Comparison

STI Tx Guide vs CDC Yellow Book

Price, ratings, monetisation and update history for both apps, side by side — with what reviewers say about each.

Head to head
About

STI Tx Guide

Provides healthcare professionals with up-to-date, evidence-based recommendations for the prevention, diagnosis, and treatment of sexually transmitted infections. Features include clinical care guidance, sexual history resources, and patient materials for effective patient management.

Highlights
  • STI prevention recommendations
  • Diagnosis guidance
  • Treatment protocols
  • Clinical care assistance
  • Sexual history resources
  • Patient management tools
Features
Read full description

The new app offers quick and easy access to streamlined STI prevention, diagnosis, and treatment recommendations. The user-friendly interface includes more clinical care guidance, sexual history resources, patient materials, and other features to assist with patient management. The STI Treatment (Tx) Guidelines mobile app serves as a quick reference guide for doctors and related parties on the identification of and treatment for sexually transmitted diseases (STDs). The full STI Treatment Guidelines (cdc.gov) can be accessed at https://www.cdc.gov/std/treatment-guidelines/default.htm. The guidelines provide current evidence-based prevention, diagnostic and treatment recommendations that replace the 2015 guidance. The recommendations are intended to be a source for clinical guidance. Healthcare providers should always assess patients based on their clinical circumstances and local burden. DISCLAIMER THE MATERIALS EMBODIED IN THIS SOFTWARE IS PROVIDED TO YOU "AS-IS" AND WITHOUT WARRANTY OF ANY KIND, EXPRESS, IMPLIED OR OTHERWISE, INCLUDING WITHOUT LIMITATION, ANY WARRANTY OF FITNESS FOR A PARTICULAR PURPOSE. IN NO EVENT SHALL THE CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC) OR THE UNITED STATES (U.S.) GOVERNMENT BE LIABLE TO YOU OR ANYONE ELSE FOR ANY DIRECT, SPECIAL, INCIDENTAL, INDIRECT OR CONSEQUENTIAL DAMAGES OF ANY KIND, OR ANY DAMAGES WHATSOEVER, INCLUDING WITHOUT LIMITATION, LOSS OF PROFIT, LOSE OF USE, SAVINGS OR REVENUE, OR THE CLAIMS OF THIRD PARTIES, WHETHER OR NOT CDC OR THE U.S. GOVERNMENT HAS BEEN ADVISED OF THE POSSIBILITY OF SUCH LOSS, HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, ARISING OUT OF OR IN CONNECTION WITH THE POSSESSION, USE OR PERFORMANCE OF THIS SOFTWARE.

About

CDC Yellow Book

Access the U.S. government's most current travel health guidelines, including vaccine recommendations and destination-specific advice. This app offers comprehensive information for staying healthy abroad, with features like search, notes, and favorites.

Highlights
  • Pre-travel vaccinations and preventative care
  • Destination-specific guidelines
  • Advice for travelers with specific health needs
  • Full text search
  • Custom notes and highlights
  • Reference maps, tables, and charts
Features
Read full description

**U.S. Government’s Most Current and Trusted Travel Health Guidelines** Preview, Buy, or Sign In using this app. FREE PREVIEW – Experience the Yellow Book to see the value of having trusted travel information when and where it's needed. ABOUT YELLOW BOOK The fully revised and updated 2020 CDC Yellow Book app delivers the U.S. government’s most current travel health guidelines, including pre-travel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. Authored by a team of the world’s most esteemed travel medicine experts, this app best codifies the U.S. Government’s latest travel guidelines to staying healthy anywhere in the world. Review dedicated topics on emerging infectious disease threats such as Zika, Ebola, and MERS, new cholera vaccine recommendations, updated guidance on the use of antibiotics to treat traveler’s diarrhea, special considerations for unique types of travel (i.e. wilderness expeditions, work-related travel, and studying abroad), and fully revised advice for specific destinations in international travel. FEATURES • Pre-travel vaccinations and preventative care • Destination specific guidelines with sections on Cuba and Burma • Advice for travelers with specific health needs (pregnant women, travelers with chronic illness, etc.) • Practical tips for last minute or resource limited travelers • Recommendations for air crews, humanitarian workers, missionaries, and others who provide care and support overseas • Easy to use reference maps, tables, and charts • Notes for making custom notes and highlights within entries • Full Text Search to find specific topics quickly • "Favorites" for bookmarking important topics EDITOR-IN-CHIEF: Gary W. Brunette Publisher: Oxford University Press Powered by: Unbound Medicine Unbound Privacy Policy: www.unboundmedicine.com/privacy Unbound Terms of Use: https://www.unboundmedicine.com/end_user_license_agreement

Screenshots

STI Tx Guide4 screens
CDC Yellow Book4 screens

Verdict

The call

The clearest difference is rating: CDC Yellow Book at 4.2 against STI Tx Guide's 3.5. STI Tx Guide's advantage is in-app purchases (none vs 2) and update cadence (every 2 months vs every 21 months). On price, ratings volume, ads and device support there is nothing between them.

Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS

CostPrice · In-app purchases · Ads · Monetization

Both are free to download. CDC Yellow Book sells 1 one-off in-app purchase. STI Tx Guide asks for nothing beyond the download.

ReceptionRating · Positive reviews · Number of ratings

CDC Yellow Book holds the better App Store score, 4.2 against 3.5. Both are backed by a comparable volume of ratings — 36 and 69 respectively. Written reviews complicate that: 36% of STI Tx Guide's written reviews are positive against 20% of CDC Yellow Book's, so the app with the better star average is not the one people write more warmly about.

UpkeepUpdate frequency

STI Tx Guide ships an update every 2 months, CDC Yellow Book every 21 months. The most recent releases landed on October 23, 2026 and October 24, 2026 respectively.

Scorecard5 real differences · 5 level
STI Tx Guide versus CDC Yellow Book: the parameters behind the verdict, then further details
ParameterSTI Tx GuideCDC Yellow Book
PriceFreeFree
Rating3.5 (36 ratings)4.2 (69 ratings) — better
Positive reviews35.7% of reviews — better20.0% of reviews
Number of ratings3669 — better
Update frequencyEvery 2 months — betterEvery 21 months
AdsNoNo
In-app purchasesNo — betterYes
MonetizationFree — betterFree with in-app purchases
DevicesiPhone, iPodiPhone, iPad, iPod — better
Requires iOS15.015.0
Further details — not scored
Size36 MB10 MB
Age rating12+17+
DeveloperCenters For Disease Control and PreventionUnbound Medicine, Inc.

Customer experience

STI Tx Guide

All ratings36 ratings
Positive63.9%
Neutral2.8%
Negative33.3%
Written reviews14 reviews
Positive35.7%
Neutral7.1%
Negative57.1%

CDC Yellow Book

All ratings68 ratings
Positive80.9%
Neutral1.5%
Negative17.6%
Written reviews10 reviews
Positive20.0%
Neutral0.0%
Negative80.0%

In-app purchases

None

STI Tx Guide

No in-app purchases

1 purchases

CDC Yellow Book

One-time1
  • CDC Yellow Book2 variants$29.99

Questions

Is STI Tx Guide free?
STI Tx Guide is free to download, with no in-app purchases.
Is CDC Yellow Book free?
CDC Yellow Book is free to download, with in-app purchases available.
Which has better reviews, STI Tx Guide or CDC Yellow Book?
CDC Yellow Book is rated higher. STI Tx Guide averages 3.5 out of 5 from 36 ratings, while CDC Yellow Book averages 4.2 from 69 ratings.
Do STI Tx Guide or CDC Yellow Book have ads?
Neither STI Tx Guide nor CDC Yellow Book shows ads.
Which is updated more often, STI Tx Guide or CDC Yellow Book?
STI Tx Guide ships an update every 2 months, and CDC Yellow Book every 21 months. Most recently, STI Tx Guide was updated on October 23, 2026 and CDC Yellow Book on October 24, 2026.

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