Inflammania vs Immunity

Inflammania - The Inflammation Game is a strategy game for everyone. Enter the fascinating world of the immune system! Become familiar with the good and bad sides of inflammation. Embark on exciting adventures in our body and protect it from diseases such as gout, Crohn's disease, asthma and rheumatism. In currently 5 worlds (Gut, Joint Gout, Joint Rheumatism, Joint Rheumatism II, Lung) you learn about complex, molecular mechanisms and drugs with their effects and adverse reactions. • Gout-Joint: Strategically position neutrophil granulocytes and catch uric acid crystals with their nets during a gout attack. • Rheumatism-Joint: Take different drugs in a targeted dose and stop the immune cells to attack your own body. • Lungs: Place leukotrin inhibitors and glucocorticoid drugs to eliminate the inflammatory tissue hormones and T lymphocytes to prevent an asthma attack. • Bowel: Fight against the influx of neutrophilic granulocytes with various drugs and become master of the inflammatory reaction in Crohn's disease. The game is developed within the Collaborative Research Centre 1181 "Checkpoints for Resolution of Inflammation" at the University Hospital Erlangen of the Friedrich-Alexander University Erlangen-Nuremberg. The development of the game is funded by the German Research Foundation.

YOU ARE THE LAST LINE OF DEFENSE. Play as a macrophage — the immune system's most powerful cell — and fight through 10 zones of the human body in this biology-based action roguelite. THE BODY IS UNDER ATTACK. From the Lymph Node to the Heart, real pathogens have invaded every organ. Bacteria. Parasites. Viruses. Kidney stones. Blood clots. Each zone brings new enemies grounded in actual cell biology — every creature, ability, and mechanic is based on how the immune system really works. BUILD YOUR IMMUNE RESPONSE. Every run is different. Collect 27+ adaptations and abilities as you progress — Cytokine Burst, Fever Mode, Phagocytosis, Neutrophil Swarm, Complement Cascade, and more. Stack upgrades. Build synergies. Adapt to every threat. 10 ZONES. 10 BOSSES. ▸ Lymph Node — face the Dormant Sentinel ▸ Lungs — battle the Pneumonia Mass ▸ Bloodstream — confront the Sepsis Herald ▸ Stomach — destroy H. Pylori Overlord ▸ Brain — survive the Neuroinflammation Prime ▸ Liver — fight the Cirrhosis Node ▸ Small Intestine — stop the Tapeworm Queen ▸ Large Intestine — dismantle the Bacterial Megacolony ▸ Kidneys — shatter the Nephrolithic Golem ▸ Heart — expel the Myocardial Invader THEN FACE THE FINAL BOSS. Cancer. The body's own cells gone wrong. A corrupted mirror of yourself. Three phases. Endless copies. No easy victory. ROGUELITE THAT RESPECTS YOUR TIME. ▸ Quick runs — each zone takes minutes ▸ Permanent upgrades carry between runs ▸ No energy systems. No paywalls. Play anytime. ▸ Every run feels different — 27+ items, abilities, and upgrades ▸ One more run feeling that turns five minutes into an hour LEARN WHILE YOU PLAY. Every enemy is a real pathogen. Every ability is a real immune response. Immunity is the only roguelite built on actual immunology — making it genuinely educational without ever feeling like homework. ▸ E. coli that groups and reforms ▸ Fibrin clots that regenerate HP ▸ Calcium oxalate crystals with mineral armor ▸ Platelet swarms that recruit more platelets ▸ A Cancer boss that proliferates when damaged Can the immune system hold?