Immunity vs PATHOGENEER

YOU ARE THE LAST LINE OF DEFENSE. Play as a macrophage — the immune system's most powerful cell — and fight through 10 zones of the human body in this biology-based action roguelite. THE BODY IS UNDER ATTACK. From the Lymph Node to the Heart, real pathogens have invaded every organ. Bacteria. Parasites. Viruses. Kidney stones. Blood clots. Each zone brings new enemies grounded in actual cell biology — every creature, ability, and mechanic is based on how the immune system really works. BUILD YOUR IMMUNE RESPONSE. Every run is different. Collect 27+ adaptations and abilities as you progress — Cytokine Burst, Fever Mode, Phagocytosis, Neutrophil Swarm, Complement Cascade, and more. Stack upgrades. Build synergies. Adapt to every threat. 10 ZONES. 10 BOSSES. ▸ Lymph Node — face the Dormant Sentinel ▸ Lungs — battle the Pneumonia Mass ▸ Bloodstream — confront the Sepsis Herald ▸ Stomach — destroy H. Pylori Overlord ▸ Brain — survive the Neuroinflammation Prime ▸ Liver — fight the Cirrhosis Node ▸ Small Intestine — stop the Tapeworm Queen ▸ Large Intestine — dismantle the Bacterial Megacolony ▸ Kidneys — shatter the Nephrolithic Golem ▸ Heart — expel the Myocardial Invader THEN FACE THE FINAL BOSS. Cancer. The body's own cells gone wrong. A corrupted mirror of yourself. Three phases. Endless copies. No easy victory. ROGUELITE THAT RESPECTS YOUR TIME. ▸ Quick runs — each zone takes minutes ▸ Permanent upgrades carry between runs ▸ No energy systems. No paywalls. Play anytime. ▸ Every run feels different — 27+ items, abilities, and upgrades ▸ One more run feeling that turns five minutes into an hour LEARN WHILE YOU PLAY. Every enemy is a real pathogen. Every ability is a real immune response. Immunity is the only roguelite built on actual immunology — making it genuinely educational without ever feeling like homework. ▸ E. coli that groups and reforms ▸ Fibrin clots that regenerate HP ▸ Calcium oxalate crystals with mineral armor ▸ Platelet swarms that recruit more platelets ▸ A Cancer boss that proliferates when damaged Can the immune system hold?

BUILD THE STRONGEST STRAIN YOU CAN Pathogeneer is a strategy simulation game about engineering a one-of-a-kind strain, releasing it into the wild, and seeing how far it can spread. Start small. Mutate with purpose. Then watch the cascade come alive across the world map. Every run is different. Climate, host density, geography, travel routes, resistance, and your own decisions can turn a tiny outbreak into a global phenomenon—or stop it cold. MUTATE YOUR WAY Choose connected mutation paths that shape infection, spread, survival, mutation, and host jumping. Build for blistering heat, freezing climates, ocean crossings, quiet persistence, explosive movement, or something wonderfully strange. JUMP BETWEEN HOSTS Begin with plants, then unlock insects, birds, land animals, and humans. Each host has distinct targets, routes, strengths, and mutation paths. Carry successful genes into descendants and grow a powerful lineage over repeated runs. WATCH THE WORLD REACT Follow visible infection fronts, host-specific spread patterns, route attempts, biome barriers, deaths, recoveries, and major host shifts live on the map. Make a few meaningful choices during the run and change what happens next. CREATE STRAINS WORTH SHARING Archive your best creations, evolve inherited genes, chase higher cascade grades, complete daily missions, and collect ridiculous names such as Cranky Sneeze Parade or One-Eyed Romaine. How far can your strain spread before the world fights back?