180+ iOS apps & games curated and reviewed
If you already know Plague Inc., this is the deeper bench. 180+ disease game apps and games for iPhone, all reviewed and ranked by user rating, recency, and download trend as of May 2026.
Infect the world with your own deadly pathogen in a high-strategy simulation game. Evolve your plague to outsmart humanity's defenses in this thrilling and realistic game designed for iPhone users.
Spread your disease worldwide by evolving it with various symptoms and resistances in this exciting simulation game available on the App Store. Choose your level, select countries to infect, and use different transmission methods to strategize your outbreak. Download now for free!
Experience a terrifyingly realistic virus simulator where you play as "Patient Zero" and develop a deadly plague, adapting against humanity's efforts to stop you. Control the spread of disease across the globe, evolving a unique virus to determine the fate of humanity.
Experience a compelling biomedical strategy simulator where you control the fate of a patient by developing lethal illnesses in Bio Inc. Upgrade diseases, hinder recovery, and spread infections across various body systems. With 18 stages, 100 conditions, and engaging graphics, immerse yourself in this addictive game. Watch the trailer at [playbioinc.com](http://playbioinc.com) and challenge yourself with four difficulty settings. Can you reach the "Impossible Stage"?
Track and manage a virtual patient's medical journey, making critical decisions to save or sabotage their life in a medical simulation game. Will you cure or kill the patient? Play now and test your medical skills!
Experience the ultimate nuclear superpower simulation with intuitive gameplay and stunning graphics. Strategize as a global leader, making critical decisions to ensure your nation's survival. Embrace your destiny on Earth in this award-winning strategy game. Stay tuned for updates and download now!
Experience the ultimate zombie outbreak simulation app where you can create and customize your own zombie apocalypse in real-world locations using Google Maps. Watch the chaos unfold as you tweak outbreak parameters and save humanity by deploying resources strategically. Download now and unleash the apocalypse!
A global infection threatens humanity, and as a player, you must find a cure, navigate realistic world maps, collect resources, and upgrade abilities to defeat Dr. Plague. Join the fight to save the world from destruction and strategic play in Virus Plague: Survival Wars.
Unleash your inner alchemist in this magical idle game where you transform mushrooms into powerful potions to save the world. Unlock unique mushrooms, utilize magical power-ups, and work towards becoming a trillionaire. Embark on your quest now!
Create a world pandemic and conquer humanity in this strategic 3D game where you spread a deadly virus. Increase case numbers, decrease survival rates, and aim to become the deadliest threat the world has ever seen. Play now and witness the chaos unfold!
Experience worldwide arcade zombie chaos in this critically acclaimed game where you can transform people into zombies. Join the excitement today and unleash your undead creativity!
Manage all hospital departments, treat patients, and make strategic decisions to grow your medical center in this captivating management game. Upgrade facilities, handle emergencies, and build a top-tier healthcare empire. If you enjoy management games, step into the role of a hospital manager and lead your team to success!
"Engage in strategic warfare in this cellular strategy game where you defend and expand your cells against enemies using Attack, Defense, and Heal tactics. Explore easy controls, unique gameplay features, supportive items, and mini-games across multiple languages."
In this hospital time management game, players take on the roles of doctors and administrators to build and manage their own hospital, helping patients and upgrading facilities. With exciting level objectives, diverse patient cases, and customization options for hospital design, players can create their dream medical center. Start building your world-class hospital today!
Immerse yourself in a base defense game in an immune-themed world where you defend your fortress against waves of viruses by strategically placing pills and unlocking powerful characters. With dynamic gameplay and vibrant graphics, join the defense effort and keep the viral invaders at bay!
Experience the intense medical drama and time management challenges of becoming a doctor in a romantic story-driven game. Help Allison Heart navigate hospital life, diagnose patients, and race against time to find a cure in Heart's Medicine - Doctor's Oath. Join the adventure and subscribe to GameHouse Original Stories for more exciting gameplay.
Experience the thrill of a hospital simulation game with a captivating love story in this time management RPG. Play as aspiring surgeon Allison Heart, make life-saving decisions, navigate romance, and enjoy mini-games and challenges. Start saving lives and hearts today!
In this mobile game, students take on the role of a disease detective, investigating and solving outbreaks around the globe through interactive dialogue, puzzles, and mini-games. By playing this game, students can develop an interest in science, medicine, and public health while experiencing a fun and immersive adventure.
Immerse yourself in an epic war for survival against deadly enemies, guiding your life form to victory through genetic engineering and evolution. Prove your skills in viral combat with other microbiological organisms in a world under the microscope. Experience endless replay value with upgradable stats, challenging levels, and multiplayer interactions.