Protocell Defender vs Immunity
Price, ratings, monetisation and update history for both games, side by side — with what reviewers say about each.
Protocell Defender
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Protocell Defender - Cellular Tower Defense Zoom in to the microscopic scale and defend your cellular nucleus against waves of pathogens: bacteria, viruses, camouflaged prions, life-stealing parasites, and worse. GAMEPLAY • 12 unique maps, from simple gut paths to the 3-lane final stand • 7 specialized towers: Spike Cell, Membrane Wall, Mitochondria, Lysosome, Ribosome, Flagellum, Antibody • Each tower evolves on 2 distinct paths (Path A / Path B) with cross-path mutations • 20 waves per game, boss every 4 waves • 3 difficulty modes: Normal, Hard, Impossible ENEMIES 16+ types with unique mechanics: regenerating armor, camouflage, death-split, tower disabling, life-stealing, damage-reduction auras. STRATEGY • Synergies between adjacent towers (Supercharged, Acid Trap, Hunter, Efficient) • 4 targeting modes per tower: First, Closest, Strongest, Weakest • Punishing ATP economy: every placement counts IN-APP PURCHASES (optional) • ATP Boost +50%, +5 Starting Lives, Quick Save, 5x Speed • All toggleable in-game and disabled in Impossible mode to preserve the challenge No ads. No pay-to-win. Just a demanding tower defense that respects your time.
Immunity
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YOU ARE THE LAST LINE OF DEFENSE. Play as a macrophage — the immune system's most powerful cell — and fight through 10 zones of the human body in this biology-based action roguelite. THE BODY IS UNDER ATTACK. From the Lymph Node to the Heart, real pathogens have invaded every organ. Bacteria. Parasites. Viruses. Kidney stones. Blood clots. Each zone brings new enemies grounded in actual cell biology — every creature, ability, and mechanic is based on how the immune system really works. BUILD YOUR IMMUNE RESPONSE. Every run is different. Collect 27+ adaptations and abilities as you progress — Cytokine Burst, Fever Mode, Phagocytosis, Neutrophil Swarm, Complement Cascade, and more. Stack upgrades. Build synergies. Adapt to every threat. 10 ZONES. 10 BOSSES. ▸ Lymph Node — face the Dormant Sentinel ▸ Lungs — battle the Pneumonia Mass ▸ Bloodstream — confront the Sepsis Herald ▸ Stomach — destroy H. Pylori Overlord ▸ Brain — survive the Neuroinflammation Prime ▸ Liver — fight the Cirrhosis Node ▸ Small Intestine — stop the Tapeworm Queen ▸ Large Intestine — dismantle the Bacterial Megacolony ▸ Kidneys — shatter the Nephrolithic Golem ▸ Heart — expel the Myocardial Invader THEN FACE THE FINAL BOSS. Cancer. The body's own cells gone wrong. A corrupted mirror of yourself. Three phases. Endless copies. No easy victory. ROGUELITE THAT RESPECTS YOUR TIME. ▸ Quick runs — each zone takes minutes ▸ Permanent upgrades carry between runs ▸ No energy systems. No paywalls. Play anytime. ▸ Every run feels different — 27+ items, abilities, and upgrades ▸ One more run feeling that turns five minutes into an hour LEARN WHILE YOU PLAY. Every enemy is a real pathogen. Every ability is a real immune response. Immunity is the only roguelite built on actual immunology — making it genuinely educational without ever feeling like homework. ▸ E. coli that groups and reforms ▸ Fibrin clots that regenerate HP ▸ Calcium oxalate crystals with mineral armor ▸ Platelet swarms that recruit more platelets ▸ A Cancer boss that proliferates when damaged Can the immune system hold?
Screenshots
Verdict
Protocell Defender and Immunity are too close to call on the numbers: across 5 compared parameters — price, ads, in-app purchases and device support among them — neither pulls far enough ahead to decide it. What separates them is feature set and interface, not measurable difference.
Scored on Price · Rating · Positive reviews · Number of ratings · Update frequency · Ads · In-app purchases · Monetization · Best chart rank · Devices · Requires iOS
Both are free to download. Neither carries in-app purchases, so what you see is what you pay.
| Parameter | Protocell Defender | Immunity |
|---|---|---|
| Price | Free | Free |
| Rating | — | 1.0 (1 ratings) — better |
| Number of ratings | — | 1 — better |
| Ads | No | No |
| In-app purchases | No | No |
| Devices | iPhone, iPad, iPod | iPhone, iPad, iPod |
| Requires iOS | 14.0 — better | 14.3 |
| Further details — not scored | ||
| Size | 66 MB | 343 MB |
| Age rating | 12+ | 4+ |
| Developer | Pierre-Julien AVRIL | DALTON SANDOR DRISCOLL |
In-app purchases
Protocell Defender
No in-app purchases
Immunity
No in-app purchases









