
littlEye AI
Histology AI for pathologists
About
What's New in littlEye AI
4.0
October 12, 2026
littlEye AI 4.0 — a new look and simpler work on Mac, iPad and iPhone. Shared .le3AI and .le3set files remain fully compatible with version 3.x in both directions. CLEARER NAVIGATION • The sidebar has 15 items in the order you work: Overview · Evaluate image · Work (Dataset, Cases, Review, Training, Models) · Research (Quantification, Desmin IHC, Measurement log) · Knowledge (Atlas, Education, Methodology, References) · About. • New Dataset section: all 27 organs as a grid grouped by organ system, with image and labelled counts. • On iPhone, five tabs: Overview · Evaluate · Dataset · Atlas · More. • Overview suggests the next step: import → assign diagnoses → review → train → evaluate and share. Collaboration and support reminders no longer sit above the working sections. • An image in progress, a result or a training run is not lost when you switch sections; training continues and the sidebar shows its progress. RESEARCH TOOLS AS AN INSTRUMENT • Quantification and Desmin IHC: the image and a large result with its interval side by side, settings and verification (fields, point counting, sensitivity) below; study mode as a status strip. • Desmin updates live, without an Evaluate button. Index 2 has a single path — the DAB + H&E image pair; Quantification sends the image to Desmin, not the numbers. • The measurement engine is 5 to 10 times faster and the threshold slider responds instantly. • The Measurement log is its own section: on the Mac a sortable table, deletion of single entries and CSV export via Save As. DATA AND SHARING • Complete backup including the measurement log and staining batches, and a new restore from backup — in Settings. • Reviews in .le3set files are matched through the diagnosis catalogue, images are not re-encoded on import (no quality loss) and exporting a model keeps its original author. • Slide review: digits 1–9, Space skips, ⌘Z undoes the last vote; vote ties are resolved deterministically. • The test set is split by case so that the test result is not inflated. • A damaged archive index is no longer overwritten — the app offers to restore the previous version. MAC • Settings (⌘,) with four tabs: General, Appearance, Reminders, Backup; a native About window. • New shortcuts: ⇧⌘A Dataset, ⇧⌘H Review, ⇧⌘L Measurement log, ⇧⌘I import images, ⇧⌘N new case, ⇧⌘E export model, ⌥⌘A Atlas in a new window; ⌘1–⌘0 stay. • Context menus and an inspector in Models. DESIGN AND ACCESSIBILITY • A unified design derived from the app icon, a full dark mode and colours with verified contrast. • VoiceOver labels for controls and charts, Dynamic Type, numbers formatted for the app language. 447 automated tests.
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