Best Infection Game

245+ iOS apps & games curated and reviewed

4.1 avg rating
18 free apps & games
Updated August 2026

Every iPhone needs a few good infection game. We benchmark 245+ of them on App Store rating, freshness, and pricing, then surface the standouts so you don't have to scroll the App Store yourself.

Compare top Infection Game (August 2026)

#AppPriceRatingAdsIn-App PurchasesUpdated
1Plague Inc.Plague Inc.$0.994.8★ (167K)NoYesSep 2026
2Infection Bio WarInfection Bio WarFree4.6★ (20K)NoYesSep 2026
3Safe Zone The Check Point GameSafe Zone The Check Point GameFree3.4★ (529)YesNoSep 2026
4Bio Inc. - Biomedical PlagueBio Inc. - Biomedical PlagueFree4.4★ (2.4K)NoYesSep 2026
5Patient Zero: Virus gamePatient Zero: Virus gameFree4.6★ (4.4K)YesYesSep 2026
6InfectonatorInfectonatorFree4.7★ (1.9K)NoYesSep 2026
7WW2 Countries At WarWW2 Countries At WarFree4.6★ (2.4K)YesYesSep 2026
8Infection - Board GameInfection - Board GameFree3.0★ (1)NoYesMay 2026

Top Picks for Infection Game

Plague Inc.#1

Plague Inc. by Ndemic Creations

Can you Infect the World?
Editor's Choice
🎮 Games
4.8😊(167K ratings)
$0.99In-App Purchases
#1in Games
Plague Inc. screenshot 1
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A strategic simulation game where you evolve a deadly pathogen to infect the world and end humanity. Adapt your plague against global defenses and master different disease types to achieve victory. It's a high-stakes battle of strategy against the entire planet.

What We Love

  • 🚀 Addictive gameplay
  • 🤔 Challenging and thought-provoking
  • 👍 Realistic disease simulation
  • 💡 Unique scenarios and special disease types

Room to Improve

  • 💰 Expensive in-app purchases
  • 🕰️ Slow progression without paying
  • 🐛 Inconsistent game mechanics
Infection Bio War#2

Infection Bio War by Wildlife Studios

Spread the Plague!
Strong Contender
🎮 Games
4.6😊(20K ratings)
FreeIn-App Purchases
Infection Bio War screenshot 1
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A strategy game where you infect the global population with a custom disease. Evolve your pathogen with various transmission methods, symptoms, and resistances to achieve world domination.

What We Love

  • 👍 Decent for a free app
  • 👍 Fun and addictive
  • 👍 Pretty great with a winning strategy
  • 👍 Great game, one small issue

Room to Improve

  • 🐛 Certain African countries won't grow
  • 🐛 Worm gamemode has a bug
  • 🐛 Scrolling issues
Safe Zone The Check Point Game#3

Safe Zone The Check Point Game by Muhammad Awais

See Papers & Contraband Please
Worth Considering
🎮 Games
3.4(529 ratings)
FreeAds
Safe Zone The Check Point Game screenshot 1
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As a security officer, you must screen survivors entering a fortified safe zone during a viral outbreak. Inspect documents, scan for infections, search for contraband, and identify impostors to protect humanity's last hope. Upgrade your tools and defenses to manage the influx and maintain order.

More Infection Game apps to explore

FAQ about Infection Game

What is the best infection game for iPhone?
Plague Inc. tops our infection game ranking as of August 2026, with a 4.8-star average from 167K App Store ratings, and it's priced at $0.99.
Yes — 18 of the top infection game we rank are free to download, including Infection Bio War and Safe Zone The Check Point Game.
Plague Inc. has no ads and offers in-app purchases, according to its App Store listing as of August 2026.
We track 245+ infection game on the iOS App Store as of August 2026, ranked by rating, recency, and analysis of real user reviews.
Plague Inc. is a unique strategy simulation game where your goal is to evolve a deadly pathogen and infect the world, bringing about the end of human history. You must adapt your plague against everything humanity does to defend itself, making it a high-stakes battle of strategy.
The game features stunning retina graphics, a hyper-realistic world with advanced AI, and a comprehensive tutorial system. You can master 12 different disease types with unique strategies, infect over 50 countries, and evolve hundreds of traits. It also includes expansion updates like the Neurax Worm and Necroa Virus.