Alveolar vs ECMO Bedside Guide

A-a oxygen gradient — The alveolar - arterial (A-a) oxygen gradient is a measure of oxygen transfer across alveolar capillary membrane (“A” denotes alveolar and “a” denotes arterial oxygenation). It is the difference between the amount of the oxygen in the alveoli. PAO2 = Alveolar oxygen tension PaO2 = Arterial oxygen tension A-a oxygen gradient = PAO2 - PaO2. PaO2 is derived from ABG while PAO2 is calculated. PAO2 = (FiO2 x [Patm - PH2O]) - (PaCO2 ÷ R) FiO2 is the fraction of inspired oxygen (0.21 at room air). Patm is the atmospheric pressure (760 mmHg at sea level). PH2O is the partial pressure of water (47 mmHg ). PaCO2 is derived from ABG , and R is the respiratory quotient. (The respiratory quotient is approximately 0.8 at normal physiological state) A-a gradient varies with age and can be estimated from the following equation, assuming the patient is breathing room air. A-a gradient = 2.5 + 0.21 x age in years A-a gradient increases with higher FiO2. PaO2/FiO2 ratio — The PaO2/FiO2 ratio is a measure of oxygen transfer across the alveolar capillary membrane . Normal PaO2/FiO2 ratio is 300 to 500 mmHg, with values less than 300 mmHg indicating impaired gas exchange and values less than 200 mmHg indicates severe hypoxemia . Concept By: Dr. Satish Deopujari Dr Vivek Shivhare Disclaimer: This app is based on equations available publicly in Medical domain.  The information contained on this app is intended for educational purposes only. It does not constitute medical advice. You should consult a physician regarding medical diagnosis or treatment.

Introducing the ECMO Bedside Guide from ELSO, the essential app for healthcare professionals managing patients on Extracorporeal Membrane Oxygenation (ECMO). Developed by the Extracorporeal Life Support Organization (ELSO), this comprehensive resource puts vital information at your fingertips—with or without an internet connection—streamlining ECMO care delivery. Key Features: - Rapid Calculations: Quickly determine BSA, flows, oxygenation parameters, and more with user-friendly calculators. - Comprehensive Checklists: Access step-by-step guides for ECMO management, troubleshooting, equipment, and other critical procedures. - Medication Guidance: Find detailed dosing information for commonly used medications in the ECMO setting. - Equipment Information: Review specifications and usage details for cannulas, pumps, and other essential equipment. - Candidacy Assessments: Evaluate adult and pediatric patients for ECMO using evidence-based criteria. - Emergency Support: The “Panic!” button provides immediate guidance for critical situations like air in the circuit or accidental decannulation, among others. - Offline Access: Utilize the app’s full functionality even without an internet connection! - Enhanced Privacy: No identifying patient information is collected or stored. The ECMO Bedside Guide is based on the latest evidence and recommendations from leading experts and the ELSO Red Book, 6th Edition. Download the app today and experience a new level of confidence in your ECMO practice.