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Best Infection Game

172+ iOS apps & games curated and reviewed

4.4 avg rating
18 free apps & games
Updated July 2026

Every iPhone needs a few good infection game. We benchmark 172+ of them on App Store rating, freshness, and pricing, then surface the standouts so you don't have to scroll the App Store yourself.

Compare top Infection Game (July 2026)

#AppPriceRatingAdsIn-App PurchasesUpdated
1Plague Inc.Plague Inc.$0.994.8★ (163K)NoYesJul 2026
2Infection Bio WarInfection Bio WarFree4.6★ (20K)NoYesJul 2026
3Safe Zone The Check Point GameSafe Zone The Check Point GameFree3.4★ (499)YesNoJul 2026
4Bio Inc. - Biomedical PlagueBio Inc. - Biomedical PlagueFree4.4★ (2.4K)NoYesJul 2026
5Patient Zero: Virus gamePatient Zero: Virus gameFree4.6★ (4.1K)YesYesJul 2026
6Left to Survive: Zombie GamesLeft to Survive: Zombie GamesFree4.6★ (57K)YesYesJul 2026
7Bloons TD BattlesBloons TD BattlesFree4.8★ (367K)YesYesJul 2026
8InfectonatorInfectonatorFree4.7★ (1.9K)NoYesJul 2026

Top Picks for Infection Game

Plague Inc.#1

Plague Inc. by Ndemic Creations

Can you Infect the World?
Editor's Choice
🎮 Games
4.8😊(163K ratings)
$0.99In-App Purchases
#1in Games
Plague Inc. screenshot 1
Plague Inc. screenshot 2
Plague Inc. screenshot 3
Plague Inc. screenshot 4
Plague Inc. screenshot 5
Plague Inc. screenshot 6

A strategic simulation game where you evolve a deadly pathogen to infect the world and end humanity. Adapt your plague against global defenses and master different disease types to achieve victory. It's a high-stakes battle of strategy against the entire planet.

What We Love

  • 🚀 Addictive gameplay
  • 🤔 Challenging and thought-provoking
  • 👍 Realistic disease simulation
  • 💡 Unique scenarios and special disease types

Room to Improve

  • 💰 Expensive in-app purchases
  • 🕰️ Slow progression without paying
  • 🐛 Inconsistent game mechanics
Infection Bio War#2

Infection Bio War by Wildlife Studios

Spread the Plague!
Strong Contender
🎮 Games
4.6😊(20K ratings)
FreeIn-App Purchases
Infection Bio War screenshot 1
Infection Bio War screenshot 2
Infection Bio War screenshot 3
Infection Bio War screenshot 4
Infection Bio War screenshot 5

A strategy game where you infect the global population with a custom disease. Evolve your pathogen with various transmission methods, symptoms, and resistances to achieve world domination.

What We Love

  • 👍 Decent for a free app
  • 👍 Fun and addictive
  • 👍 Pretty great with a winning strategy
  • 👍 Great game, one small issue

Room to Improve

  • 🐛 Certain African countries won't grow
  • 🐛 Worm gamemode has a bug
  • 🐛 Scrolling issues
Safe Zone The Check Point Game#3

Safe Zone The Check Point Game by Muhammad Awais

See Papers & Contraband Please
Worth Considering
🎮 Games
3.4(499 ratings)
FreeAds
Safe Zone The Check Point Game screenshot 1
Safe Zone The Check Point Game screenshot 2
Safe Zone The Check Point Game screenshot 3
Safe Zone The Check Point Game screenshot 4
Safe Zone The Check Point Game screenshot 5

As a security officer, you must screen survivors entering a fortified safe zone during a viral outbreak. Inspect documents, scan for infections, search for contraband, and identify impostors to protect humanity's last hope. Upgrade your tools and defenses to manage the influx and maintain order.

More Infection Game apps to explore

4
Bio Inc. - Biomedical Plague
Bio Inc. - Biomedical Plague
Bio Inc. - Biomedical Plague
Diseases and infection RTS
Free

Develop lethal illnesses to determine a victim's fate in this biomedical strategy simulator. Upgrade diseases, boost risk factors, and slow recovery before doctors find a cure. Offers hours of gameplay with realistic conditions and numerous stages.

Biomedical strategy simulatorDevelop lethal illnessesUpgrade diseases and risk factors
🎮 Games
(2.4K)
free with in-app purchases
5
Patient Zero: Virus game
Patient Zero: Virus game
Patient Zero: Virus game
Apocalypse simulator
Free

Simulate the creation and spread of a deadly plague in this realistic apocalypse simulator. Adapt your pathogen against global efforts to stop it and decide the fate of humanity. It's a strategic test of biology and survival.

Hyper-realistic virus simulationDevelop and adapt unique diseasesGlobal infection across all countries
🎮 Games
(4.1K)
free with in-app purchases
6
Left to Survive: Zombie Games
Left to Survive: Zombie Games
Left to Survive: Zombie Games
Apocalypse multiplayer shooter
Free

Engage in intense zombie combat, build and defend your base, and battle other players in this action-shooter game. Save survivors, loot resources, and face challenging zombie bosses.

Kill hordes of zombiesDestroy enemy bases from a helicopterIntense PvP matches
🎮 Games
(57K)
free with in-app purchases
7
Bloons TD Battles
Bloons TD Battles
Bloons TD Battles
Realtime PvP Tower Defense
Free

Engage in real-time head-to-head strategy battles against other players. Deploy monkey towers, upgrade defenses, and control bloons to outwit your opponents in this competitive tower defense game.

Head-to-head multiplayerOver 20 custom tracks22 monkey towers with 8 upgrades
🎮 Games
(367K)
free with in-app purchases
8
Infectonator
Infectonator
Infectonator
Worldwide arcade zombie panic
Free

Unleash a global zombie apocalypse by strategically infecting countries. Upgrade your undead army, unlock special abilities, and turn the world into your personal zombie playground. Enjoy vibrant pixel art and a humorous take on the zombie genre.

Worldwide zombie infectionZombie virus upgradesUnlock special undead
🎮 Games
(1.9K)
free with in-app purchases
9
Zombie Outbreak Simulator
Zombie Outbreak Simulator
Zombie Outbreak Simulator
by Binary Space Pty Ltd
Free

Simulate and customize zombie outbreaks in real-world locations using Google Maps. Control outbreak parameters, observe chaos unfold, and even join the fight with military interventions. Explore thousands of player-created maps or offline options.

Real-world map simulation with Google Maps integrationCustomizable outbreak parameters (zombie speed, civilian numbers, etc.)Observe infection spread from satellite to street view
🎮 Games
(1.6K)
free with in-app purchases
10
Infection of the dead
Infection of the dead
Infection of the dead
Action puzzle game
Free

Embody a zombie in this action-puzzle game. Grow your horde by turning humans into zombies, overwhelming crowds and overcoming stage-specific challenges. The goal is to infect a set number of people to clear each level.

Play as a zombieGrow your zombie hordeCrowd-based action
🎮 Games
(56K)
free with in-app purchases
11
Ancient Planet Tower Defense
Ancient Planet Tower Defense
Ancient Planet Tower Defense
They're coming right for you!
Free

Defend an ancient stronghold from alien invaders using powerful technologies. Build and upgrade towers in a classic tower defense experience with unique levels and diverse enemies. Enjoy an offline, ad-free strategy game with a compelling storyline.

Classic Tower Defense gameplayBuild towers anywhere on the field40 unique levels
🎮 Games
(1.1K)
free with in-app purchases
12
Infection Rising
Infection Rising
Infection Rising
Infect, Control, Conquer!
Free

Play as a symbiote, spreading infection and defeating enemies. Conquer bosses to advance through levels in this action-packed game.

Play as a symbioteSpread infectionDefeat enemies
🎮 Games
(0)
ad-supported
13
World Plague Pandemic: Evolved Zombie Invaders
World Plague Pandemic: Evolved Zombie Invaders
World Plague Pandemic: Evolved Zombie Invaders
by Oliver Saylor
Free

Become the mastermind behind a global plague, evolving your virus to infect the world. Explore new game modes like Fighting the Cure and Survival, and utilize powerful bio-weapons to enhance your devastating spread. Upgrade your virus and conquer 9 level packs in this thrilling simulation.

Upgrade virus performanceFighting the Cure modeSurvival mode
🎮 Games
(70)
free with in-app purchases
14
Bacterial Takeover - Idle game
Bacterial Takeover - Idle game
Bacterial Takeover - Idle game
Grow your super bacteria army!
Free

Become a tycoon of deadly bacteria and conquer the universe in this addictive idle clicker game. Grow your army, discover rare minerals, and use nano-tech to destroy planets. Perfect for quick play sessions or long journeys.

Idle bacteria productionOffline playPlanet destruction
🎮 Games
(873)
free with in-app purchases
15
Bloons TD Battles 2
Bloons TD Battles 2
Bloons TD Battles 2
Competitive Tower Defense
Free

Engage in thrilling head-to-head tower defense battles. Choose powerful heroes and a variety of monkey towers to outmaneuver opponents in real-time matches. Compete across dynamic maps and customize your loadout to achieve victory.

Head-to-head PvP tower defensePowerful Heroes with unique abilities22 Monkey Towers with upgrade paths
🎮 Games
(50K)
free with in-app purchases
16
My Town Hospital: Doctor Games
My Town Hospital: Doctor Games
My Town Hospital: Doctor Games
Medical Clinic - Play as Nurse
Free

This interactive game allows children to role-play as doctors, nurses, or patients in a virtual hospital. Explore various rooms, diagnose and treat patients, and create imaginative medical stories. It's designed to be fun and educational for young minds.

Role-play as doctor, nurse, or patientExplore 7+ hospital locationsDiagnose and treat patients
📚 Education
(26K)
free with in-app purchases
17
Mini DAYZ: Zombie Survival
Mini DAYZ: Zombie Survival
Mini DAYZ: Zombie Survival
Vast offline pixel game
Free

Survive a harsh, post-apocalyptic pixel world by exploring, scavenging, and crafting. Manage your health, hunger, and thirst while fending off infected and wild animals. Adapt to changing weather and utilize natural resources to stay alive in this challenging offline survival game.

Explore randomly generated pixel art worldScavenge for food, ammo, and suppliesCraft advanced items and build bases
🎮 Games
(5.8K)
free
18
Bio inc. Redemption
Bio inc. Redemption
Bio inc. Redemption
Medical & Doctor Simulation
Free

Engage in a complex biomedical simulation where you can either create deadly illnesses to infect victims or lead a medical team to find cures. Explore two distinct campaigns, develop strategies, and compete in world tournaments. The game offers realistic medical scenarios with a focus on strategic decision-making.

Biomedical simulationCreate illnesses or find curesRealistic diseases and conditions
🎮 Games
(2.1K)
free with in-app purchases
19
Zombie Night Terror
Zombie Night Terror
Zombie Night Terror
Undead Horde Outbreak Ahead!
$6.99

Command a growing horde of zombies to infect humans and spread an apocalypse. Utilize a unique mutation system and destructive environments to overcome human defenses in this strategy action game.

Command a zombie hordeContaminate humans to grow your hordeUnique mutation system
🎮 Games
(3.3K)
paid
20
Heal Infected Game
Heal Infected Game
Heal Infected Game
Phrases & Bosses Heal Infected
Free

Engage in a unique rhythm-based game where you diagnose and heal corrupted characters. Use strategy and timing to cure infections, restore music, and unlock new challenges. A blend of music, strategy, and problem-solving for a satisfying experience.

Unique healing gameplay with tools and techniquesRhythm-based mini-games for healingDynamic and unpredictable character behavior
🎮 Games
(186)
free

FAQ about Infection Game

What is the best infection game for iPhone?
Plague Inc. tops our infection game ranking as of July 2026, with a 4.8-star average from 163K App Store ratings, and it's priced at $0.99.
Yes — 18 of the top infection game we rank are free to download, including Infection Bio War and Safe Zone The Check Point Game.
Plague Inc. has no ads and offers in-app purchases, according to its App Store listing as of July 2026.
We track 172+ infection game on the iOS App Store as of July 2026, ranked by rating, recency, and analysis of real user reviews.
Plague Inc. is a unique strategy simulation game where your goal is to evolve a deadly pathogen and infect the world, bringing about the end of human history. You must adapt your plague against everything humanity does to defend itself, making it a high-stakes battle of strategy.
The game features stunning retina graphics, a hyper-realistic world with advanced AI, and a comprehensive tutorial system. You can master 12 different disease types with unique strategies, infect over 50 countries, and evolve hundreds of traits. It also includes expansion updates like the Neurax Worm and Necroa Virus.