Immunity vs PATHOGENEER

YOU ARE THE LAST LINE OF DEFENSE. Play as a macrophage — the immune system's most powerful cell — and fight through 10 zones of the human body in this biology-based action roguelite. THE BODY IS UNDER ATTACK. From the Lymph Node to the Heart, real pathogens have invaded every organ. Bacteria. Parasites. Viruses. Kidney stones. Blood clots. Each zone brings new enemies grounded in actual cell biology — every creature, ability, and mechanic is based on how the immune system really works. BUILD YOUR IMMUNE RESPONSE. Every run is different. Collect 27+ adaptations and abilities as you progress — Cytokine Burst, Fever Mode, Phagocytosis, Neutrophil Swarm, Complement Cascade, and more. Stack upgrades. Build synergies. Adapt to every threat. 10 ZONES. 10 BOSSES. ▸ Lymph Node — face the Dormant Sentinel ▸ Lungs — battle the Pneumonia Mass ▸ Bloodstream — confront the Sepsis Herald ▸ Stomach — destroy H. Pylori Overlord ▸ Brain — survive the Neuroinflammation Prime ▸ Liver — fight the Cirrhosis Node ▸ Small Intestine — stop the Tapeworm Queen ▸ Large Intestine — dismantle the Bacterial Megacolony ▸ Kidneys — shatter the Nephrolithic Golem ▸ Heart — expel the Myocardial Invader THEN FACE THE FINAL BOSS. Cancer. The body's own cells gone wrong. A corrupted mirror of yourself. Three phases. Endless copies. No easy victory. ROGUELITE THAT RESPECTS YOUR TIME. ▸ Quick runs — each zone takes minutes ▸ Permanent upgrades carry between runs ▸ No energy systems. No paywalls. Play anytime. ▸ Every run feels different — 27+ items, abilities, and upgrades ▸ One more run feeling that turns five minutes into an hour LEARN WHILE YOU PLAY. Every enemy is a real pathogen. Every ability is a real immune response. Immunity is the only roguelite built on actual immunology — making it genuinely educational without ever feeling like homework. ▸ E. coli that groups and reforms ▸ Fibrin clots that regenerate HP ▸ Calcium oxalate crystals with mineral armor ▸ Platelet swarms that recruit more platelets ▸ A Cancer boss that proliferates when damaged Can the immune system hold?

Your plan. Their pandemic. Engineer a deadly strain, plot its evolution and release it into the world. Watch infections spread across the map as your creation breaks into new hosts. PATHOGENEER puts you in control of a fictional pathogen. Shape a branching genome, adapt to new environments and discover which hosts your strain can reach. A promising start can stall at a barrier. The right mutation can open another route. MAKE IT YOURS Choose genes that shape spread, survival, resistance and host jumping. Unlock new modifications through successful infections and build a strain with its own strengths and tradeoffs. CROSS THE HOST BARRIER Begin with plants and unlock insects, birds, land animals and humans. Explore different targets and habitats as your creation finds new ways to spread. CHOOSE YOUR GROUND ZERO Pick a starting location. Climate, habitat and host conditions affect whether your strain gains a foothold or struggles to establish itself. WATCH THE CASCADE Follow infection fronts across the map, switch host layers and zoom in on the action. Make decisions during a run as opportunities and barriers emerge. BUILD YOUR NEXT BREAKTHROUGH Keep memorable strains, carry successful genes into descendants and chase a stronger cascade. Open Threads suggest a next step for your lineage. Share your specimen, a standout spread or the stats from a run you are proud of. Where will your next creation take hold? PATHOGENEER is a fictional ecology strategy game inspired by real-world environments and habitats. Its organisms, mutations and outcomes are designed for entertainment, not real-world pathogen engineering.