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Best Plague Apps & Games

250+ iOS apps & games curated and reviewed

4.5 avg rating
18 free apps & games
Updated August 2026

If you already know Plague Inc., this is the deeper bench. 250+ plague apps and games for iPhone, all reviewed and ranked by user rating, recency, and download trend as of August 2026.

Compare top Plague Apps & Games (August 2026)

#AppPriceRatingAdsIn-App PurchasesUpdated
1Plague Inc.Plague Inc.$0.994.8★ (166K)NoYesAug 2026
2Infection Bio WarInfection Bio WarFree4.6★ (20K)NoYesAug 2026
3Last Asylum: PlagueLast Asylum: PlagueFree4.8★ (35K)NoYesAug 2026
4BitLife - Life SimulatorBitLife - Life SimulatorFree4.8★ (1.8M)YesYesAug 2026
5Bio Inc. - Biomedical PlagueBio Inc. - Biomedical PlagueFree4.4★ (2.4K)NoYesAug 2026
6Patient Zero: Virus gamePatient Zero: Virus gameFree4.6★ (4.4K)YesYesAug 2026
7Zombie Outbreak SimulatorZombie Outbreak SimulatorFree4.1★ (1.7K)YesYesAug 2026
8Zombie Infection Scan ZoneZombie Infection Scan ZoneFree2.6★ (145)YesNoAug 2026

Top Picks for Plague

Plague Inc.#1

Plague Inc. by Ndemic Creations

Can you Infect the World?
Editor's Choice
🎮 Games
4.8😊(166K ratings)
$0.99In-App Purchases
#1in Games
Plague Inc. screenshot 1
Plague Inc. screenshot 2
Plague Inc. screenshot 3
Plague Inc. screenshot 4
Plague Inc. screenshot 5
Plague Inc. screenshot 6

A strategic simulation game where you evolve a deadly pathogen to infect the world and end humanity. Adapt your plague against global defenses and master different disease types to achieve victory. It's a high-stakes battle of strategy against the entire planet.

What We Love

  • 🚀 Addictive gameplay
  • 🤔 Challenging and thought-provoking
  • 👍 Realistic disease simulation
  • 💡 Unique scenarios and special disease types

Room to Improve

  • 💰 Expensive in-app purchases
  • 🕰️ Slow progression without paying
  • 🐛 Inconsistent game mechanics
Infection Bio War#2

Infection Bio War by Wildlife Studios

Spread the Plague!
Strong Contender
🎮 Games
4.6😊(20K ratings)
FreeIn-App Purchases
Infection Bio War screenshot 1
Infection Bio War screenshot 2
Infection Bio War screenshot 3
Infection Bio War screenshot 4
Infection Bio War screenshot 5

A strategy game where you infect the global population with a custom disease. Evolve your pathogen with various transmission methods, symptoms, and resistances to achieve world domination.

What We Love

  • 👍 Decent for a free app
  • 👍 Fun and addictive
  • 👍 Pretty great with a winning strategy
  • 👍 Great game, one small issue

Room to Improve

  • 🐛 Certain African countries won't grow
  • 🐛 Worm gamemode has a bug
  • 🐛 Scrolling issues

More Plague apps to explore

4
BitLife - Life Simulator
BitLife - Life Simulator
BitLife - Life Simulator
Live your best (or worst) life
Free

Experience a text-based life simulator where every choice shapes your destiny. Build a dream life with love and career, or embrace chaos with crime and scandal. Your virtual life story unfolds with every decision.

Text-based life simulationChoice-driven roleplayingBuild a dream life
🎮 Games
(1.8M)
free with in-app purchases
5
Bio Inc. - Biomedical Plague
Bio Inc. - Biomedical Plague
Bio Inc. - Biomedical Plague
Diseases and infection RTS
Free

Develop lethal illnesses to determine a victim's fate in this biomedical strategy simulator. Upgrade diseases, boost risk factors, and slow recovery before doctors find a cure. Offers hours of gameplay with realistic conditions and numerous stages.

Biomedical strategy simulatorDevelop lethal illnessesUpgrade diseases and risk factors
🎮 Games
(2.4K)
free with in-app purchases
6
Patient Zero: Virus game
Patient Zero: Virus game
Patient Zero: Virus game
Apocalypse simulator
Free

Simulate the creation and spread of a deadly plague in this realistic apocalypse simulator. Adapt your pathogen against global efforts to stop it and decide the fate of humanity. It's a strategic test of biology and survival.

Hyper-realistic virus simulationDevelop and adapt unique diseasesGlobal infection across all countries
🎮 Games
(4.4K)
free with in-app purchases
7
Zombie Outbreak Simulator
Zombie Outbreak Simulator
Zombie Outbreak Simulator
by Binary Space Pty Ltd
Free

Simulate and customize zombie outbreaks in real-world locations using Google Maps. Control outbreak parameters, observe chaos unfold, and even join the fight with military interventions. Explore thousands of player-created maps or offline options.

Real-world map simulation with Google Maps integrationCustomizable outbreak parameters (zombie speed, civilian numbers, etc.)Observe infection spread from satellite to street view
🎮 Games
(1.7K)
free with in-app purchases
8
Zombie Infection Scan Zone
Zombie Infection Scan Zone
Zombie Infection Scan Zone
Border Quarantine Patrol Zone
Free

Explore a sealed quarantine zone filled with dangers like mutated threats and unstable environments. Your mission is to scan, report, and survive to uncover the truth behind a spreading outbreak. Manage limited gear and resources in hazardous sectors.

Explore abandoned streets and contaminated buildingsInvestigate mutated threats and unstable environmentsManage limited gear and resources
🎮 Games
(145)
ad-supported
9
After Inc.
After Inc.
After Inc.
What happens after Plague Inc?
$1.99

Rebuild civilization after a zombie apocalypse by building a settlement, exploring, and scavenging for resources. Make difficult societal decisions and defend against zombie threats in a persistent campaign.

Build and expand settlementsExplore a post-apocalyptic worldScavenge for resources
🎮 Games
(16K)
free with in-app purchases
10
WorldBox - God Sandbox
WorldBox - God Sandbox
WorldBox - God Sandbox
Best world building simulator!
Free

Create and shape your own pixel worlds with this god simulation sandbox game. Spawn creatures, build civilizations, and unleash powerful disasters or creative tools to watch life evolve. Experiment with various powers and enjoy offline play.

Create and spawn creaturesBuild and evolve civilizationsSimulate natural disasters
🎮 Games
(77K)
free with in-app purchases
11
Virus Plague: Survival Wars
Virus Plague: Survival Wars
Virus Plague: Survival Wars
World infection - Ways to Cure
Free

Lead the global effort to find a cure for a deadly infection unleashed by Dr. Plague. Strategically manage resources, upgrade abilities, and make critical decisions on a realistic world map to contain the outbreak and save humanity.

Fight the infectionRealistic world map trackingStrategic gameplay and decision-making
🎬 Entertainment
(30)
free with in-app purchases
12
Zombie Gunship Survival: AC130
Zombie Gunship Survival: AC130
Zombie Gunship Survival: AC130
Apocalypse Air Strike Shooter
Free

Defend humanity from a zombie apocalypse by providing air support from an AC-130 gunship. Lead survivor missions, gather resources, and build your base to repel relentless zombie assaults. Experience intense combat with realistic weaponry and high-definition visuals.

AC-130 gunship combatLead survivor scavenging missionsResource gathering and base building
🎮 Games
(58K)
free with in-app purchases
13
Zombie Plague
Zombie Plague
Zombie Plague
Brain Hunt Adventure
Free

Embark on a thrilling adventure in a zombie-infested world. Your mission is to outsmart hordes of the undead, catch brains, and survive eerie landscapes. Master strategic gameplay and upgrade your skills to face increasing challenges.

Explore haunting environmentsBrain-catching challengeStrategic gameplay
🎮 Games
(2)
ad-supported
14
Cosmic Plague
Cosmic Plague
Cosmic Plague
Cosmic Plague
Free

Navigate nanobots through the human circulatory system to combat a global cosmic microorganism outbreak. Compete with others to achieve the highest score and become the world champion in this action-packed game.

Navigate nanobotsCombat cosmic microorganismsCompete for high scores
🎮 Games
(1)
ad-supported
15
Cell to Singularity: Evolution
Cell to Singularity: Evolution
Cell to Singularity: Evolution
Civilization Idle Clicker Game
Free

Embark on an evolutionary journey from a single cell to a technological singularity. Tap to gain entropy, unlock new chapters of life, and witness milestones like dinosaur extinction and the Industrial Revolution. Explore the past, present, and future of humanity in this engaging idle clicker game.

Evolutionary clicker gameplayGain Entropy currencyUnlock chapters of life
🎮 Games
(23K)
free with in-app purchases
16
Dead Apocalypse Survival HD
Dead Apocalypse Survival HD
Dead Apocalypse Survival HD
by Thetis Consulting
Free

Fight hordes of zombies in a post-apocalyptic New York City. Utilize a vast arsenal of weapons and vehicles, including a tank, to complete missions and survive. Explore an open world, manage resources, and prove your zombie-killing skills.

55 missions and survival mode14 weapons and 12 vehicles11 unique hunters
🎮 Games
(3)
free with in-app purchases
17
Bio inc. Redemption
Bio inc. Redemption
Bio inc. Redemption
Medical & Doctor Simulation
Free

Engage in a complex biomedical simulation where you can either create deadly illnesses to infect victims or lead a medical team to find cures. Explore two distinct campaigns, develop strategies, and compete in world tournaments. The game offers realistic medical scenarios with a focus on strategic decision-making.

Biomedical simulationCreate illnesses or find curesRealistic diseases and conditions
🎮 Games
(2.2K)
free with in-app purchases
18
Nano Wars!
Nano Wars!
Nano Wars!
by Ristretto Studios
Free

Defend your system from invading microbes in this fast-paced tower defense game. Deploy units, use powerful medicine, and expand your defenses to push back infections. Collect molecules and upgrade your units to win the war.

Rapid-fire tower defense gameplayUnique immune system and medical abilitiesZone expansion for enemy path control
🎮 Games
(3)
ad-supported
19
Polluted Area
Polluted Area
Polluted Area
by CT Creative Team S.A.
Free

Engage in a challenging battle against pollution in this fast-paced game. Strategically manage toxic waste and radioactive materials across stunning 3D levels. Can you overcome the growing pollution and save the planet?

Fast-paced gameplayAddictive challengesStunning 3D graphics
🎮 Games
(1)
free with in-app purchases
20
BreakFree - Virus Shooter
BreakFree - Virus Shooter
BreakFree - Virus Shooter
An endless virus shooting game
Free

Engage in an endless arcade battle against a global virus threat. Use advanced weaponry and survive through progressively challenging years, aiming to keep the virus count below 100. Compete globally to save humanity.

Endless arcade gameplayVirus elimination challengesProgressive difficulty
🎮 Games
(1)
ad-supported

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FAQ about Plague

What are the best plague apps & games for iPhone?
Plague Inc. tops our plague apps & games ranking as of August 2026, with a 4.8-star average from 166K App Store ratings, and it's priced at $0.99.
Yes — 18 of the top plague apps & games we rank are free to download, including Infection Bio War and Last Asylum: Plague.
Plague Inc. has no ads and offers in-app purchases, according to its App Store listing as of August 2026.
We track 250+ plague apps & games on the iOS App Store as of August 2026, ranked by rating, recency, and analysis of real user reviews.
Plague Inc. is a unique strategy simulation game where your goal is to evolve a deadly pathogen and infect the world, bringing about the end of human history. You must adapt your plague against everything humanity does to defend itself, making it a high-stakes battle of strategy.
The game features stunning retina graphics, a hyper-realistic world with advanced AI, and a comprehensive tutorial system. You can master 12 different disease types with unique strategies, infect over 50 countries, and evolve hundreds of traits. It also includes expansion updates like the Neurax Worm and Necroa Virus.

Related searches

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