latest definitions, diagnostic criteria, and management guidelines including the 2016 Sepsis-3 definitions and the latest Surviving Sepsis Campaign (SSC) guidelines - Epidemiology, risk factors and pathophysiology of sepsis and septic shock - Common differentials and etiology, guidelines on performing appropriate H&P and workups - Management of common causes including hospital-acquired pneumonia (HAP), ventilator-acquired pneumonia (VAP) and intra-abdominal infections - Sepsis management bundles, early goal-directed therapy, hemodynamic management, adjunctive therapies, mechanical ventilation of sepsis-induced ARDS, and other essential management guidelines from the SSC and the American Thoracic Society (ATS) - Antibiotic therapy including specific guidelines for the treatment of HAP from ATS and the Infectious Diseases Society of America (IDSA) - Guidance on the prevention, recognition and treatment of Clostridium difficile based on the latest IDSA guidelines - Information on the diagnosis and management of pediatric and neonatal sepsis including the management of pediatric fever, important differences from adult sepsis, management of sepsis-induced persistent pulmonary hypertension of the newborn (PPHN), empiric antibiotic treatment recommendations for GBS infections, interventions in pediatric septic shock, and other pediatric-specific information - Important score calculators including the Sequential Organ Failure Assessment (SOFA), quick-SOFA, SIRS, APACHE II, Multiple Organ Dysfunction Score (MODS), the Simplified Acute Physiology Score (SAPS) II, National Early Warning Score (NEWS), the Clinical Pulmonary Infection (CPI) score, the Inferior Vena Cava Collapsibility Index, and others - Drug administration information for the management of sepsis including antibacterial and antifungal antibiotics, the latest drugs for emerging multi-drug resistant organisms, adrenergic and other vasoactive agents, corticosteroids and diuretics - Relevant COVID-19 management information Recommended by: - HealthTap.com - MDLinx.com - imedicalapps.com - The ED Trauma Critical Care Blog (edtcc.com)

About

Synt®

This clinical super app synthesizes patient-specific medical information, offering diagnostic decision support and dynamic data for physicians. It aids in diagnosis by augmenting human intelligence with structured medical knowledge and analytics.

Highlights
  • Patient-specific medical information processing
  • Diagnostic decision support
  • Synthetic knowledge and dynamic data points
  • Integration with MediCalc® ia
  • 800+ Disease/Problem Profiles
  • 120+ Differential Diagnosis Sets
  • 1000+ Labs & Tests
Features
Read full description

ScyMed proudly introduces the new Synt® 1.3, an expert system representing the most innovative Clinical super App, for patient-specific medical information processing, synthetic knowledge and dynamic data points for reference, analytics, diagnostic decision support & patient care. In the era of information overload, rising complexity of healthcare and huge cognitive burden for physicians, the most critical challenge they encounter when making a Diagnosis is synthesizing complex patient data (hence its name). Synt® supports the Diagnostic Process achieving synergy between Human Intelligence and Intelligence Augmentation (IA) to reach Diagnostic excellence. The system is fully integrated (data level), with ScyMed's killerApp MediCalc® ia, our trusted and highly acclaimed Medical Calculator System™, with more than half a million users worldwide (since 1999). Featuring mCalx™ (1 panel, 150+ equations/scores). FEATURING: --------------------------------------- 800 Diseases/Problems PROFILES 120+ Differential Diagnosis (DDx) SETS 1000+ Labs & Tests 500+ Equations & Scores 800+ Signs & Symptoms 250+ Drugs 100,000+ DISEASE DATA POINTS (Custom, Disease-specific Flowsheets, any combination) --------------------------------------- Introductory Price: FREE (limited time) +For Physicians, Residents, Med students, PAs and NPs. +Developed by Board-certified physicians in the US. +Trusted resource with proven & reliable data processing. +Fastest & most efficient access to info +intuitive user interface +best Data synthesis & visualization +Evidence-based and fully referenced -------------------------------- DDx Expert System Synt® is a Diagnostic Intelligence Augmentation (IA & AI) application. A rules-based expert system for Clinical Diagnosis. The logic of algorithms and the medical knowledge have been manually encoded. Every bit of data has been meticulously structured and programmed. The diagnostic logic is clear and transparent (no blackbox).  Synt® doesn't rely on LLM or Natural Language Processing at this time. Data: from Static Text to Dynamic Flowsheet Synt® is a breakthrough, it changes access to a wealth of medical knowledge from the static isolated text (book, document) to a connected, custom dynamic flowsheet (software, flowchart). It allows users to visualize and compare, side-by-side, all disease information at the deepest granular level (ad lib), including Signs, Symptoms, Labs, Tests, parameters, equations, scores, etc. The user controls the panels, selects Diseases, changes views, filters data and in the DDx+™ Tool can highlight patient-specific findings for visual efficiency. Big Data. Structured. Synt® is structured 'Big Data', organized, classified, accurate, synthesized. The largest virtual medical information matrix (flowsheet) ever developed, >2 million cells (>800 diseases by >2200 S&S, Labs, Tests, parameters, eqs, scores in the rows). Cells are populated when pertinent and indicate expected findings. Content, Function & UX/UI Synt® incorporates a wealth of synthesized info & knowledge on Diseases & Problems. Data Point cells include links to disease info, pearls, definitions, dynamic tables, classifications, normall values, converters (SI), Stats, Se, Sp, etc. Synt® functionality is highly versatile, it offers multiple views of data (search, filters, selections by Dz or SLT, processing, customization, etc.). The dark UI is elegant & visually efficient, UX is superb. ------------------------- Synt® Tools: DDx+™ (Differential Diagnosis +™) From Dx to specific Dx Noso™ Tool (Disease Data Points Tool) For DDx wayfinding SLT Checkr™ (S&S, Labs, Tests Checker™ Tool) - Symptom, Sign, Lab, Test Checker From Symptom (SLT) to Dx or Drug Drug effx™ Tool (Drug effects) From Drug to symptoms (SLT) & vice versa Synt® emphasis is on Differential Diagnosis (DDx), not on the presentation, Dx (label), Rx or Management. Synt® is NOT a Diagnostic program, it is a DDx Decision Support Tool.

Screenshots

Sepsis Clinical Guide4 screens
Synt®4 screens

Verdict

The call

The clearest difference is update cadence: Synt® at every 2 weeks against Sepsis Clinical Guide's every 4 months. Sepsis Clinical Guide's advantage is ratings volume (303 vs 13). On price, rating, review sentiment and ads there is nothing between them.

Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS

CostPrice · In-app purchases · Ads · Monetization

Both are free to download. Neither carries in-app purchases, so what you see is what you pay.

ReceptionRating · Positive reviews · Number of ratings

Synt® holds the better App Store score, 5.0 against 4.8. That said, the two scores are not equally well evidenced: Sepsis Clinical Guide has 303 ratings behind it against 13, so its average is the more settled of the two. Written reviews point the same way: 94% of Sepsis Clinical Guide's written reviews are positive against 100% of Synt®'s.

UpkeepUpdate frequency

Sepsis Clinical Guide ships an update every 4 months, Synt® every 2 weeks. The most recent releases landed on November 6, 2026 and November 2, 2026 respectively.

Scorecard2 real differences · 8 level
Sepsis Clinical Guide versus Synt®: the parameters behind the verdict, then further details
ParameterSepsis Clinical GuideSynt®
PriceFreeFree
Rating4.8 (303 ratings)5.0 (13 ratings) — better
Positive reviews94.4% of reviews100.0% of reviews — better
Number of ratings303 — better13
Update frequencyEvery 4 monthsEvery 2 weeks — better
AdsNoNo
In-app purchasesNoNo
MonetizationFreeFree
DevicesiPhone, iPad, iPodiPhone, iPad, iPod
Requires iOS12.0 — better13.0
Further details — not scored
Size139 MB84 MB
Age rating17+17+
DeveloperEscavo, IncScyMed, Inc

Customer experience

Sepsis Clinical Guide

All ratings304 ratings
Positive96.1%
Neutral3.6%
Negative0.3%
Written reviews18 reviews
Positive94.4%
Neutral0.0%
Negative5.6%

Synt®

All ratings13 ratings
Positive100.0%
Neutral0.0%
Negative0.0%
Written reviews7 reviews
Positive100.0%
Neutral0.0%
Negative0.0%

Bugs and requests

Sepsis Clinical Guide

Reported bugs

1 issue
  • App freezes on initial update and won't open

Requested features

1 request
  • Ideal body weight chart and formula

Synt®

Not enough reviews yet to summarise bugs or requests.

In-app purchases

None

Sepsis Clinical Guide

No in-app purchases

None

Synt®

No in-app purchases

Questions

Is Sepsis Clinical Guide free?
Sepsis Clinical Guide is free to download, with no in-app purchases.
Is Synt® free?
Synt® is free to download, with no in-app purchases.
Which has better reviews, Sepsis Clinical Guide or Synt®?
Synt® is rated higher. Sepsis Clinical Guide averages 4.8 out of 5 from 303 ratings, while Synt® averages 5.0 from 13 ratings.
Do Sepsis Clinical Guide or Synt® have ads?
Neither Sepsis Clinical Guide nor Synt® shows ads.
Which is updated more often, Sepsis Clinical Guide or Synt®?
Sepsis Clinical Guide ships an update every 4 months, and Synt® every 2 weeks. Most recently, Sepsis Clinical Guide was updated on November 6, 2026 and Synt® on November 2, 2026.

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