HeartFlow vs Redo TAV

The HeartFlow® mobile app is a convenient way for clinician customers to see the status of their patients’ HeartFlow FFRct Analyses. Quickly scan a list of patients in your institution with the HeartFlow Analysis and view patients’ personalized 3D models with FFRct values. If you are not currently a HeartFlow customer but are curious to try the HeartFlow Analysis, you can still preview the 3D model in a quick introduction experience. Note: Important differences exist in how FFRct values are presented in the mobile app. Please contact HeartFlow Support (support@heartflow.com) with any questions. http://www.heartflow.com **** About HeartFlow: HeartFlow is transforming the way cardiovascular disease is diagnosed and treated. Our HeartFlow FFRct Analysis is a non-invasive cardiac test that creates a personalized 3D model of the heart. Clinicians use this analysis to evaluate blood flow to the heart and to help them determine the appropriate treatment pathway for each patient with suspected coronary artery disease (CAD). Why the HeartFlow Analysis matters: • Regulated medical device with FDA 510(k) clearance, CE mark and PMDA approval. • Substantial clinical evidence with more than 500 peer-reviewed articles • Centers for Medicare and Medicaid Services (CMS) approved reimbursement in the US • Recommended by NICE and mandated by NHS England and NHS Improvement through the MedTech Funding Mandate • Over 235 million patients in the US have access to the HeartFlow Analysis through their current health insurance • Improves clinical outcomes through earlier detection of CAD without intervention or adverse events - 83% reduction in unnecessary angiograms* • Helps reduce the overall cost of care - 26% reduction based on the mean one-year per-patient cost* • Leverages deep learning for product improvements in accuracy and turnaround time • Improves the overall patient experience and quality of life* - hear from a few of the more than 100,000 patients touched by HeartFlow on our web site The HeartFlow FFRct Analysis is commercially available in the United States, Canada, Europe, and Japan. The HeartFlow Mobile Application is only commercially available in the United States, Canada, and the UK. Don’t have HeartFlow at your institution? Submit a request, and we’ll help get the conversation started. http://www.heartflow.com/contact-us * Douglas, et al. J Am Coll Cardiol 2016; 68:435-45.

The Redo TAV app provides guidelines for assessing the suitability of a transcatheter aortic valve for Redo-TAV procedures using systematic CT analysis (Redo-TAV CT planning) and provides procedural guidance (Procedural Guide) for the procedure. The algorithm behind the app has been derived from extensive research of published materials on Redo-TAV procedures, including bench and CT simulation work. - Redo-TAV CT Planning After the user selects a particular valve type and size, Redo-TAV provides them with the valve's CT appearance and dimensions. Once the second valve is chosen, the app guides the user through different steps of assessment and collates the information. Using systematic step-by-step assessment, the app ensures that no aspect of assessment is missed. The app does not make recommendations to the user but simply guides them to the next step based on their choice. - Procedural Guide Based on the first valve type and size in the patient and the second valve chosen by the user, the app provides information on the height and depth of implant. When available, the app also includes a small clip of actual implant. - Procedure Data and Outcome The user is able to input important data points if desired to create a visual report.